20080

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/-
Location 3504819..3505618 Replicon chromosome
Accession HG738867
Organism Escherichia coli str. K-12 substr. MC4100

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag BN896_2836 Protein ID CDJ73729.1
Coordinates 3504819..3505283 (-) Length 155 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag BN896_2835 Protein ID CDJ73730.1
Coordinates 3505283..3505618 (-) Length 112 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN896_2839 3501930..3502403 - 474 CDJ73726.1 PTS system N-acetylgalactosamine-specific transporter subunit IIB -
BN896_2838 3502426..3503706 - 1281 CDJ73727.1 tagatose 6-phosphate aldolase 1, kbaZ subunit -
BN896_2837 3503955..3504764 + 810 CDJ73728.1 DNA-binding transcriptional regulator AgaR -
BN896_2836 3504819..3505283 - 465 CDJ73729.1 hypothetical protein Toxin
BN896_2835 3505283..3505618 - 336 CDJ73730.1 putative regulator PrlF Antitoxin
BN896_2834 3505767..3507338 - 1572 CDJ73731.1 (D)-galactarate dehydrogenase -
BN896_2833 3507713..3509047 + 1335 CDJ73732.1 putative (D)-galactarate transporter -
BN896_2832 3509063..3509833 + 771 CDJ73733.1 alpha-dehydro-beta-deoxy-D-glucarate aldolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 3504819..3516493 11674


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(12-150)

Antitoxin

(14-110)


Sequences


Toxin        


Download         Length: 155 a.a.        Molecular weight: 17836.25 Da        Isoelectric Point: 9.6924

>T20080 CDJ73729.1 HG738867:c3505283-3504819 [Escherichia coli str. K-12 substr. MC4100]
MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKN
KDWSRVKFGAGRYRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTRETEETH

Download         Length: 465 bp

>T20080 HG738867:c3505283-3504819 [Escherichia coli str. K-12 substr. MC4100]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12358.94 Da        Isoelectric Point: 4.8616

>AT20080 CDJ73730.1 HG738867:c3505618-3505283 [Escherichia coli str. K-12 substr. MC4100]
MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHYEILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNN
PQKTRPFNIQQGKKLVAGMDVNIDDEIGDDE

Download         Length: 336 bp

>AT20080 HG738867:c3505618-3505283 [Escherichia coli str. K-12 substr. MC4100]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References