SecReT6, T6SS database

Vibrionales

Experimental investigation has been performed.

Bioinformatics investigation has been performed

T6SS ID	Type	Organism	Replicon (Accession)	Location	Function
T6SS00790	i1	Vibrio cholerae V52	chromosome (NZ_KQ410497)	202021..225793	anti-bacterial; anti-eukaryotic; effector translocation; virulence; adherence
T6SS00044	i5	Vibrio parahaemolyticus RIMD 2210633	chromosome II (NC_004605)	1074208..1108114	anti-eukaryotic; effector translocation; adherence
T6SS00043	i1	Vibrio parahaemolyticus RIMD 2210633	chromosome I (NC_004603)	1486402..1526996	anti-eukaryotic; anti-bacterial; effector translocation; adherence; virulence
T6SS01112	i1	Vibrio cholerae strain A1552	chromosome (NZ_CP024868)	116945..140733	-
T6SS01168	i1	Vibrio cholerae C6706	chromosome (NZ_CP046845)	296505..315674	anti-bacterial; anti-eukaryotic
T6SS00719	i1	Vibrio parahaemolyticus BB22OP	chromosome I (NC_019955)	1464178..1493343	anti-bacterial
T6SS00084	i1	Aliivibrio fischeri ES114	chromosome I (NC_006840)	1087244..1118010	anti-bacterial
T6SS00720	i5	Vibrio parahaemolyticus BB22OP	chromosome II (NC_019971)	1048650..1070709	anti-bacterial
T6SS00002	i1	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome II (Vas) (NC_002506)	110871..145577	-
T6SS00802	Unknown	Vibrio anguillarum NB10	chromosome (GQ118992)	1..11619	effector translocation
T6SS00794	i5	Vibrio alginolyticus EPJS	chromosome (FJ790777)	1..31102	anti-bacterial
T6SS00793	i1	Vibrio alginolyticus EPJS	chromosome (FJ790776)	1..32212	effector translocation
T6SS00939	i5	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	1440993..1467006	anti-bacterial
T6SS00945	i1	Vibrio proteolyticus NBRC 13287	chromosome II (NZ_BATJ01000006)	17401..46675	anti-bacterial; anti-eukaryotic
T6SS01028	i1	Vibrio fluvialis 85003	chromosome (KY319183)	2525..21696	anti-bacterial
T6SS01029	i5	Vibrio fluvialis 85003	chromosome (KY319184)	1341..24915	anti-bacterial
T6SS01061	i1	Vibrio cholerae 2740-80	chromosome (NZ_CP016325)	116326..135495	-
T6SS01088	i1	Vibrio anguillarum strain MHK3	chromosome (NZ_CP022469)	244348..263491	anti-bacterial
T6SS01224	i1	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	100481..131233	anti-bacterial
T6SS01235	i1	Vibrio vulnificus 106-2A	chromosome (NZ_LMTD01000002)	158416..182116	anti-bacterial
T6SS01236	i5	Vibrio vulnificus 106-2A	chromosome (NZ_LMTD01000002)	431921..457308	anti-bacterial
T6SS01247	i1	Vibrio parahaemolyticus strain T9109	chromosome (NZ_JTGR01000038)	206703..237535	anti-bacterial
T6SS01250	i5	Vibrio parahaemolyticus strain D4	chromosome (NZ_NNJE01000049)	1..20649	anti-bacterial
T6SS01251	i1	Vibrio parahaemolyticus strain D4	chromosome (NZ_NNJE01000075)	1500..20954	anti-bacterial
T6SS01252	i5	Vibrio parahaemolyticus strain A3	chromosome (NZ_NNQJ01000119)	69..19440	anti-bacterial
T6SS01253	i5	Vibrio parahaemolyticus strain 12-009A/1335	chromosome (NZ_MYFF01000494)	7384..30649	anti-bacterial
T6SS01254	i1	Vibrio parahaemolyticus strain 12-009A/1335	chromosome (NZ_MYFF01000478)	10921..33508	anti-bacterial
T6SS01262	i1	Vibrio parahaemolyticus strain 12-297/B	chromosome (NZ_MYFG01000475)	22753..40086	anti-bacterial
T6SS01277	i1	Aliivibrio fischeri strain FQ-A001	chromosome (NZ_SJSX01000002)	747470..766109	anti-bacterial
T6SS01278	i1	Aliivibrio fischeri strain FQ-A001	chromosome (NZ_SJSX01000004)	316834..358016	anti-bacterial
T6SS01280	i5	Vibrio coralliilyticus OCN008	chromosome I (NZ_CP048693)	2761384..2787511	anti-bacterial
T6SS01281	i1	Vibrio coralliilyticus OCN008	chromosome II (NZ_CP048694)	1627613..1656598	anti-bacterial
T6SS01289	i1	Vibrio cholerae DL4211	chromosome (NZ_MOLL01000005)	54064..77732	anti-bacterial; anti-eukaryotic
T6SS01290	i1	Vibrio cholerae DL4215	chromosome (NZ_MOLM01000011)	74535..98377	anti-bacterial; anti-eukaryotic
T6SS01231	Unknown	Vibrio anguillarum L62	chromosome (-)	-	-
T6SS01232	Unknown	Vibrio anguillarum SMP1	chromosome (-)	-	-
T6SS01233	Unknown	Vibrio anguillarum L73	chromosome (-)	-	-
T6SS01234	Unknown	Vibrio anguillarum MHK9	chromosome (-)	-	-
T6SS01237	Unknown	Vibrio fluvialis VF42	chromosome (-)	-	-
T6SS01238	Unknown	Vibrio fluvialis CICC21612	chromosome (-)	-	-
T6SS01239	Unknown	Vibrio fluvialis VF54	chromosome (-)	-	-
T6SS01255	Unknown	Vibrio parahaemolyticus strain 12297B	chromosome (-)	-	anti-bacterial
T6SS01284	Unknown	Vibrio fischeri FQ-A002	chromosome (-)	-	anti-bacterial
T6SS01285	Unknown	Vibrio fischeri EBS004	chromosome (-)	-	anti-bacterial
T6SS01286	Unknown	Vibrio fischeri EBS004	chromosome (-)	-	anti-bacterial
T6SS17506	i1	Aliivibrio fischeri strain ES401	chromosome (NZ_SRJG01000005)	345059..392876	anti-bacterial

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Regulator ID	Locus tag (Gene)	Related T6SS	Regulator type	Regulatory pathway	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID	Target (Regulation)
REG0001	vfu_A02134 (ihfA)	T6SS00529 ; T6SS00530	protein	Transcription regulator	Vibrio furnissii NCTC 11218	chromosome (NC_016602)	2226951..2227244 (-)	490864172	tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0002	vfu_A02422 (ihfB)	T6SS00529 ; T6SS00530	protein	Transcription regulator	Vibrio furnissii NCTC 11218	chromosome (NC_016602)	2516092..2516376 (-)	490864456	tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓)
REG0020	Qrr4	T6SS01061	ncRNA	Unknown	Vibrio cholerae 2740-80	chromosome (NZ_CP016325)	-	-	VCA0107 mRNA (↑)
REG0021	GPY04_RS11195 (CytR)	T6SS01168	protein	Unknown	Vibrio cholerae C6706	chromosome (NZ_CP046844)	2449479..2450486 (-)	446146597	Unknown (↓)
REG0022	GPY04_RS03590 (TfoX)	T6SS01168	protein	QS regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	777344..777952 (+)	487807468	Unknown (↓)
REG0023	GPY04_RS00870 (HapR)	T6SS01168	protein	QS regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	164935..165546 (-)	446262243	Unknown (↓)
REG0024	GPY04_RS13335/VC0070 (tsrA)	T6SS01168	protein	Global regulator	Vibrio cholerae C6706	chromosome (NZ_CP046844)	2888303..2888587 (+)	445982516	T6SS transcripts (↑)
REG0025	Qrr1 quorum regulatory RNA	T6SS01168	ncRNA	QS regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	-	-	VCA0107 mRNA (↑)
REG0026	Qrr2 quorum regulatory RNA	T6SS01168	ncRNA	QS regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	-	-	VCA0107 mRNA (↑)
REG0027	Qrr3 quorum regulatory RNA	T6SS01168	ncRNA	QS regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	-	-	VCA0107 mRNA (↑)
REG0028	Qrr4 quorum regulatory RNA	T6SS01168	ncRNA	QS regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	-	-	VCA0107 mRNA (↑)
REG0029	GPY04_RS15835 (luxO)	T6SS01168	protein	QS regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046845)	273631..274983 (-)	446367907	VC0070 (tsrA) (↑); GPY04_RS00870 (hapR) (↑)
REG0030	GPY04_RS13825 (QstR)	T6SS01168	protein	Global regulator	Vibrio cholerae C6706	chromosome (NZ_CP046844)	2994333..2994977 (-)	447111060	Unknown (↓)
REG0033	GPY04_RS01040 (ChiS)	T6SS01168	protein	ChiS-induced regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	210606..213995 (-)	446410424	Necessory for TfoX/TfoR (↓)
REG0034	GPY04_RS03200 (chiA2)	T6SS01168	protein	ChiS-induced regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	692014..695280 (+)	487807405	GPY04_RS01040 (ChiS) (↓)
REG0035	GPY04_RS07700 (chiA1)	T6SS01168	protein	ChiS-induced regulatory pathway	Vibrio cholerae C6706	chromosome (NZ_CP046844)	1709613..1712153 (-)	446755770	GPY04_RS01040 (ChiS) (↓)
REG0036	VC1920/VCA1552_01695 (LonA)	T6SS01112	protein	Unknown	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	1845472..1847832 (-)	446970355	Unknown (↑)
REG0039	VC_RS13930 (VasH)	T6SS00002	protein	Global regulator	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	128790..130382 (+)	446006938	VCA0017 (hcp-2) transcript (↓)
REG0265	luxS	T6SS00793	protein	QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790776)	-	-	hcp1 transcript (↓)
REG0100	VP_RS12495 (barA)	T6SS00043 ; T6SS00044	protein	TCS-HK	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2712492..2715290 (+)	491625032	Hcp expression and secretion (↓)
REG0101	VP_RS09470 (UvrY)	T6SS00043 ; T6SS00044	protein	TCS-RR	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2037468..2038112 (-)	491529158	CsrB (↓)
REG0102	VP_RS12395 (CsrA)	T6SS00043 ; T6SS00044	protein	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2688313..2688510 (-)	490550575	Hcp and vgrG expression and secretion (↓)
REG0103	CsrB1	T6SS00043 ; T6SS00044	ncRNA	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2438728..2439035 (+)	-	VP_RS12395 (CsrA) (↑)
REG0104	CsrB2	T6SS00043 ; T6SS00044	ncRNA	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	3215766..3216162 (-)	-	VP_RS12395 (CsrA) (↑)
REG0105	CsrB3	T6SS00043 ; T6SS00044	ncRNA	carbon storage regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	plasmid (NC_004605)	171473..171785 (+)	-	VP_RS12395 (CsrA) (↑)
REG0106	vp2049 (Thymidylate kinase, Tmk)	T6SS00043	protein	Unknown	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2150113..2150745 (-)	28898823	T6SS1 (VgrG1) expression and secretion (↓)
REG0107	VP1028 (TfoY)	T6SS00043	protein	c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1077946..1078536 (-)	28897802	T6SS1 (VgrG1) expression and secretion (↓)
REG0108	vp1391	T6SS00043	protein	Global regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1491226..1492857 (-)	28898165	T6SS1 (VgrG1) expression and secretion (↓)
REG0109	vp1407	T6SS00043	protein	Unknown	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1511565..1512017 (-)	28898181	T6SS1 (VgrG1) expression and secretion (↓)
REG0110	VP1133 (hns)	T6SS00043	protein	Global regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1189718..1190125 (-)	28897907	VP1028 (TfoY) (↑)
REG0111	VP2762 (AphA)	T6SS00043 ; T6SS00044	protein	QS regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2929909..2930448 (+)	28899536	T6SS1 transcript (↑); T6SS2 (VPA1027-1024, VPA1043-1028,VPA1044-1046) transcripts (↑)
REG0112	VP2516 (opaR)	T6SS00043 ; T6SS00044	protein	QS regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2653215..2653829 (+)	28899290	vp1407 (↑); VP1388 promotor (↑); VP1400 promotor (↑); VP1409 promotor (↑); T6SS2 (Hcp2) expression and secretion (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1027-1024 transcript (↓); VPA1043-1028 transcript (↓); VPA1044-1046 transcript (↓)
REG0114	VP0820 (ToxR)	T6SS00043	protein	Transcription regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	847892..848770 (-)	28897594	VP1400 promotor (↑); VP1409 promotor (↑)
REG0115	VP0350 (CalR/LeuO)	T6SS00044	protein	Transcription regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	344763..345722 (+)	28897124	VPA1027 (hcp2) promotor (↓); VPA1043 (Fha) promotor (↓); VP1133 (H-NS) (↓)
REG0116	VPA1088 (cdpA)	T6SS00043	protein	c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	1147728..1150091 (+)	28900943	VP1028 (TfoY) (↑)
REG0117	VPA0739 (vdcA)	T6SS00043	protein	c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	772439..773809 (+)	28900594	VP1028 (TfoY) (↓)
REG0118	VP2516 (OpaR)	T6SS00043	protein	Global regulator	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	2653215..2653829 (+)	28899290	T6SS1 (↓)
REG0119	VP1241 (TfoX)	T6SS00044 ; T6SS00043	protein	QS regulatory pathway; c-di-GMP regulatory pathway	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1309223..1309810 (+)	28898016	T6SS2 (↓); T6SS1 (↓)
REG0122	VF2177 (LitR)	T6SS00084	protein	QS regulatory pathway	Aliivibrio fischeri ES114	chromosome (NC_006840)	2446537..2447142 (+)	59712784	Unknown (↓)
REG0123	VF0896 (TfoX)	T6SS00084	protein	Global regulator	Aliivibrio fischeri ES114	chromosome (NC_006840)	986000..986629 (+)	59711503	T6SS transcripts (↓)
REG0124	VFFQA001_02105 (rpoN)	T6SS01277	protein	Global regulator	Aliivibrio fischeri strain FQ-A001	chromosome (NZ_SJSX01000002)	62995..64464 (-)	501526930	hcp1/hcp transcript (↓)
REG0125	VFFQA001_15620 (VasH)	T6SS01278	protein	Global regulator	Aliivibrio fischeri strain FQ-A001	chromosome (NZ_SJSX01000004)	359608..360108 (+)	1027725198	Unknown (↓)
REG0180	VC0395_RS17530 (TsrA)	T6SS00208 ; T6SS00487	protein	Global regulator	Vibrio cholerae O395	chromosome (NC_009457)	2598392..2598676 (-)	445982516	T6SS Transciption (↑)
REG0181	VC0395_0020/VCA0117 (bEBP/vasH)	T6SS00208	protein	Global regulator	Vibrio cholerae O395	chromosome (NC_009456)	22315..23907 (-)	446006938	T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓)
REG0182	VC0395_A2109 (rpoN)	T6SS00208	protein	Global regulator	Vibrio cholerae O395	chromosome (NC_009457)	2265078..2266541 (+)	446727517	T6SS gene cluster promoter (PVCA0107/VC0395_RS00160) (↓); hcp promoter (PVCA0017/VC0395_0116) (↓)
REG0257	VEPGS_0614 (PppA)	T6SS00794	protein	Tpp	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	15765..16880 (+)	225382180	LuxR (↓)
REG0258	VEPGS_0606 (PpkA2)	T6SS00794	protein	Tpp	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	3227..5377 (-)	225382172	LuxR (↓); VEPGS_0610 (DotU2) (↓)
REG0259	VEPGS_0607 (Fha2)	T6SS00794	protein	Tpp	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	5690..6775 (+)	225382173	VEPGS_0610 (DotU2) (↓)
REG0260	EPGS_00471 (VtsR)	T6SS00794	protein	QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	-	-	LuxO (↓)
REG0261	EPGS_00471 (VtsR)	T6SS00793	protein	QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790776)	-	-	LuxO (↑)
REG0262	luxR	T6SS00794	protein	QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	-	-	T6SS2 transcript and expression (↓)
REG0263	luxR	T6SS00793	protein	QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790776)	-	-	T6SS1 transcript and expression (↑)
REG0264	VEPGS_0621 (pppA)	T6SS00793	protein	Tpp; QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	23577..24245 (+)	225382187	Unknown (↑); T6SS1 transcript (↑); hcp1 transcript (↓)
REG0266	LuxO	T6SS00793	protein	QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790776)	-	-	hcp1 transcript (↓)
REG0267	LuxO	T6SS00794	protein	QS regulatory pathway	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	-	-	Unknown (↑)
REG0268	rpoN	T6SS00793	protein	Transcription regulator	Vibrio alginolyticus strain EPJS	chromosome (FJ790776)	-	-	T6SS1 transcript (↓)
REG0269	VasH	T6SS00793	protein	Transcription regulator	Vibrio alginolyticus strain EPJS	chromosome (FJ790776)	-	-	T6SS1 transcript (↓)
REG0275	V12G01_21538 (LuxR)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000053)	13551..14165 (-)	91187814	T6SS2 transcripts (↓); V12G01-18672 (vqsA) promotor
REG0276	V12G01_19736 (TfoX)	T6SS00939	protein	Transcription regulator	Vibrio alginolyticus 12G01	chromosome (AAPS01000019)	47689..48276 (-)	91189146	T6SS2 transcripts (↓)
REG0277	V12G01_20658 (TfoY)	T6SS00939	protein	Transcription regulator	Vibrio alginolyticus 12G01	chromosome (AAPS01000039)	21665..22255 (+)	91188194	T6SS transcripts (↓)
REG0278	V12G01_20201 (H-NS)	T6SS00939	protein	Transcription regulator	Vibrio alginolyticus 12G01	chromosome (AAPS01000015)	63783..64190 (+)	91189474	VaT6SS1 transcripts (↑)
REG0279	V12G01_18672 (vqsA)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000003)	114208..115086 (+)	91191289	V12G01-21538 (luxR) promoter (↓); V12G01-14830 (aphA) promoter (↓); V12G01-18672 (vqsA) promotor (↓)
REG0280	V12G01_10813 (AsnC)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000004)	181050..181484 (-)	91191052	V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0281	V12G01_02325 (HP)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000004)	115263..116411 (+)	91190993	V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0282	V12G01_01665 (HP)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000007)	185299..185712 (+)	91190406	V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0283	V12G01_06711 (HP)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000024)	47707..48585 (-)	91188835	V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0284	V12G01_16177 (MetR)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000023)	58420..59331 (-)	91188901	V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0285	V12G01_02620 (SoxR)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000004)	181050..181484 (-)	91191052	V12G01-21538 (luxR) promoter; V12G01-14830 (aphA) promoter
REG0287	V12G01_14830 (aphA)	T6SS00939	protein	QS regulatory pathway	Vibrio alginolyticus 12G01	chromosome (AAPS01000027)	42305..42880 (+)	91188695	V12G01-18672 (vqsA) promotor
REG0288	VCA0566 (VxrB)	T6SS00002	protein	TCS-RR	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	504728..505384 (+)	446737785	Unknown (↑)
REG0289	VCA0933 (CspV)	T6SS00002	protein	c-di-GMP regulatory pathway	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	886068..886280 (+)	446027150	Unknown (↓)
REG0290	VCA1552_01380 (VdcA/ycdT)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	1482426..1483715 (+)	446892247	the levels of c-di-GMP (↑)
REG0291	VCA1552_02536 (CdpA/YfgF)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	2739669..2742158 (-)	446417730	the levels of c-di-GMP (↓)
REG0292	VCA1552_02898 (VasH)	T6SS01112	protein	Global regulator	Vibrio cholerae strain A1552	chromosome (NZ_CP024868)	128889..130481 (+)	446006938	VCA1552_00900 (TfoX) (↓)
REG0293	VCA1552_00351 (HapR)	T6SS01112	protein	Global regulator	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	340447..341058 (-)	446262243	Unknown; Hcp expression and secretion
REG0294	VCA1552_RS04890 (ihfA)	T6SS01112	protein	Transcription regulator	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	1028170..1028466 (+)	447152004	Hcp secretion (↓)
REG0295	VCA1552_RS08565 (ihfB)	T6SS01112	protein	Transcription regulator	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	1839353..1839631 (-)	446089486	Hcp secretion (↓)
REG0296	VCA1552_RS03895 (LuxO)	T6SS01112	protein	QS regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	818142..819509 (+)	487814784	Hcp expression and secretion (↑)
REG0297	VCA1552_RS17020 (cqsa)	T6SS01112	protein	QS regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024868)	455238..456407 (-)	446962656	Hcp expression and secretion (↓)
REG0298	VCA1552_RS01665 (LuxS)	T6SS01112	protein	QS regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	319588..320106 (+)	447052971	Hcp expression and secretion (↓)
REG0299	VCA1552_RS00505 (hfq)	T6SS01112	protein	QS regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	92673..92936 (+)	446974616	VCA1552_00351 (HapR) (↑)
REG0300	VCA1552_RS11610 (RpoN)	T6SS01112	protein	Global regulator	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	2488023..2489486 (+)	446727517	Hcp expression and secretion (↓)
REG0301	VCA1552_RS12025 (crp)	T6SS01112	protein	QS regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	2558371..2559003 (+)	446164894	Hcp expression and secretion (↓)
REG0302	VCA1552_RS12925 (cya)	T6SS01112	protein	QS regulatory pathway; cAMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	2747346..2749877 (-)	447072406	VCA1552_RS12025 (crp) (↓)
REG0303	VCA1552_00154 (QstR)	T6SS01112	protein	c-di-GMP regulatory pathway; QS regulatory pathway; Global regulator	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	149920..150564 (-)	447111060	TssB/TfoY transcripts (↓); VC0396/VCA1552_00154 (QstR) (↓); T6SS transcripts (↓)
REG0304	VCA1552_00900 (TfoX)	T6SS01112	protein	Global regulator	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	952868..953476 (+)	487807468	VC0396/VCA1552_00154 (QstR) (↓)
REG0306	VCA1552_01510 (TfoY)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	1636980..1637567 (+)	446282733	Unknown (↓)
REG0307	VCA1552_RS06160 (lonA)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	1315238..1316887 (+)	446116573	VCA1552_01510 (TfoY) (↑)
REG0308	VCA1552_RS10420 (cdgL)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	2215844..2217361 (-)	446975354	the levels of c-di-GMP (↓)
REG0309	VCA1552_RS04310 (cdgK)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	901594..903063 (+)	487807420	the levels of c-di-GMP (↓)
REG0310	VCA1552_RS04130 (cdgH)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	861187..863208 (+)	446848493	the levels of c-di-GMP (↓)
REG0311	VCA1552_RS02130 (rocS)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	425233..427287 (-)	447034155	the levels of c-di-GMP (↑)
REG0312	VCA1552_RS12850 (cdgJ)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	2733319..2734545 (-)	446210986	the levels of c-di-GMP (↑)
REG0313	VCA1552_RS17835 (cdgD)	T6SS01112	protein	c-di-GMP regulatory pathway	Vibrio cholerae strain A1552	chromosome (NZ_CP024868)	633312..635195 (+)	446210820	the levels of c-di-GMP (↓)
REG0314	TfoY	T6SS00790	protein	Global regulator	Vibrio cholerae V52	chromosome (-)	-	-	Unknown (↓)
REG0315	VCV52_RS10780 (TfoX)	T6SS00790	protein	Global regulator	Vibrio cholerae V52	chromosome (NZ_KQ410501)	68827..69435 (-)	487807468	Unknown (↓)
REG0316	VCV52_RS01020 (VasH)	T6SS00790	protein	Global regulator	Vibrio cholerae V52	chromosome (NZ_KQ410497)	212259..213851 (-)	446006947	Unknown (↓)
REG0317	VCV52_RS13040 (rpoN)	T6SS00790	protein	Global regulator	Vibrio cholerae V52	chromosome (NZ_KQ410502)	216932..218395 (-)	446727517	Unknown (↓)
REG0320	VC_A0122	T6SS00002	protein	Transcription regulator	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	137379..137621 (+)	9657509	hcp-2 expression (↓)
REG0329	VPBB_RS05425 (H-NS)	T6SS00719	protein	Transcription regulator	Vibrio parahaemolyticus BB22OP	chromosome (NC_019955)	1170475..1170882 (-)	505109423	VgrG1 expression and secretion (↑)
REG0355	N779_15250 (VtpR)	T6SS01280 ; T6SS01281	protein	QS regulatory pathway	Vibrio coralliilyticus OCN008	chromosome (AVOO01000045)	7579..8184 (-)	536747482	Unknown (↓)
REG0369	VCV52_RS14135 (wigR/phoB/vxrB)	T6SS00790	protein	TCS-RR	Vibrio cholerae V52	chromosome (NZ_KQ410503)	201806..202495 (-)	446013262	T6SS transcription level (↓)
REG0371	VFES401_RS15770 (tasR)	T6SS17506	protein	Unknown	Aliivibrio fischeri strain ES401	chromosome (NZ_SRJG01000005)	373862..374311 (+)	WP_012535053.1	hcp promotor (↓)
REG0373	hapR	T6SS01028 ; T6SS01029	protein	QS regulatory pathway	Vibrio fluvialis 85003	chromosome (KY319184)	-	-	vgrG (↓)
REG0374	ihfA	T6SS01028 ; T6SS01029	protein	QS regulatory pathway	Vibrio fluvialis 85003	chromosome (KY319184)	-	-	vgrG (↓)
REG0375	ihfB	T6SS01028 ; T6SS01029	protein	QS regulatory pathway	Vibrio fluvialis 85003	chromosome (KY319184)	-	-	vgrG (↓)

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Effector ID	Locus tag (Gene)	Classification	Cognate immunity protein	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	NCBI ID
EFF01832	VPBB_RS15030 (Tme1)	Tme	IMU00352	T6SS00719	Vibrio parahaemolyticus BB22OP	chromosome (NC_019955)	3247654..3248586 (+)	505110423
EFF01834	PO79_RS05910 (Tme2)	Tme	IMU00353	T6SS01247	Vibrio parahaemolyticus strain T9109	chromosome (NZ_JTGR01000043)	165330..166532 (+)	835943566
EFF01524	VPR01S_11_01570	DddA	-	T6SS00945	Vibrio proteolyticus NBRC 13287	chromosome (BATJ01000011)	161248..163059 (+)	543441460
EFF01442	VCA0285	Tae	IMU00291	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	305200..305871 (+)	15601051
EFF01294	VP_RS06875	Tde	IMU00052	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1522167..1524323 (+)	28898189
EFF01295	VP_RS21220	Tde	-	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	1341875..1344451 (+)	28901118
EFF01454	V12G01_RS33945	Tde	IMU00336	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902590)	213122..213841 (+)	491519344
EFF01455	V12G01_RS35200	Tde	IMU00337	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902590)	504752..509137 (-)	491519899
EFF01800	VPR01S_RS21945	Tde	-	T6SS00945	Vibrio proteolyticus NBRC 13287	chromosome (NZ_BATJ01000004)	229175..229945 (-)	545468119
EFF01530	V12_14465 (PoNe)	Tde	IMU00334 ; IMU00351	T6SS01262	Vibrio parahaemolyticus strain 12-297/B C4271	chromosome (NZ_MYFG01000470)	18950..20299 (-)	659039135
EFF00005	VCA0123	Tge	IMU00172	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	137581..140634 (+)	15600894
EFF00008	VC1418 (TseL, Tle2)	Tle	IMU00156	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002505)	1514611..1516536 (+)	15641429
EFF01818	GPY04_RS04830 (TleV1)	Tle	IMU00356	T6SS01168	Vibrio cholerae C6706	chromosome (NZ_CP046844)	1067605..1069530 (+)	446298981
EFF00003	VCA0020 (VasX)	Tme	IMU00166	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	23395..26652 (+)	15600791
EFF01457	V12G01_RS33215	Tme	IMU00339	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902590)	51252..54761 (-)	491519127
EFF01456	V12G01_RS27070	Tme	IMU00338	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	494035..494997 (+)	491516494
EFF01461	V12G01_RS25410	Tpe	-	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	98312..100468 (-)	491515716
EFF01293	VP_RS06745	Tse	IMU00051	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1483454..1485205 (+)	28898162
EFF01460	V12G01_RS25535	Tse	-	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	138873..140624 (-)	491515792
EFF01533	V12_14465 (PoNe)	Tse	-	T6SS01262	Vibrio parahaemolyticus strain 12-297/B C4271	chromosome (NZ_MYFG01000470)	17970..18953 (-)	639578399
EFF01820	GPY04_RS16385 (VasX)	Tme	IMU00357	T6SS01168	Vibrio cholerae C6706	chromosome (NZ_CP046845)	405867..409124 (-)	445992499
EFF00001	VCA0017	-	-	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	19781..20299 (+)	15600788
EFF00002	VCA0018	-	-	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	20427..22511 (+)	15600789
EFF00004	VCA0118	-	-	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	130352..131035 (+)	15600889
EFF00007	VC_RS06850	-	-	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002505)	1510278..1513769 (+)	15641427
EFF00006	VC_RS06845	-	-	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002505)	1509632..1510150 (+)	15641426
EFF01829	B5C30_RS14470 (VgrG1b)	-	-	T6SS01262	Vibrio parahaemolyticus strain 12-297/B C4271	chromosome (NZ_MYFG01000470)	20614..22692 (-)	490886759
EFF00060	VP_RS06770	-	-	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1495971..1496489 (+)	28898167
EFF00061	VP_RS20100	-	-	T6SS00044	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	1081544..1082023 (-)	28900882
EFF01019	VEPGS_0021 (hcp1)	-	-	T6SS00793	Vibrio alginolyticus strain EPJS	chromosome (FJ790776)	27427..27945 (-)	225382164
EFF01534	V12G01_01540 (hcp1)	-	-	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	127580..128098 (-)	491515782
EFF01535	V12G01_07583 (hcp2)	-	-	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	1464340..1464819 (+)	491518336
EFF01536	V12G01_01440 (PAAR)	-	-	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	100481..101938 (-)	491515718
EFF01537	V12G01_07588 (VgrG2)	-	-	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	1464869..1466704 (+)	491518337
EFF01819	GPY04_RS04820 (VgrG-1)	-	-	T6SS01168	Vibrio cholerae C6706	chromosome (NZ_CP046844)	1063272..1066763 (+)	446134261
EFF01821	GPY04_RS15920	-	IMU00358	T6SS01168	Vibrio cholerae C6706	chromosome (NZ_CP046845)	291886..294939 (-)	446035440
EFF01824	VEPGS_0623 (hcp2)	-	-	T6SS00794	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	27328..27807 (+)	225382189
EFF01830	VPBB_RS06670 (VgrG1)	-	-	T6SS00719	Vibrio parahaemolyticus BB22OP	chromosome (NC_019955)	1467896..1469974 (+)	505109564
EFF01831	VPBB_RS19920 (Hcp2)	-	-	T6SS00720	Vibrio parahaemolyticus BB22OP	chromosome (NC_019971)	1050543..1051022 (-)	491518336
EFF01833	PO79_RS04645 (VgrG1)	-	-	T6SS01247	Vibrio parahaemolyticus strain T9109	chromosome (NZ_JTGR01000038)	231739..233817 (-)	491637679
EFF01850	VCA1552_RS05805 (hcp)	-	-	T6SS01112	Vibrio cholerae strain A1552	chromosome (NZ_CP024867)	1238150..1238668 (+)	447065691
EFF01010	VCV52_RS01015	-	-	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	211606..212262 (-)	WP_001223375.1
EFF01011	VCV52_RS00990 (vgrG3)	-	IMU00272	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	202021..205074 (-)	WP_000113305.1
EFF18629	tssD2_a	-	IMU17309	T6SS01028	Vibrio fluvialis strain 85003	chromosome (KY319185)	1820..2338 (+)	ARK19412.1
EFF18630	tssD2_b	-	IMU17310	T6SS01028	Vibrio fluvialis strain 85003	chromosome (KY319186)	2484..3002 (+)	ARK19415.1
EFF76626	VCV52_RS00220	Tae	IMU38206	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	32099..32770 (-)	WP_000132861.1
EFF76627	VCV52_RS01470 (vasX)	Tme	IMU38207	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	316035..319292 (-)	WP_000070352.1
EFF76628	VCV52_RS01485 (hcp2)	-	-	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	322388..322906 (-)	WP_001142930.1
EFF76629	VCV52_RS01480	-	-	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	320176..322260 (-)	WP_000212092.1
EFF76630	VCV52_RS06825 (tseL)	Tle	IMU38208	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410498)	432292..434217 (-)	WP_000376836.1
EFF76631	VCV52_RS06835 (vgrG1)	-	-	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410498)	435059..438550 (-)	WP_000212116.1
EFF76632	VCV52_RS06840 (hcp2)	-	-	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410498)	438678..439196 (-)	WP_001142947.1

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Immunity protein ID	Locus tag (Gene)	Related T6SS	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Cognate effector
IMU00051	VP_RS06750	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1485278..1486405 (+)	28898163	EFF01293
IMU00052	VP_RS06880	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004603)	1524323..1524916 (+)	28898190	EFF01294
IMU00156	VC1419 (TsiV1)	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002505)	1516533..1517276 (+)	15641430	EFF00008
IMU00166	VCA0021 (TsiV2)	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	26653..27381 (+)	15600792	EFF00003
IMU00172	VCA0124 (TsiV3)	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	140631..140999 (+)	15600895	EFF00005
IMU00275	Vti2	T6SS00043	Vibrio parahaemolyticus RIMD 2210633	chromosome (NC_004605)	-		-
IMU00291	VC_RS14695	T6SS00002	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002506)	305996..306223 (+)	15601052	EFF01442
IMU00353	PO79_RS05915 (Tmi2)	T6SS01247	Vibrio parahaemolyticus strain T9109	chromosome (NZ_JTGR01000043)	166529..166984 (+)	646368409	EFF01834
IMU00334	V12_14460 (PoNi)	T6SS01262	Vibrio parahaemolyticus strain 12-297/B C4271	chromosome (NZ_MYFG01000470)	17970..18953 (-)	639578399	EFF01530
IMU00336	V12G01_RS33950	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902590)	213838..214413 (+)	91190683	EFF01454
IMU00337	V12G01_RS35195	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902590)	503860..504759 (-)	91191211	EFF01455
IMU00338	V12G01_03170	T6SS00939	Vibrio alginolyticus 12G01	chromosome (CH902589)	493354..493740 (+)	91191162	EFF01456
IMU00339	V12G01_RS33210	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902590)	50304..51248 (-)	91188895	EFF01457
IMU00340	V12G01_RS33565	T6SS00939	Vibrio alginolyticus 12G01	chromosome (NZ_CH902590)	137211..138782 (+)	91190385	-
IMU00341	V12G01_01430	T6SS01224	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	97561..98319 (-)	91190359	-
IMU00348	EPGS_03541 (rhsI1)	T6SS00794	Vibrio alginolyticus strain EPJS	chromosome (FJ790777)	-	-	-
IMU00351	B5C30_RS14460	T6SS01262	Vibrio parahaemolyticus strain 12-297/B C4271	chromosome (NZ_MYFG01000470)	17970..18953 (-)	639578399	EFF01530
IMU00352	VPBB_RS15035 (Tmi1)	T6SS00719	Vibrio parahaemolyticus BB22OP	chromosome (NC_019955)	3248576..3249004 (+)	491520929	EFF01832
IMU00356	GPY04_RS04835 (TsiV1)	T6SS01168	Vibrio cholerae C6706	chromosome (NZ_CP046844)	1069527..1070270 (+)	446694188	EFF01818
IMU00357	GPY04_RS16380 (TsiV2)	T6SS01168	Vibrio cholerae C6706	chromosome (NZ_CP046845)	405138..405866 (-)	446826823	EFF01820
IMU00358	GPY04_RS15915 (TsiV3)	T6SS01168	Vibrio cholerae C6706	chromosome (NZ_CP046845)	291521..291889 (-)	446984039	EFF01821
IMU00359	V12G01_RS26200	T6SS01224	Vibrio alginolyticus 12G01	chromosome (NZ_CH902589)	308691..309341 (-)	91190980	EFF01441
IMU00272	VCV52_RS00985	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	201656..202024 (-)	WP_001061295.1	EFF01011
IMU17309	tssI2_a	T6SS01028	Vibrio fluvialis strain 85003	chromosome (KY319185)	2490..4556 (+)	ARK19413.1	EFF18629
IMU17310	tssI2_b	T6SS01028	Vibrio fluvialis strain 85003	chromosome (KY319186)	3154..5250 (+)	ARK19416.1	EFF18630
IMU38206	VCV52_RS20260	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	31747..31974 (-)	WP_001911595.1	EFF76626
IMU38207	VCV52_RS01465	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410497)	315306..316034 (-)	WP_000904079.1	EFF76627
IMU38208	VCV52_RS06820	T6SS00790	Vibrio cholerae V52	chromosome (NZ_KQ410498)	431552..432295 (-)	WP_000771534.1	EFF76630

Experimental investigation has been performed.

Bioinformatics investigation has been performed

ID	Locus tag (Gene)	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Response to T6SS attack	Known or putative function
RSF000033	VCV52_0688 (wigR/phoB/vxrB)	Vibrio cholerae V52	chromosome (NZ_KQ410503)	201806..202495 (-)	446013262	protective	cell-wall damage response
RSF000034	VCV52_RS11930 (vpsA)	Vibrio cholerae V52	chromosome (NZ_KQ410501)	316448..317566 (-)	446679410	protective	Vibrio polysaccharide (VPS) expression

Experimental investigation has been performed.

Bioinformatics investigation has been performed

Accessory protein ID	Locus tag (Gene)	Related T6SS	Type	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI	Related structure protein	Related effector
ACP00001	VC1417	T6SS00002	adaptor	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002505)	1513748..1514608 (+)	15641428	VgrG-1	VC1418 (TseL)
ACP00025	VCV52_1391 (tap-1)	T6SS00790	adaptor	Vibrio cholerae V52	chromosome (NZ_KQ410498)	434220..435080 (-)	446336115	VgrG-1	TseL
ACP00026	VCV52_RS01475 (vasW)	T6SS00790	adaptor	Vibrio cholerae V52	chromosome (NZ_KQ410497)	319289..320176 (-)	447180717	-	VasX
ACP00041	A55_1501 (tap-2)	-	adaptor	Vibrio cholerae 1587	chromosome (NZ_KQ410627)	235783..236571 (+)	446538621	VgrG-1	TseL
ACP44067	VCV52_RS01000 (tagA)	T6SS00790	structure affiliated protein	Vibrio cholerae V52	chromosome (NZ_KQ410497)	205313..206575 (-)	WP_000073086.1	VCV52_RS01060 (tssE); VCV52_RS01055 (tssF); VCV52_RS01030 (tssL); VCV52_RS01005 (tssM)	VCV52_RS06835 (vgrG1); VCV52_RS00990 (vgrG3); VCV52_RS01485 (hcp-2)