Detailed information of regulator


Summary

Regulator ID REG0119 experimental
Regulator type protein
Regulatory pathway (from literatures) QS regulatory pathway; c-di-GMP regulatory pathway
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00044 experimental (Type i5); T6SS00043 experimental (Type i1)
Strain Vibrio parahaemolyticus RIMD 2210633
Replicon chromosome
Sequence Protein sequence (196 a.a.); Nucleotide sequence (588 bp)
Description TfoX specifically induces T6SS2.; TfoY solely led to T6SS1-mediated prey killing.
Reference
External database links

Locus tag (Gene) VP1241 (TfoX)
Coordinates (Strand) 1309223..1309810 (+)
NCBI ID 28898016
RefSeq NC_004603
Uniprot ID Q87QA8_VIBPA
KEGG ID vpa:VP1241
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
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Target
Regulation (↓/↑)
Target sequence
T6SS2↓-
T6SS1↓-
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Pfam domain hit(s) of regulator

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Domain
Pfam ID
E-value
Aligned region
TfoX_CPF04994.154.1e-28114..192
TfoX_NPF04993.155.8e-2211..101
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Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

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Prediction                
Region    
Sequence
Outside1-195MDMTDQAFFKYVRNFNEYQKRSMFGGIGLFSDDAMFALVSNDCCYLRGGNGLDEEFTLLNCEKYKHVKKQTTATVNYYDVTDLFESGFTGLDDLLRKSIDCSIKERKYQKSSASKRLRDLPNMQLTLERMVKKAGIDDVETFLELGPVEVFNKVRVAYGNDVDVKLLWKFAGAIDGVHWKLIQEPRKKQLLALCE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
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Prediction       
Probability
Cleavage site
Signal peptide sequence
Other0.9766--


  Protein sequence of regulator: 196 a.a.    .

>REG0119 NC_004603:1309223-1309810 [Vibrio parahaemolyticus RIMD 2210633]
MDMTDQAFFKYVRNFNEYQKRSMFGGIGLFSDDAMFALVSNDCCYLRGGNGLDEEFTLLNCEKYKHVKKQTTATVNYYDV
TDLFESGFTGLDDLLRKSIDCSIKERKYQKSSASKRLRDLPNMQLTLERMVKKAGIDDVETFLELGPVEVFNKVRVAYGN
DVDVKLLWKFAGAIDGVHWKLIQEPRKKQLLALCE*

  Nucleotide sequence of regulator: 588 bp    .

>REG0119 NC_004603:1309223-1309810 [Vibrio parahaemolyticus RIMD 2210633]
ATGGACATGACAGACCAAGCTTTTTTTAAATATGTACGCAATTTTAATGAGTATCAGAAACGTTCTATGTTTGGTGGTAT
CGGCTTGTTTAGCGATGACGCCATGTTTGCGCTTGTCAGCAATGATTGCTGTTATTTGCGCGGCGGTAATGGTTTAGACG
AAGAATTTACTCTGCTTAATTGTGAAAAATACAAGCACGTCAAAAAACAGACGACGGCTACTGTAAACTATTATGACGTA
ACCGATTTATTTGAGTCCGGATTTACTGGTCTTGACGATTTGTTACGCAAATCTATTGATTGCTCAATTAAGGAGCGAAA
ATACCAAAAGTCTTCTGCAAGTAAACGTTTGAGAGATCTACCGAACATGCAGCTTACATTAGAGCGCATGGTTAAAAAGG
CGGGTATTGATGATGTTGAAACCTTTTTGGAACTTGGTCCAGTTGAAGTGTTCAACAAAGTAAGAGTTGCTTACGGCAAT
GATGTTGACGTTAAACTGCTGTGGAAGTTTGCTGGTGCCATTGATGGTGTGCACTGGAAACTAATCCAAGAGCCGCGCAA
AAAACAGTTACTGGCACTGTGTGAATAA