SecReT6, T6SS database

Classification of Accessory proteins (T6SAs)

All accessory proteins were experimentally validated.

Experimental investigation has been performed.

Bioinformatics investigation has been performed
All accessory proteins were experimentally validated.

SecReT6 ID	Locus tag (Gene)	Related T6SS	Type	Related structure protein	Related effector	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI
ACP00001	VC1417	T6SS00002	adaptor	VgrG-1	VC1418 (TseL)	Vibrio cholerae O1 biovar El Tor str. N16961	chromosome (NC_002505)	1513748..1514608 (+)	15641428
ACP00002	PA0094 (eagT6)	T6SS00003	adaptor	-	PA0093 (Tse6)	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	114611..115045 (-)	15595292
ACP00005	PA0259 (tla3)	T6SS00004	adaptor	PA0262 (VgrG2b)	PA0260 (Tle3)	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	289562..291004 (-)	15595456
ACP00010	Atu4349 (tap-1)	T6SS00016	adaptor	Atu4348 (VgrG1)	Atu4350 (Tde1)	Agrobacterium fabrum str. C58	chromosome (NC_003063)	1483948..1484904 (+)	737273750
ACP00011	Atu3641	T6SS00016	adaptor	Atu3642 (VgrG2)	Atu3640 (Tde2)	Agrobacterium fabrum str. C58	chromosome (NC_003063)	693818..694927 (-)	499279473
ACP00012	PFL_6095 (eagR1)	T6SS00035	adaptor	-	PFL_6096 (RhsA)	Pseudomonas protegens Pf-5	chromosome (NC_004129)	6924978..6925403 (+)	499376685
ACP00013	PFL_6099 (eagT2)	T6SS00035	adaptor	-	PFL_6209 (Tne2)	Pseudomonas protegens Pf-5	chromosome (NC_004129)	6930853..6931287 (-)	499376689
ACP00024	ECO111_0594 (eagR)	T6SS00367	adaptor	ECO111_0596 (VgrGO1)	ECO111_0594 (Rhs-CT3)	Escherichia coli O111:H- str. 11128	chromosome (NC_013364)	632578..637377 (-)	447211780
ACP00025	VCV52_1391 (tap-1)	T6SS00790	adaptor	VgrG-1	TseL	Vibrio cholerae V52	chromosome (NZ_KQ410498)	434220..435080 (-)	446336115
ACP00026	VCV52_RS01475 (vasW)	T6SS00790	adaptor	-	VasX	Vibrio cholerae V52	chromosome (NZ_KQ410497)	319289..320176 (-)	447180717
ACP00030	SMDB11_1609 (eagR2)	T6SS00929	adaptor	SMDB11_2276 (VgrG2b)	SMDB11_1610 (Rhs2)	Serratia marcescens subsp. marcescens Db11	chromosome (HG326223)	1689187..1689618 (+)	560173452
ACP00031	SMDB11_2245 (eagR1)	T6SS00929	adaptor	SMDB11_2276 (VgrG2b)	SMDB11_2278 (Rhs1)	Serratia marcescens subsp. marcescens Db11	chromosome (HG326223)	2367474..2367863 (+)	560174088
ACP00038	AOM81334 (eagR/DUF1795)	T6SS00941	adaptor	ct1A (VgrGO1)	ct1C (Rhs-CT1)	Escherichia coli strain STEC004	chromosome (KX118288)	1930..2391 (+)	1062685106
ACP00041	A55_1501 (tap-2)	-	adaptor	VgrG-1	TseL	Vibrio cholerae 1587	chromosome (NZ_KQ410627)	235783..236571 (+)	446538621
ACP26818	Plu0354 (EagR)	T6SS00050	adaptor	-	Plu0353 (Tre23)	Photorhabdus laumondii subsp. laumondii TTO1	chromosome (NC_005126)	372357..372677 (-)	WP_011144744.1
ACP44070	BGLU_RS21515	T6SS17510	adaptor	-	-	Burkholderia glumae BGR1	chromosome (NC_012721)	888978..891614 (-)	WP_012733555.1

Experimental investigation has been performed.

Bioinformatics investigation has been performed
All accessory proteins were experimentally validated.

SecReT6 ID	Locus tag (Gene)	Related T6SS	Type	Related structure protein	Related effector	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI
ACP00006	PA3906 (co-TecT)	T6SS00005	chaperone	PA3905 (TecT)	-	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	4374850..4375233 (+)	15599101
ACP00007	PA3905 (tecT)	T6SS00005	chaperone	PA3904 (PAAR4)	PA3907 (TseT)	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	4374330..4374857 (+)	15599100
ACP00008	PA3790 (oprC)	T6SS00005	chaperone	-	PA4922 (Azu)	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	4247703..4249874 (-)	15598985
ACP00014	YPK_0782 (btuB)	T6SS00258	chaperone	-	YPK_0954 (Tce1)	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	1069948..1070205 (+)	488156855
ACP00015	YPK_2649 (ompF)	T6SS00258	chaperone	-	YPK_0954 (Tce1)	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	2911078..2912160 (+)	501261276
ACP00016	YPK_2956 (tonB)	T6SS00258	chaperone	-	YPK_0954 (Tce1)	Yersinia pseudotuberculosis YPIII	chromosome (NC_010465)	3254339..3255631 (-)	488139530
ACP00017	ACIAD_RS12210	T6SS00061	chaperone	-	-	Acinetobacter baylyi ADP1	chromosome (NC_005966)	2641820..2643223 (-)	WP_004928997.1
ACP00018	ACIAD_RS12275	T6SS00061	chaperone	-	peptidoglycan	Acinetobacter baylyi ADP1	chromosome (NC_005966)	2656730..2657683 (+)	WP_026056969.1
ACP00020	FTT_0682c (fipB/dsbA)	T6SS00081	chaperone	FTT_1358c (IglB1); FTT_1357c (IglC1)	-	Francisella tularensis subsp. tularensis SCHU S4	chromosome (NC_006570)	699171..700016 (-)	56707802
ACP00021	BTH_II2139 (hmuR)	T6SS00114	chaperone	-	BTH_II1884 (TseZ)	Burkholderia thailandensis E264	chromosome (NC_007650)	2626542..2628827 (+)	644827063
ACP00022	BTH_RS20365 (mnoT)	T6SS00114	chaperone	-	BTH_II1883 (TseM)	Burkholderia thailandensis E264	chromosome (NC_007651)	1796067..1798403 (+)	497575584
ACP00023	FTN_RS06580 (dnaK)	T6SS00158	chaperone	FTN_RS08950 (ClpB)	-	Francisella tularensis subsp. novicida U112	chromosome (NC_008601)	1356202..1358130 (-)	489130276
ACP00027	BB2000_RS14605 (idsC)	T6SS00838	chaperone	-	BB2000_3005 (IdsD)	Proteus mirabilis BB2000	chromosome (NC_022000)	3278448..3279671 (+)	529249287
ACP00028	SMDB11_4101 (dsbA1)	T6SS00929	chaperone	SMDB11_2255 (TssM); SMDB11_2251; SMDB11_2269	SMDB11_3980 (Ssp4); SMDB11_2264 (Ssp2)	Serratia marcescens subsp. marcescens Db11	chromosome (HG326223)	4377737..4378360 (-)	560175924
ACP00029	SMDB11_0239 (dsbA2)	T6SS00929	chaperone	SMDB11_2255 (TssM); SMDB11_2251; SMDB11_2269	SMDB11_3980 (Ssp4); SMDB11_2264 (Ssp2)	Serratia marcescens subsp. marcescens Db11	chromosome (HG326223)	265001..265642 (+)	560172104
ACP00036	EC042_RS21585 (yidC)	T6SS00931	chaperone	TssL	-	Escherichia coli 042	chromosome (NC_017626)	4320019..4321665 (+)	446300403
ACP00037	EC042_RS00085 (dnaK)	T6SS00931	chaperone	TssL	-	Escherichia coli 042	chromosome (NC_017626)	13600..15516 (+)	446438280
ACP00040	AUO97_13960 (asaA)	T6SS01070	chaperone	AUO97_14000 (TssM)	-	Acinetobacter baumannii strain ATCC 17978	chromosome (NZ_CP018664)	2936023..2936715 (+)	446792453
ACP00043	PA4370 (IcmP)	T6SS00004	chaperone	-	PA1863 (ModA)	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	4898193..4899533 (+)	15599566
ACP00044	PA1862 (ModB)	T6SS00004	chaperone	-	PA1863 (ModA)	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	2021712..2022398 (-)	15597059
ACP00045	PA1861 (ModC)	T6SS00004	chaperone	-	PA1863 (ModA)	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	2020625..2021710 (-)	15597058
ACP26819	HMPREF1171_RS04695 (TecI)	T6SS00788	chaperone	HMPREF1171_RS04690	HMPREF1171_RS04700 (TseI)	Aeromonas dhakensis strain SSU	chromosome (NZ_JH815591)	1021066..1021794 (+)	WP_005299970.1
ACP44068	REUT_RS18795 (cubA)	T6SS17507	chaperone	-	REUT_RS08685 (teoL)	Cupriavidus pinatubonensis JMP134	chromosome (NC_007348)	269098..271227 (-)	WP_041680124.1
ACP44069	REUT_RS23710 (cstR)	T6SS17507	chaperone	-	REUT_RS08685 (teoL)	Cupriavidus pinatubonensis JMP134	chromosome (NC_007348)	1349588..1351858 (+)	WP_041680249.1

Experimental investigation has been performed.

Bioinformatics investigation has been performed
All accessory proteins were experimentally validated.

SecReT6 ID	Locus tag (Gene)	Related T6SS	Type	Related structure protein	Related effector	Organism	Replicon (Accession)	Coordinates (Strand)	Protein GI
ACP00003	PA0086 (tagJ)	T6SS00003	structure affiliated protein	PA0082 (TssA)	-	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	104006..104851 (+)	15595284
ACP00004	PA0086 (tagJ)	T6SS00003	structure affiliated protein	PA0083 (HisB1/TssB1)	-	Pseudomonas aeruginosa PAO1	chromosome (NC_002516)	104006..104851 (+)	15595284
ACP00009	PP_RS16060 (tagB1)	T6SS00014	structure affiliated protein	PP_RS15990 (TssA)	-	Pseudomonas putida KT2440	chromosome (NC_002947)	3496832..3497581 (-)	898330878
ACP00019	FTT_0682c (fipB/dsbA)	T6SS00080	structure affiliated protein	FTT_1713c (IglB2); FTT_1712c (IglC2)	-	Francisella tularensis subsp. tularensis SCHU S4	chromosome (NC_006570)	699171..700016 (-)	56707802
ACP00032	EC042_RS24300 (tagA)	T6SS00931	structure affiliated protein	TssA	-	Escherichia coli 042	chromosome (NC_017626)	4884070..4885437 (+)	446122356
ACP00033	EC042_RS24190 (tagL/ompA)	T6SS00931	structure affiliated protein	TssL	peptidoglycan	Escherichia coli 042	chromosome (NC_017626)	4856944..4858674 (+)	446480629
ACP00034	EC042_1244 (mltE)	T6SS00931	structure affiliated protein	TssM	-	Escherichia coli 042	chromosome (NC_017626)	1322321..1322932 (+)	481024453
ACP00035	EC042_RS24190 (sciZ)	T6SS00931	structure affiliated protein	SciP	peptidoglycan	Escherichia coli 042	chromosome (NC_017626)	4856944..4858674 (+)	446480629
ACP00039	ACX60_11600 (tagX)	T6SS01046	structure affiliated protein	-	peptidoglycan	Acinetobacter baumannii strain ATCC 17978	chromosome (NZ_CP012004)	2432052..2433005 (-)	446895327
ACP44067	VCV52_RS01000 (tagA)	T6SS00790	structure affiliated protein	VCV52_RS01060 (tssE); VCV52_RS01055 (tssF); VCV52_RS01030 (tssL); VCV52_RS01005 (tssM)	VCV52_RS06835 (vgrG1); VCV52_RS00990 (vgrG3); VCV52_RS01485 (hcp-2)	Vibrio cholerae V52	chromosome (NZ_KQ410497)	205313..206575 (-)	WP_000073086.1