Detailed information of effector


Summary

Effector ID EFF01035 experimental
Effector type Tse
Cognate immunity protein IMU00273 experimental
Related T6SS (Type) T6SS00003 experimental (Type i3)
Strain Pseudomonas aeruginosa PAO1
Replicon chromosome
Sequence Protein sequence (431 a.a.); Nucleotide sequence (1293 bp)
Description Tse6
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) PA0093 (Tse6)
Coordinates (Strand) 113303..114595 (-)
NCBI ID 15595291
RefSeq NC_002516
Uniprot ID TSE6_PSEAE
KEGG ID pae:PA0093
PDB ID 4ZV4, 4ZV0, 6OX6, 6XRF
Pfam domain hit(s)

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Domain
Pfam ID
E-value
Aligned region
Ntox46PF15538.83.4e-97266..422
PAAR_motifPF05488.154.2e-1280..151
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Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

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Prediction                
Region    
Sequence
Inside1-12MDAQAAARLGDE
Transmembrane helix13-35IAHGFGVAAMVAGAVAGALIGAA
Outside36-38VVA
Transmembrane helix39-61ATAATGGLAAVILAGSIAAGGLS
Inside62-188MFQIVKGLTTIFELPEPTTGVLIRGSFNVYVNSRNAMRAGDDVSATCSGLPLNHPLWPFPVLIAEGSATVYINGKPAARLQSKMVCGAHIKTGSQNTFIGGPTERVAFVLDLEEWLHTGLEALGLAA
Transmembrane helix189-211LAGGLLLAAMAGVAALVGVVAIG
Outside212-430GLMMGGMALLGDLGDRLGPGYRDLFQGVAGMALLGFGPKLAGRRPAAVTSETAQRRAYLNNKFGRSGNLDHDINYRGNRETAAKFFKSKDIDPADAESYMNGLDFNHPVRVETLAPGKNLWQYQSPGAPQGNWYTLSPRVQPTELGINPMGTNRAANTIEPKVLNSYRTTQKVEVLRSTAAPTDDFWSVKGQSYPAKGGAQQLFSNEKGSFGLLPREGS


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
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Prediction       
Probability
Cleavage site
Signal peptide sequence
Other0.7411--


  Protein sequence: 431 a.a.    .

>EFF01035 NC_002516:c114595-113303 Type VI Secretion System Effector (Tse) [Pseudomonas aeruginosa PAO1]
MDAQAAARLGDEIAHGFGVAAMVAGAVAGALIGAAVVAATAATGGLAAVILAGSIAAGGLSMFQIVKGLTTIFELPEPTT
GVLIRGSFNVYVNSRNAMRAGDDVSATCSGLPLNHPLWPFPVLIAEGSATVYINGKPAARLQSKMVCGAHIKTGSQNTFI
GGPTERVAFVLDLEEWLHTGLEALGLAALAGGLLLAAMAGVAALVGVVAIGGLMMGGMALLGDLGDRLGPGYRDLFQGVA
GMALLGFGPKLAGRRPAAVTSETAQRRAYLNNKFGRSGNLDHDINYRGNRETAAKFFKSKDIDPADAESYMNGLDFNHPV
RVETLAPGKNLWQYQSPGAPQGNWYTLSPRVQPTELGINPMGTNRAANTIEPKVLNSYRTTQKVEVLRSTAAPTDDFWSV
KGQSYPAKGGAQQLFSNEKGSFGLLPREGS*

  Nucleotide sequence: 1293 bp    .

>EFF01035 NC_002516:c114595-113303 Type VI Secretion System Effector (Tse) [Pseudomonas aeruginosa PAO1]
ATGGATGCGCAAGCCGCCGCCCGACTGGGCGATGAGATAGCCCACGGTTTCGGTGTCGCCGCGATGGTCGCCGGAGCCGT
GGCCGGAGCCCTGATCGGCGCCGCCGTGGTCGCCGCCACCGCCGCCACCGGCGGCCTGGCCGCGGTGATCCTGGCCGGTT
CGATCGCCGCCGGCGGGCTGTCGATGTTCCAGATCGTCAAGGGCCTGACCACCATCTTCGAGCTACCCGAGCCGACCACC
GGGGTGCTCATACGCGGCAGCTTCAACGTCTACGTGAACAGTCGCAACGCGATGCGCGCCGGCGACGACGTTTCCGCCAC
CTGCAGCGGCCTGCCGCTGAACCATCCGCTGTGGCCGTTCCCGGTGCTGATCGCCGAAGGCAGCGCGACCGTGTACATCA
ACGGCAAGCCGGCGGCGCGCCTGCAGAGCAAGATGGTCTGCGGCGCGCACATCAAGACCGGCAGCCAGAACACCTTCATC
GGCGGCCCCACCGAGCGGGTGGCCTTCGTCCTCGACCTGGAGGAATGGCTGCACACCGGCCTCGAGGCGCTGGGCCTGGC
GGCCCTAGCCGGCGGCCTGCTGCTGGCGGCGATGGCCGGGGTCGCGGCGCTGGTTGGAGTGGTCGCCATCGGCGGCCTGA
TGATGGGCGGCATGGCCCTGCTCGGCGACCTCGGCGACCGCCTCGGTCCCGGCTACCGCGACCTGTTCCAGGGCGTGGCG
GGGATGGCATTGCTGGGCTTCGGGCCGAAACTCGCCGGTCGTCGTCCGGCAGCGGTGACCTCCGAAACCGCGCAACGACG
CGCCTACCTGAACAACAAGTTCGGTCGTTCCGGCAACCTCGACCACGACATCAACTACCGCGGGAATCGTGAAACCGCCG
CCAAGTTCTTCAAGTCGAAGGACATCGATCCTGCCGATGCCGAGTCGTACATGAACGGCCTGGACTTCAACCATCCGGTC
CGTGTGGAAACCCTCGCGCCCGGCAAGAACCTGTGGCAGTACCAGTCCCCCGGAGCGCCGCAGGGCAACTGGTATACACT
CAGCCCGCGCGTGCAGCCCACGGAGCTGGGAATCAACCCCATGGGCACCAACCGGGCGGCGAACACCATCGAACCCAAGG
TCCTCAACTCCTACAGGACGACCCAGAAGGTCGAGGTCCTGCGCAGCACCGCTGCGCCGACCGATGACTTCTGGTCGGTA
AAGGGACAGTCATATCCCGCCAAAGGCGGCGCGCAACAACTGTTCTCCAACGAGAAAGGCTCCTTCGGTCTGCTTCCCCG
GGAGGGATCATGA