Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00367  |
| T6SS type | Type i1 |
| Strain | Escherichia coli O111:H- str. 11128 |
| Replicon (RefSeq) | chromosome (NC_013364) |
| Location | 241320..264830 |
| Function | - |
| Comment | - |
| References | - |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | PAAR | TssA | TssB | TssC | TssD | TssE | TssF | TssH | TssI | TssJ | TssK | TssL |
| Number | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| ECO111_RS01100 (yafS) | 236476..237198 | + | 723 | WP_001326291.1 | class I SAM-dependent methyltransferase | ||
| ECO111_RS01105 (rnhA) | 237195..237662 | - | 468 | WP_000917883.1 | ribonuclease HI | ||
| ECO111_RS01110 (dnaQ) | 237727..238458 | + | 732 | WP_001297205.1 | DNA polymerase III subunit epsilon | ||
| ECO111_RS01120 | 238998..239736 | + | 739 | pseudogene | hypothetical protein | ||
| ECO111_RS01125 | 239873..240352 | - | 480 | WP_001236640.1 | hypothetical protein | ||
| ECO111_RS01130 | 240362..241276 | - | 915 | WP_000908052.1 | hypothetical protein | ||
| T6CP008830 | TssD | ECO111_RS01135 | 241320..241802 | - | 483 | WP_001284199.1 | Hcp family type VI secretion system effector |
| T6CP008831 | TssA | ECO111_RS01140 | 241826..243178 | - | 1353 | WP_001087754.1 | type VI secretion system ImpA and VasL domain-containing protein |
| ECO111_RS01145 (tssM) | 243189..246622 | - | 3434 | pseudogene | type VI secretion system membrane subunit TssM | ||
| T6CP008832 | TssA | ECO111_RS01150 (tssA) | 246731..248143 | - | 1413 | WP_001240529.1 | type VI secretion system protein TssA |
| ECO111_RS01155 (tagO) | 248148..248891 | - | 744 | WP_000088862.1 | type VI secretion system-associated protein TagO | ||
| T6CP003751 | TssH | ECO111_RS01160 (tssH) | 248888..251725 | - | 2838 | WP_000614365.1 | type VI secretion system ATPase TssH |
| T6CP003752 | TssL | ECO111_RS01165 (icmH) | 251734..252495 | - | 762 | WP_000343299.1 | type IVB secretion system protein IcmH/DotU |
| T6CP003753 | TssK | ECO111_RS01170 (tssK) | 252500..253831 | - | 1332 | WP_000246429.1 | type VI secretion system baseplate subunit TssK |
| T6CP003754 | TssJ | ECO111_RS01175 (tssJ) | 253834..254358 | - | 525 | WP_001080149.1 | type VI secretion system lipoprotein TssJ |
| T6CP011788 | FHA | ECO111_RS01180 (tagH) | 254355..255635 | - | 1281 | WP_001113729.1 | type VI secretion system-associated FHA domain protein TagH |
| ECO111_RS01185 (tssG) | 255660..256741 | - | 1082 | pseudogene | type VI secretion system baseplate subunit TssG | ||
| T6CP003755 | TssF | ECO111_RS01190 (tssF) | 256705..258555 | - | 1851 | WP_000393860.1 | type VI secretion system baseplate subunit TssF |
| T6CP008833 | TssE | ECO111_RS01195 (tssE) | 258559..258972 | - | 414 | WP_000611742.1 | type VI secretion system baseplate subunit TssE |
| T6CP003756 | TssC | ECO111_RS01200 (tssC) | 258979..260454 | - | 1476 | WP_000056978.1 | type VI secretion system contractile sheath large subunit |
| T6CP008834 | TssC | ECO111_RS01205 | 260505..260729 | - | 225 | WP_000123970.1 | hypothetical protein |
| T6CP003757 | TssB | ECO111_RS01210 (tssB) | 260764..261264 | - | 501 | WP_000037389.1 | type VI secretion system contractile sheath small subunit |
| T6CP008835 | TssD | ECO111_RS01220 | 261961..262479 | + | 519 | WP_001142958.1 | Hcp family type VI secretion system effector |
| T6CP003758 | TssI | ECO111_RS01230 | 262689..264830 | + | 2142 | WP_000103324.1 | type VI secretion system tip protein VgrG |
| T6CP011789 | PAAR | ECO111_RS01235 | 264906..269135 | + | 4230 | WP_000509079.1 | RHS repeat protein |
| ECO111_RS01240 | 269119..269601 | + | 483 | WP_000939263.1 | hypothetical protein | ||
| ECO111_RS33555 | 269516..269701 | - | 186 | WP_122985282.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00342 |
ECO111_0593 (CTI3) | EFF01519 |
Escherichia coli O111:H- str. 11128 | chromosome (NC_013364) | 632211..632576 (-) | 446014673 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| ACP00024 |
ECO111_0594 (eagR) | adaptor | Escherichia coli O111:H- str. 11128 | chromosome (NC_013364) | 632578..637377 (-) | 447211780 | ECO111_0596 (VgrGO1) | ECO111_0594 (Rhs-CT3) |