Detailed information of effector
Summary
| Effector ID | EFF01874  |
| Effector type | Tde |
| Cognate immunity protein | IMU00376 |
| Related T6SS (Type) | T6SS00258 (Type i3) |
| Strain | Yersinia pseudotuberculosis YPIII |
| Replicon | chromosome |
| Sequence | Protein sequence (86 a.a.); Nucleotide sequence (258 bp) |
| Description | Tce1 exhibits Ca2+,Mg2+-dependent DNase activity and mediates contact-independent T6SS killing |
| Reference |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | YPK_0954 (Tce1) |
| Coordinates (Strand) | 1069948..1070205 (+) |
| NCBI ID | 488156855 |
| RefSeq | NC_010465 |
| Uniprot ID | Q666X9_YERPS |
| KEGG ID | yps:YPTB3115 |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-85 | MVANGNVESISLPEVRRLMSGELDRSSASEWAFAIIDDDHIRVSDQVVWKVLQCLGGADLPITDREYLYEKEDFNCWLNEIDSHE |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9928 | - | - |
Protein sequence: 86 a.a. .
>EFF01874 NC_010465:1069948-1070205 Type VI DNase and RNase Effector (Tde) [Yersinia pseudotuberculosis YPIII]
MVANGNVESISLPEVRRLMSGELDRSSASEWAFAIIDDDHIRVSDQVVWKVLQCLGGADLPITDREYLYEKEDFNCWLNE
IDSHE*
MVANGNVESISLPEVRRLMSGELDRSSASEWAFAIIDDDHIRVSDQVVWKVLQCLGGADLPITDREYLYEKEDFNCWLNE
IDSHE*
Nucleotide sequence: 258 bp .
>EFF01874 NC_010465:1069948-1070205 Type VI DNase and RNase Effector (Tde) [Yersinia pseudotuberculosis YPIII]
ATGGTAGCAAATGGTAACGTTGAGAGCATTTCACTGCCGGAGGTAAGGCGCTTAATGTCAGGGGAACTTGACCGCTCAAG
CGCCTCTGAATGGGCGTTTGCAATAATTGATGATGATCACATTCGAGTAAGCGATCAGGTTGTTTGGAAAGTACTTCAAT
GCTTGGGGGGAGCAGATTTACCGATAACTGACAGGGAGTATTTATATGAAAAAGAAGACTTTAATTGCTGGCTCAACGAA
ATTGACTCACATGAGTAA
ATGGTAGCAAATGGTAACGTTGAGAGCATTTCACTGCCGGAGGTAAGGCGCTTAATGTCAGGGGAACTTGACCGCTCAAG
CGCCTCTGAATGGGCGTTTGCAATAATTGATGATGATCACATTCGAGTAAGCGATCAGGTTGTTTGGAAAGTACTTCAAT
GCTTGGGGGGAGCAGATTTACCGATAACTGACAGGGAGTATTTATATGAAAAAGAAGACTTTAATTGCTGGCTCAACGAA
ATTGACTCACATGAGTAA