Detailed information of effector
Summary
| Effector ID | EFF76648  |
| Effector type | - |
| Cognate immunity protein | - |
| Related T6SS (Type) | T6SS17507 (Type i4a) |
| Strain | Cupriavidus pinatubonensis JMP134 |
| Replicon | chromosome |
| Sequence | Protein sequence (208 a.a.); Nucleotide sequence (624 bp) |
| Description | TeoL is an effector protein mainly secreted by T6SS1 and contributes to acquisition of iron from OMVs. TeoL recruits OMVs through binding LPS. During OMV recruitment, the role of TeoL is to tether iron-containing OMVs to specific receptors on the cell surface. |
| Reference |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | REUT_RS08685 (teoL) |
| Coordinates (Strand) | 1862145..1862768 (-) |
| NCBI ID | WP_140950547.1 |
| RefSeq | NC_007347 |
| Uniprot ID | UPI00112D922A |
| KEGG ID | - |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-207 | MLSRCSVADGLPHGRMERFAPDGTRLLEANYVAGKLSGWLRNYDAAGEPVLASHYAGGLLHGPSESYQQGRLACREHYVNGVLEGERSCYGPAGELVAQAVFRRGLLEGEAIWLHEGVVVRRSRFRAGKLEGETRSYAADGTLTLSEPFRADLLHGTARRFDEAGRVSWQRDYTDGKPRGQWRAAAATDNGAAAPSFSQRLERWVRG |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9739 | - | - |
Protein sequence: 208 a.a. .
>EFF76648 NC_007347:c1862768-1862145 (Unknown) [Cupriavidus pinatubonensis JMP134]
MLSRCSVADGLPHGRMERFAPDGTRLLEANYVAGKLSGWLRNYDAAGEPVLASHYAGGLLHGPSESYQQGRLACREHYVN
GVLEGERSCYGPAGELVAQAVFRRGLLEGEAIWLHEGVVVRRSRFRAGKLEGETRSYAADGTLTLSEPFRADLLHGTARR
FDEAGRVSWQRDYTDGKPRGQWRAAAATDNGAAAPSFSQRLERWVRG*
MLSRCSVADGLPHGRMERFAPDGTRLLEANYVAGKLSGWLRNYDAAGEPVLASHYAGGLLHGPSESYQQGRLACREHYVN
GVLEGERSCYGPAGELVAQAVFRRGLLEGEAIWLHEGVVVRRSRFRAGKLEGETRSYAADGTLTLSEPFRADLLHGTARR
FDEAGRVSWQRDYTDGKPRGQWRAAAATDNGAAAPSFSQRLERWVRG*
Nucleotide sequence: 624 bp .
>EFF76648 NC_007347:c1862768-1862145 (Unknown) [Cupriavidus pinatubonensis JMP134]
CTGCTGTCGCGCTGTAGCGTGGCCGACGGGCTGCCGCACGGCCGCATGGAGCGCTTCGCCCCGGACGGTACGCGGCTGCT
GGAAGCCAACTATGTAGCGGGCAAGCTGTCGGGCTGGCTGCGCAACTATGACGCGGCCGGCGAGCCGGTGCTGGCTTCGC
ACTATGCCGGCGGCCTGCTCCACGGTCCCAGCGAAAGCTACCAGCAAGGCCGTCTGGCCTGCCGCGAGCACTACGTGAAC
GGCGTGCTCGAAGGCGAGCGCAGCTGCTATGGGCCTGCGGGCGAACTCGTGGCGCAGGCAGTGTTTCGCCGGGGCCTGCT
CGAGGGCGAAGCGATCTGGCTGCACGAAGGCGTGGTGGTGCGGCGCAGCCGCTTCCGTGCCGGCAAGCTGGAGGGCGAGA
CCCGCAGCTATGCGGCGGACGGGACCCTGACGCTGTCCGAGCCCTTTCGCGCCGACCTGCTGCATGGCACCGCACGCCGC
TTCGACGAGGCCGGCCGTGTCAGCTGGCAGCGCGACTACACCGATGGCAAGCCGCGCGGCCAATGGCGCGCTGCGGCCGC
GACCGACAATGGCGCCGCCGCGCCGAGTTTTTCCCAACGCCTCGAGCGCTGGGTCAGGGGCTGA
CTGCTGTCGCGCTGTAGCGTGGCCGACGGGCTGCCGCACGGCCGCATGGAGCGCTTCGCCCCGGACGGTACGCGGCTGCT
GGAAGCCAACTATGTAGCGGGCAAGCTGTCGGGCTGGCTGCGCAACTATGACGCGGCCGGCGAGCCGGTGCTGGCTTCGC
ACTATGCCGGCGGCCTGCTCCACGGTCCCAGCGAAAGCTACCAGCAAGGCCGTCTGGCCTGCCGCGAGCACTACGTGAAC
GGCGTGCTCGAAGGCGAGCGCAGCTGCTATGGGCCTGCGGGCGAACTCGTGGCGCAGGCAGTGTTTCGCCGGGGCCTGCT
CGAGGGCGAAGCGATCTGGCTGCACGAAGGCGTGGTGGTGCGGCGCAGCCGCTTCCGTGCCGGCAAGCTGGAGGGCGAGA
CCCGCAGCTATGCGGCGGACGGGACCCTGACGCTGTCCGAGCCCTTTCGCGCCGACCTGCTGCATGGCACCGCACGCCGC
TTCGACGAGGCCGGCCGTGTCAGCTGGCAGCGCGACTACACCGATGGCAAGCCGCGCGGCCAATGGCGCGCTGCGGCCGC
GACCGACAATGGCGCCGCCGCGCCGAGTTTTTCCCAACGCCTCGAGCGCTGGGTCAGGGGCTGA