Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


T6SS ID T6SS00061 experimental
T6SS type Type i4b
Strain Acinetobacter sp. ADP1
Replicon (RefSeq) chromosome (NC_005966)
Location 2633143..2661510
Function effector translocation
Comment -
[1] Weber BS et al (2013) Genomic and Functional Analysis of the Type VI Secretion System in Acinetobacter. PLoS One. 8(1):e55142. [PudMed:23365692]
[2] Shneider MM et al (2013) PAAR-repeat proteins sharpen and diversify the type VI secretion system spike. Nature. 500(7462):350-3. [PudMed:23925114]
[3] Basler M et al (2013) Tit-for-Tat: Type VI Secretion System Counterattack during Bacterial Cell-Cell Interactions. Cell. 152(4):884-94. [PudMed:23415234]
[4] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
ACIAD_RS12160 2628937..2629467 - 531 WP_026056971.1 flavin reductase family protein
ACIAD_RS12165 2629502..2630740 - 1239 WP_004928964.1 hypothetical protein
ACIAD_RS12170 2630795..2631586 - 792 WP_004928967.1 SDR family oxidoreductase
ACIAD_RS12175 2631616..2632863 - 1248 WP_004928970.1 dienelactone hydrolase family protein
ACIAD_RS12180 2633143..2634144 - 1002 WP_004928972.1 AraC family transcriptional regulator
ACIAD_RS12185 2634401..2635675 - 1275 WP_171056930.1 Glu/Leu/Phe/Val dehydrogenase
T6CP011380 PAAR ACIAD_RS12190 2635901..2636167 - 267 WP_004928977.1 PAAR domain-containing protein
T6CP011379 TagL ACIAD_RS12195 2636197..2636961 - 765 WP_004928979.1 OmpA family protein
ACIAD_RS12200 (tagF) 2636964..2637923 - 960 WP_004928987.1 type VI secretion system-associated protein TagF
T6CP000520 TssM ACIAD_RS12205 (tssM) 2637964..2641785 - 3822 WP_004928993.1 type VI secretion system membrane subunit TssM
ACIAD_RS12210 2641820..2643223 - 1404 WP_004928997.1 hypothetical protein
T6CP000521 TssG ACIAD_RS12215 (tssG) 2643220..2644218 - 999 WP_004928999.1 type VI secretion system baseplate subunit TssG
T6CP000522 TssF ACIAD_RS12220 (tssF) 2644182..2645990 - 1809 WP_004929001.1 type VI secretion system baseplate subunit TssF
T6CP000523 TssE ACIAD_RS12225 (tssE) 2646002..2646475 - 474 WP_004929004.1 type VI secretion system baseplate subunit TssE
T6CP000524 TssD ACIAD_RS12230 2646545..2647048 - 504 WP_004929007.1 type VI secretion system tube protein Hcp
T6CP000525 TssC ACIAD_RS12235 (tssC) 2647094..2648575 - 1482 WP_004929011.1 type VI secretion system contractile sheath large subunit
T6CP000526 TssB ACIAD_RS12240 (tssB) 2648568..2649071 - 504 WP_004929014.1 type VI secretion system contractile sheath small subunit
ACIAD_RS12245 2649091..2649747 - 657 WP_004929016.1 hypothetical protein
T6CP000527 TssH ACIAD_RS12250 (tssH) 2650134..2652809 + 2676 WP_100222860.1 type VI secretion system ATPase TssH
T6CP000528 TssA ACIAD_RS12255 (tssA) 2652825..2653928 + 1104 WP_004929021.1 type VI secretion system protein TssA
T6CP000529 TssK ACIAD_RS12260 (tssK) 2653945..2655312 + 1368 WP_004929024.1 type VI secretion system baseplate subunit TssK
T6CP000530 TssL ACIAD_RS12265 2655324..2656127 + 804 WP_004929028.1 type IVB secretion system protein IcmH/DotU
ACIAD_RS12270 2656138..2656719 + 582 WP_004929031.1 hypothetical protein
ACIAD_RS12275 2656730..2657683 + 954 WP_026056969.1 M15 family metallopeptidase
ACIAD_RS12280 (prpF) 2657701..2658882 - 1182 WP_004929035.1 2-methylaconitate cis-trans isomerase PrpF
ACIAD_RS12285 2659669..2660025 + 357 WP_004929038.1 hypothetical protein
ACIAD_RS12290 2660030..2660530 + 501 WP_004929041.1 hypothetical protein
ACIAD_RS12295 2660893..2661510 + 618 WP_004929047.1 hypothetical protein
ACIAD_RS12300 2661512..2661904 + 393 WP_004929049.1 hypothetical protein
ACIAD_RS12305 2662359..2663201 + 843 WP_004929052.1 hypothetical protein
ACIAD_RS12310 2663226..2663423 + 198 WP_011182593.1 hypothetical protein
ACIAD_RS12315 2663658..2664314 + 657 WP_004929058.1 hypothetical protein
ACIAD_RS12325 2664856..2665167 + 312 WP_004929065.1 hypothetical protein
ACIAD_RS12330 2665176..2665442 + 267 WP_011182594.1 hypothetical protein
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files


Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector
ACP00017 experimental ACIAD_RS12210 chaperone Acinetobacter baylyi ADP1 chromosome (NC_005966) 2641820..2643223 (-) WP_004928997.1 - -
ACP00018 experimental ACIAD_RS12275 chaperone Acinetobacter baylyi ADP1 chromosome (NC_005966) 2656730..2657683 (+) WP_026056969.1 - peptidoglycan