Detailed information of accessory protein


Summary

Accessory protein ID ACP00006 experimental
Type chaperone
Related T6SS (Type) T6SS00005 (Type i4a)
Strain Pseudomonas aeruginosa PAO1
Replicon chromosome
Related structure protein PA3905 (TecT)
Related effector -
Description co-TecT
Reference [1] Burkinshaw BJ, Liang X, Wong M, et al. A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone complex. Nat Microbiol. 2018 May;3(5):632-640. doi: 10.1038/s41564-018-0144-4. Epub 2018 Apr 9. PMID: 29632369
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed

External database links

Locus tag (Gene) PA3906 (co-TecT)
Coordinates (Strand) 4374850..4375233 (+)
NCBI ID 15599101
RefSeq NC_002516
Uniprot ID Q9HXA7_PSEAE
KEGG ID pae:PA3906
PDB ID -

Pfam domain hit(s)

Domain Pfam ID E-value Aligned region

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-127 MLELDAGQLDRLQRVRDDEVIERVLLEVRREAPAWLERRGLLPAIRQLGELRATALELGIEEPGTIERFLLHGLAFPAFQDTPAFLAHMRRPLADSPEQRFQDYERIVEFRLASQKWRAYETSGRPA



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9815 - -



  Protein sequence: 128 a.a.    

>ACP00006 NC_002516:4374850-4375233 [Pseudomonas aeruginosa PAO1]
MLELDAGQLDRLQRVRDDEVIERVLLEVRREAPAWLERRGLLPAIRQLGELRATALELGIEEPGTIERFLLHGLAFPAFQ
DTPAFLAHMRRPLADSPEQRFQDYERIVEFRLASQKWRAYETSGRPA*

  Nucleotide sequence: 384 bp    

>ACP00006 NC_002516:4374850-4375233 [Pseudomonas aeruginosa PAO1]
ATGCTTGAACTGGATGCCGGCCAACTGGATCGCCTGCAGCGGGTCCGCGACGACGAAGTCATCGAGCGGGTCCTGCTGGA
GGTACGCCGGGAGGCTCCCGCCTGGCTCGAACGACGCGGCCTGCTGCCCGCCATCCGGCAACTCGGCGAGCTGCGCGCGA
CGGCGCTGGAACTGGGTATCGAAGAGCCCGGGACGATCGAACGCTTTCTTCTGCACGGCCTGGCCTTCCCCGCTTTCCAG
GACACGCCGGCGTTTCTCGCACACATGCGCCGGCCGCTGGCGGACAGCCCGGAACAACGCTTCCAGGACTACGAACGGAT
CGTCGAGTTTCGCCTGGCCAGCCAGAAATGGCGCGCGTACGAAACCTCGGGGAGACCGGCATGA