Detailed information of accessory protein


Summary

Accessory protein ID ACP00007 experimental
Type chaperone
Related T6SS (Type) T6SS00005 (Type i4a)
Strain Pseudomonas aeruginosa PAO1
Replicon chromosome
Related structure protein PA3904 (PAAR4)
Related effector PA3907 (TseT)
Description TecT
Reference [1] Burkinshaw BJ, Liang X, Wong M, et al. A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone complex. Nat Microbiol. 2018 May;3(5):632-640. doi: 10.1038/s41564-018-0144-4. Epub 2018 Apr 9. PMID: 29632369
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed

External database links

Locus tag (Gene) PA3905 (tecT)
Coordinates (Strand) 4374330..4374857 (+)
NCBI ID 15599100
RefSeq NC_002516
Uniprot ID Q9HXA8_PSEAE
KEGG ID pae:PA3905
PDB ID -

Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
DUF4123 PF13503.8 2e-26 17..144

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-175 VSRLQPALAAPTPDSRLFALADGARYLTLDTRLEKAAGEIRSRWLLAGSELDEIAHAGPVLIEFMDSAPLSSSGEFLGWLRDWDRRSPMASWLWSRASFENLAKHFAGLLFTRMPDGRRALLRYYSPEVRRALEQVMTARQWTQVMAPLERWQVWQPLQGGYLVYDRETERTADA



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9718 - -



  Protein sequence: 176 a.a.    

>ACP00007 NC_002516:4374330-4374857 [Pseudomonas aeruginosa PAO1]
VSRLQPALAAPTPDSRLFALADGARYLTLDTRLEKAAGEIRSRWLLAGSELDEIAHAGPVLIEFMDSAPLSSSGEFLGWL
RDWDRRSPMASWLWSRASFENLAKHFAGLLFTRMPDGRRALLRYYSPEVRRALEQVMTARQWTQVMAPLERWQVWQPLQG
GYLVYDRETERTADA*

  Nucleotide sequence: 528 bp    

>ACP00007 NC_002516:4374330-4374857 [Pseudomonas aeruginosa PAO1]
GTGAGCCGGCTCCAGCCGGCGCTCGCGGCGCCTACGCCGGACAGCCGCCTGTTCGCCCTGGCGGACGGCGCCCGCTACCT
GACCCTGGACACCCGCCTGGAAAAGGCCGCGGGGGAAATCCGCTCGCGCTGGCTGCTGGCCGGGAGCGAGCTGGACGAAA
TCGCCCATGCCGGGCCGGTCCTGATCGAATTCATGGACAGCGCCCCGCTTTCGTCATCGGGCGAGTTCCTCGGCTGGCTG
CGCGACTGGGACCGCCGCTCGCCCATGGCCTCCTGGCTGTGGAGCCGGGCGTCCTTCGAAAACCTCGCGAAACACTTCGC
CGGGCTGCTCTTCACCCGCATGCCCGACGGCCGCCGGGCGCTGTTGCGCTACTACAGCCCGGAAGTGCGCCGGGCGCTGG
AACAGGTCATGACCGCGCGGCAATGGACGCAAGTGATGGCGCCGCTGGAGCGTTGGCAGGTCTGGCAGCCCCTGCAGGGC
GGCTACCTCGTCTATGACCGGGAAACGGAGCGGACCGCCGATGCTTGA