Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00941 experimental
T6SS type Type Unknown
Strain Escherichia coli strain STEC004
Replicon (GenBank) chromosome I (KX118288)
Location 1..7947
Function anti-bacterial
Comment E. coli STEC004 cells deploy Rhs-CT1 to inhibit neighboring cells and protect themselves with the corresponding immunity protein CTI1.
References
[1] Ma J, Sun M, Dong W, Pan Z, Lu C, Yao H et al (2017) PAAR-Rhs proteins harbor various C-terminal toxins to diversify the antibacterial pathways of type VI secretion systems. Environ Microbiol. (1):345-360. [PudMed:27871130]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentCt1ACt1BCt1CCt1DCt1E
Number11111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
T6CP016141 Ct1A Locus_01 (ct1A) 1..1902 + 1902 1062685105 orphan Vgr family protein
T6CP016142 Ct1B Locus_02 (ct1B) 1930..2391 + 462 1062685106 DUF1795 protein
T6CP016143 Ct1C Locus_03 (ct1C) 2411..7273 + 4863 1062685107 Rhs core protein
T6CP016144 Ct1D Locus_04 (ct1D) 7270..7521 + 252 1062685108 immunity protein of metallopeptidase 4 toxin
T6CP016145 Ct1E Locus_05 (ct1E) 7636..7947 + 312 1062685109 hypothetical protein
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID
EFF01518 experimental ct1C (Rhs-CT1) Tpe IMU00321 experimental Escherichia coli strain STEC004 chromosome (KX118288) 2411..7273 (+) 1062685107

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID
IMU00321 experimental AOM81336 (CTI1) EFF01518 experimental Escherichia coli strain STEC004 chromosome (KX118288) 7270..7521 (+) 1062685108

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector
ACP00038 experimental AOM81334 (eagR/DUF1795) adaptor Escherichia coli strain STEC004 chromosome (KX118288) 1930..2391 (+) 1062685106 ct1A (VgrGO1) ct1C (Rhs-CT1)