Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01250  |
| T6SS type | Type i5 |
| Strain | Vibrio parahaemolyticus strain D4 |
| Replicon (RefSeq) | chromosome (NZ_NNJE01000049) |
| Location | 1..20649 |
| Function | anti-bacterial |
| Comment | T6SS can secrete hcp at 27°C, T6SS1 can secrete VGRG and show bactericidal activity. |
| References | [1] Li P, Kinch LN, Ray A, Dalia AB, Cong Q, Nunan LM, Camilli A, Grishin NV, Salomon D, Orth K. et al (2017) Acute Hepatopancreatic Necrosis Disease-Causing Vibrio parahaemolyticus Strains Maintain an Antibacterial Type VI Secretion System with Versatile Effector Repertoires.. Appl Environ Microbiol. 83(13). [PudMed:28432099] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagF | TagH | TssA | TssB | TssC | TssE | TssF | TssG | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| CGI87_RS17145 (tssH) | 1..2529 | - | 2529 | 1693555026 | type VI secretion system ATPase TssH | ||
| T6CP015661 | TssG | CGI87_RS17150 (tssG) | 2540..3505 | - | 966 | 526016834 | type VI secretion system baseplate subunit TssG |
| T6CP015662 | TssF | CGI87_RS17155 (tssF) | 3502..5325 | - | 1824 | 526016835 | type VI secretion system baseplate subunit TssF |
| T6CP015663 | TssE | CGI87_RS17160 (tssE) | 5322..5786 | - | 465 | 505126202 | type VI secretion system baseplate subunit TssE |
| CGI87_RS17165 | 5795..6592 | - | 798 | 526016837 | protein of avirulence locus ImpE | ||
| T6CP015664 | TssC | CGI87_RS17170 (tssC) | 6603..8114 | - | 1512 | 646367867 | type VI secretion system contractile sheath large subunit |
| T6CP015665 | TssC | CGI87_RS17175 (tssC) | 8170..9663 | - | 1494 | 491606251 | type VI secretion system contractile sheath large subunit |
| T6CP015666 | TssB | CGI87_RS17180 (tssB) | 9663..10193 | - | 531 | 491606249 | type VI secretion system contractile sheath small subunit |
| T6CP015667 | TssA | CGI87_RS17185 (tssA) | 10209..11330 | - | 1122 | 491622789 | type VI secretion system protein TssA |
| CGI87_RS17190 | 11327..12115 | - | 789 | 491606245 | serine/threonine-protein phosphatase | ||
| T6CP015668 | TagF | CGI87_RS17195 (tagF) | 12126..12821 | - | 696 | 491641506 | type VI secretion system-associated protein TagF |
| T6CP015669 | TssM | CGI87_RS17200 (tssM) | 12803..16321 | - | 3519 | 526016841 | type VI secretion system membrane subunit TssM |
| T6CP015670 | TssL | CGI87_RS17205 (tssL) | 16337..17629 | - | 1293 | 491641512 | type VI secretion system protein TssL, long form |
| T6CP015671 | TssK | CGI87_RS17210 (tssK) | 17641..18966 | - | 1326 | 491606237 | type VI secretion system baseplate subunit TssK |
| T6CP015672 | TssJ | CGI87_RS17215 (tssJ) | 18988..19443 | - | 456 | 491606235 | type VI secretion system lipoprotein TssJ |
| T6CP015673 | TagH | CGI87_RS17220 (tagH) | 19453..20649 | - | 1197 | 491606233 | type VI secretion system-associated FHA domain protein TagH |
| CGI87_RS17225 | 20972..23113 | + | 2142 | 526016846 | serine/threonine protein kinase | ||
| CGI87_RS17230 | 23225..24760 | + | 1536 | 526016848 | response regulator | ||
| CGI87_RS17235 | 24763..25098 | + | 336 | 526016850 | hypothetical protein | ||
| CGI87_RS27460 | 25134..25325 | + | 192 | 526016852 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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