Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS01250 experimental
T6SS type Type i5
Strain Vibrio parahaemolyticus strain D4
Replicon (RefSeq) chromosome (NZ_NNJE01000049)
Location 1..20649
Function anti-bacterial
Comment T6SS can secrete hcp at 27°C, T6SS1 can secrete VGRG and show bactericidal activity.
References
[1] Li P, Kinch LN, Ray A, Dalia AB, Cong Q, Nunan LM, Camilli A, Grishin NV, Salomon D, Orth K. et al (2017) Acute Hepatopancreatic Necrosis Disease-Causing Vibrio parahaemolyticus Strains Maintain an Antibacterial Type VI Secretion System with Versatile Effector Repertoires.. Appl Environ Microbiol. 83(13). [PudMed:28432099]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentTagFTagHTssATssBTssCTssETssFTssGTssJTssKTssLTssM
Number111121111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
CGI87_RS17145 (tssH) 1..2529 - 2529 1693555026 type VI secretion system ATPase TssH
T6CP015661 TssG CGI87_RS17150 (tssG) 2540..3505 - 966 526016834 type VI secretion system baseplate subunit TssG
T6CP015662 TssF CGI87_RS17155 (tssF) 3502..5325 - 1824 526016835 type VI secretion system baseplate subunit TssF
T6CP015663 TssE CGI87_RS17160 (tssE) 5322..5786 - 465 505126202 type VI secretion system baseplate subunit TssE
CGI87_RS17165 5795..6592 - 798 526016837 protein of avirulence locus ImpE
T6CP015664 TssC CGI87_RS17170 (tssC) 6603..8114 - 1512 646367867 type VI secretion system contractile sheath large subunit
T6CP015665 TssC CGI87_RS17175 (tssC) 8170..9663 - 1494 491606251 type VI secretion system contractile sheath large subunit
T6CP015666 TssB CGI87_RS17180 (tssB) 9663..10193 - 531 491606249 type VI secretion system contractile sheath small subunit
T6CP015667 TssA CGI87_RS17185 (tssA) 10209..11330 - 1122 491622789 type VI secretion system protein TssA
CGI87_RS17190 11327..12115 - 789 491606245 serine/threonine-protein phosphatase
T6CP015668 TagF CGI87_RS17195 (tagF) 12126..12821 - 696 491641506 type VI secretion system-associated protein TagF
T6CP015669 TssM CGI87_RS17200 (tssM) 12803..16321 - 3519 526016841 type VI secretion system membrane subunit TssM
T6CP015670 TssL CGI87_RS17205 (tssL) 16337..17629 - 1293 491641512 type VI secretion system protein TssL, long form
T6CP015671 TssK CGI87_RS17210 (tssK) 17641..18966 - 1326 491606237 type VI secretion system baseplate subunit TssK
T6CP015672 TssJ CGI87_RS17215 (tssJ) 18988..19443 - 456 491606235 type VI secretion system lipoprotein TssJ
T6CP015673 TagH CGI87_RS17220 (tagH) 19453..20649 - 1197 491606233 type VI secretion system-associated FHA domain protein TagH
CGI87_RS17225 20972..23113 + 2142 526016846 serine/threonine protein kinase
CGI87_RS17230 23225..24760 + 1536 526016848 response regulator
CGI87_RS17235 24763..25098 + 336 526016850 hypothetical protein
CGI87_RS27460 25134..25325 + 192 526016852 hypothetical protein
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector