Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01088  |
| T6SS type | Type i1 |
| Strain | Vibrio anguillarum strain MHK3 |
| Replicon (RefSeq) | chromosome (NZ_CP022469) |
| Location | 244348..263491 |
| Function | anti-bacterial |
| Comment | MHK3 was shown to constitutively express, secrete Hcp and showed a T6SS-dependent antibacterial function. |
| References | [1] Tang L, Yue S, Li GY, Li J, Wang XR, Li SF, Mo ZL. et al (2016) Expression, secretion and bactericidal activity of type VI secretion system in Vibrio anguillarum.. Arch Microbiol. 198(8):751-60. [PudMed:27172981] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| CG015_RS14305 (tssI) | 239355..242827 | - | 3473 | pseudogene | type VI secretion system tip protein VgrG | ||
| CG015_RS14310 | 242995..244290 | - | 1296 | WP_017046811.1 | type VI secretion system ImpA family N-terminal domain-containing protein | ||
| T6CP014001 | TssM | CG015_RS14315 (tssM) | 244348..247848 | - | 3501 | WP_026028432.1 | type VI secretion system membrane subunit TssM |
| T6CP014002 | TssA | CG015_RS14320 (tssA) | 247911..249308 | - | 1398 | WP_017046812.1 | type VI secretion system protein TssA |
| CG015_RS14325 (tagO) | 249318..249938 | - | 621 | WP_197540122.1 | type VI secretion system-associated protein TagO | ||
| CG015_RS14330 | 249974..251536 | - | 1563 | WP_026027749.1 | sigma-54-dependent Fis family transcriptional regulator | ||
| T6CP014003 | TssH | CG015_RS14335 (tssH) | 251539..254157 | - | 2619 | WP_029189701.1 | type VI secretion system ATPase TssH |
| T6CP014004 | TssL | CG015_RS14340 (icmH) | 254181..254954 | - | 774 | WP_026027751.1 | type IVB secretion system protein IcmH/DotU |
| T6CP014005 | TssK | CG015_RS14345 (tssK) | 254957..256291 | - | 1335 | WP_017044997.1 | type VI secretion system baseplate subunit TssK |
| T6CP014006 | TssJ | CG015_RS14350 (tssJ) | 256296..256775 | - | 480 | WP_013868298.1 | type VI secretion system lipoprotein TssJ |
| CG015_RS14355 (tagH) | 256778..258250 | - | 1473 | WP_094125344.1 | type VI secretion system-associated FHA domain protein TagH | ||
| T6CP014007 | TssG | CG015_RS14360 (tssG) | 258255..259277 | - | 1023 | WP_026028436.1 | type VI secretion system baseplate subunit TssG |
| T6CP014008 | TssF | CG015_RS14365 (tssF) | 259241..261010 | - | 1770 | WP_129532913.1 | type VI secretion system baseplate subunit TssF |
| CG015_RS14370 (tssE) | 261017..261454 | - | 438 | WP_013868295.1 | type VI secretion system baseplate subunit TssE | ||
| T6CP014009 | TssC | CG015_RS14375 (tssC) | 261457..262932 | - | 1476 | WP_026027753.1 | type VI secretion system contractile sheath large subunit |
| T6CP014010 | TssB | CG015_RS14380 (tssB) | 262982..263491 | - | 510 | WP_017043584.1 | type VI secretion system contractile sheath small subunit |
| CG015_RS14385 | 263880..264968 | - | 1089 | WP_129532914.1 | sel1 repeat family protein | ||
| CG015_RS14390 | 265543..267240 | + | 1698 | WP_129532915.1 | RluA family pseudouridine synthase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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