Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01252  |
| T6SS type | Type i5 |
| Strain | Vibrio parahaemolyticus strain A3 |
| Replicon (RefSeq) | chromosome (NZ_NNQJ01000119) |
| Location | 69..19440 |
| Function | anti-bacterial |
| Comment | T6SS1 can secrete VGRG and the activity was required for the observed bactericidal activity at 30°C |
| References | [1] Li P, Kinch LN, Ray A, Dalia AB, Cong Q, Nunan LM, Camilli A, Grishin NV, Salomon D, Orth K. et al (2017) Acute Hepatopancreatic Necrosis Disease-Causing Vibrio parahaemolyticus Strains Maintain an Antibacterial Type VI Secretion System with Versatile Effector Repertoires.. Appl Environ Microbiol. 83(13). [PudMed:28432099] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagF | TssA | TssB | TssC | TssE | TssF | TssG | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| T6CP015683 | TssJ | CGH00_RS20285 (tssJ) | 69..524 | + | 456 | 1693705920 | type VI secretion system lipoprotein TssJ |
| T6CP015684 | TssK | CGH00_RS20290 (tssK) | 546..1871 | + | 1326 | 516016888 | type VI secretion system baseplate subunit TssK |
| T6CP015685 | TssL | CGH00_RS20295 (tssL) | 1883..3175 | + | 1293 | 516016889 | type VI secretion system protein TssL, long form |
| T6CP015686 | TssM | CGH00_RS20300 (tssM) | 3191..6709 | + | 3519 | 1693705921 | type VI secretion system membrane subunit TssM |
| T6CP015687 | TagF | CGH00_RS20305 (tagF) | 6691..7386 | + | 696 | 1693705922 | type VI secretion system-associated protein TagF |
| CGH00_RS20310 | 7397..8185 | + | 789 | 491606245 | serine/threonine-protein phosphatase | ||
| T6CP015688 | TssA | CGH00_RS20315 (tssA) | 8182..9303 | + | 1122 | 646568760 | type VI secretion system protein TssA |
| T6CP015689 | TssB | CGH00_RS20320 (tssB) | 9319..9849 | + | 531 | 491606249 | type VI secretion system contractile sheath small subunit |
| T6CP015690 | TssC | CGH00_RS20325 (tssC) | 9849..11342 | + | 1494 | 491606251 | type VI secretion system contractile sheath large subunit |
| T6CP015691 | TssC | CGH00_RS20330 (tssC) | 11398..12909 | + | 1512 | 1879184213 | type VI secretion system contractile sheath large subunit |
| CGH00_RS20335 | 12920..13717 | + | 798 | 491606255 | protein of avirulence locus | ||
| T6CP015692 | TssE | CGH00_RS20340 (tssE) | 13726..14190 | + | 465 | 505126202 | type VI secretion system baseplate subunit TssE |
| T6CP015693 | TssF | CGH00_RS20345 (tssF) | 14187..16010 | + | 1824 | 491606259 | type VI secretion system baseplate subunit TssF |
| T6CP015694 | TssG | CGH00_RS20350 (tssG) | 16007..16972 | + | 966 | 922039643 | type VI secretion system baseplate subunit TssG |
| CGH00_RS20355 (tssH) | 16983..19440 | + | 2458 | 1693705924 | type VI secretion system ATPase TssH |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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