Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS17506  |
| T6SS type | Type i1 |
| Strain | Aliivibrio fischeri strain ES401 |
| Replicon (RefSeq) | chromosome (NZ_SRJG01000005) |
| Location | 345059..392876 |
| Function | anti-bacterial |
| Comment | Although the T6SS did not confer a competitive advantage for V. fischeri strain ES401 under planktonic conditions, a combination of both host-like pH and viscosity was necessary for T6SS competition. For ES401, high viscosity activates T6SS expression and neutral/acidic pH promotes cell-cell contact for killing, and this pH-dependent phenotype was conserved in the majority of T6SS-encoding strains examined. |
| References | [1] Speare L, Woo M, Bultman KM, Mandel MJ, Wollenberg MS, Septer AN. et al (2021) Host-Like Conditions Are Required for T6SS-Mediated Competition among Vibrio fischeri Light Organ Symbionts.. mSphere. 6(4):e0128820. [PudMed:34287008] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| VFES401_RS15675 | 340423..342714 | - | 2292 | WP_167816890.1 | patatin-like phospholipase family protein | ||
| VFES401_RS15680 | 342985..343587 | + | 603 | WP_063646018.1 | hypothetical protein | ||
| VFES401_RS15685 (tagH) | 343597..345057 | + | 1461 | WP_135354009.1 | type VI secretion system-associated FHA domain protein TagH | ||
| T6CP259573 | TssJ | VFES401_RS15690 (tssJ) | 345059..345559 | + | 501 | WP_012535132.1 | type VI secretion system lipoprotein TssJ |
| T6CP259574 | TssK | VFES401_RS15695 (tssK) | 345571..346896 | + | 1326 | WP_063658833.1 | type VI secretion system baseplate subunit TssK |
| T6CP259575 | TssL | VFES401_RS15700 (icmH) | 346893..347684 | + | 792 | WP_012534924.1 | type IVB secretion system protein IcmH/DotU |
| VFES401_RS15705 | 347725..349182 | + | 1458 | WP_135354010.1 | DUF4150 domain-containing protein | ||
| VFES401_RS15710 | 350767..351378 | + | 612 | WP_081251060.1 | glycoside hydrolase family 19 protein | ||
| VFES401_RS15715 | 351371..352171 | + | 801 | WP_063658827.1 | hypothetical protein | ||
| T6CP259576 | TssL | VFES401_RS15720 (icmH) | 352287..352976 | + | 690 | WP_081251043.1 | type IVB secretion system protein IcmH/DotU |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0371 | VFES401_RS15770 (tasR) | protein | Unknown | Aliivibrio fischeri strain ES401 | chromosome (NZ_SRJG01000005) | 373862..374311 (+) | WP_012535053.1 | hcp promotor (↓) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||