Regulators of regulatory pathway: Unknown

All displayed regulators are experimentally validated.


Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0020 experimental Qrr4 T6SS01061 experimental ncRNA Unknown Vibrio cholerae 2740-80 chromosome (NZ_CP016325) - - VCA0107 mRNA (↑)
REG0021 experimental GPY04_RS11195 (CytR) T6SS01168 experimental protein Unknown Vibrio cholerae C6706 chromosome (NZ_CP046844) 2449479..2450486 (-) 446146597 Unknown (↓)
REG0036 experimental VC1920/VCA1552_01695 (LonA) T6SS01112 experimental protein Unknown Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1845472..1847832 (-) 446970355 Unknown (↑)
REG0050 experimental PA2492 (MexT) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2807469..2808512 (+) 15597688 T6SS transcripts (↑)
REG0051 experimental PA1006 T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1090606..1090857 (+) 15596203 T6SS transcripts (↓)
REG0055 experimental PA4109 (AmpR) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4592990..4593880 (-) 15599304 T6SS transcripts (↑)
REG0058 experimental PA2976 (RNase E) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3332881..3336054 (+) 15598172 PA0077 (icmF1) expression (↑)
REG0061 experimental PA0996 (pqsA) T6SS00004 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1078462..1080015 (+) 15596193 T6SS transcripts
REG0089 experimental xac4129 (ecfK/RpoE,ECF σ factor) T6SS00028 insolico protein Unknown Xanthomonas citri pv. citri str. 306 chromosome (NC_003919) 4850278..4850805 (+) 489582896 Unknown (↓)
REG0090 experimental xac4127 (PknS) T6SS00028 insolico protein Unknown Xanthomonas citri pv. citri str. 306 chromosome (NC_003919) 4846892..4849411 (-) 505284326 Unknown (↓)
REG0106 experimental vp2049 (Thymidylate kinase, Tmk) T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0109 experimental vp1407 T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1511565..1512017 (-) 28898181 T6SS1 (VgrG1) expression and secretion (↓)
REG0131 experimental BPSL3431 (TctR) T6SS00074 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 4073388..4074029 (-) 53721038 T6SS-2 (hcp2) transcript (↑)
REG0132 experimental BPSL2246 (PpiB) T6SS00076 insolico; T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 2708622..2709113 (+) 53719855 T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓)
REG0133 experimental BPSS1504 T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006351) 2052905..2055547 (+) 499518990 hcp1 secretion
REG0186 experimental YpsIP31758_3441 (lptD) T6SS00225 experimental protein Unknown Yersinia pseudotuberculosis IP 31758 chromosome (NC_009708) 3878499..3880841 (+) 499505072 YpsIP31758_3980 (ompR) (↓)
REG0202 experimental PXO_RS20535 T6SS00287 experimental protein Unknown Xanthomonas oryzae pv. oryzae PXO99A chromosome (NC_010717) 4488457..4488843 (-) 499576999 Unknown (↓)
REG0371 experimental VFES401_RS15770 (tasR) T6SS17506 experimental protein Unknown Aliivibrio fischeri strain ES401 chromosome (NZ_SRJG01000005) 373862..374311 (+) WP_012535053.1 hcp promotor (↓)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0021 experimental GPY04_RS11195 (CytR) T6SS01168 experimental protein Unknown Vibrio cholerae C6706 chromosome (NZ_CP046844) 2449479..2450486 (-) 446146597 Unknown (↓)
REG0036 experimental VC1920/VCA1552_01695 (LonA) T6SS01112 experimental protein Unknown Vibrio cholerae strain A1552 chromosome (NZ_CP024867) 1845472..1847832 (-) 446970355 Unknown (↑)
REG0050 experimental PA2492 (MexT) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 2807469..2808512 (+) 15597688 T6SS transcripts (↑)
REG0051 experimental PA1006 T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1090606..1090857 (+) 15596203 T6SS transcripts (↓)
REG0055 experimental PA4109 (AmpR) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 4592990..4593880 (-) 15599304 T6SS transcripts (↑)
REG0058 experimental PA2976 (RNase E) T6SS00003 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 3332881..3336054 (+) 15598172 PA0077 (icmF1) expression (↑)
REG0061 experimental PA0996 (pqsA) T6SS00004 experimental protein Unknown Pseudomonas aeruginosa PAO1 chromosome (NC_002516) 1078462..1080015 (+) 15596193 T6SS transcripts
REG0089 experimental xac4129 (ecfK/RpoE,ECF σ factor) T6SS00028 insolico protein Unknown Xanthomonas citri pv. citri str. 306 chromosome (NC_003919) 4850278..4850805 (+) 489582896 Unknown (↓)
REG0090 experimental xac4127 (PknS) T6SS00028 insolico protein Unknown Xanthomonas citri pv. citri str. 306 chromosome (NC_003919) 4846892..4849411 (-) 505284326 Unknown (↓)
REG0106 experimental vp2049 (Thymidylate kinase, Tmk) T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 2150113..2150745 (-) 28898823 T6SS1 (VgrG1) expression and secretion (↓)
REG0109 experimental vp1407 T6SS00043 experimental protein Unknown Vibrio parahaemolyticus RIMD 2210633 chromosome (NC_004603) 1511565..1512017 (-) 28898181 T6SS1 (VgrG1) expression and secretion (↓)
REG0131 experimental BPSL3431 (TctR) T6SS00074 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 4073388..4074029 (-) 53721038 T6SS-2 (hcp2) transcript (↑)
REG0132 experimental BPSL2246 (PpiB) T6SS00076 insolico; T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006350) 2708622..2709113 (+) 53719855 T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓)
REG0133 experimental BPSS1504 T6SS00077 insolico protein Unknown Burkholderia pseudomallei K96243 chromosome (NC_006351) 2052905..2055547 (+) 499518990 hcp1 secretion
REG0186 experimental YpsIP31758_3441 (lptD) T6SS00225 experimental protein Unknown Yersinia pseudotuberculosis IP 31758 chromosome (NC_009708) 3878499..3880841 (+) 499505072 YpsIP31758_3980 (ompR) (↓)
REG0202 experimental PXO_RS20535 T6SS00287 experimental protein Unknown Xanthomonas oryzae pv. oryzae PXO99A chromosome (NC_010717) 4488457..4488843 (-) 499576999 Unknown (↓)
REG0371 experimental VFES401_RS15770 (tasR) T6SS17506 experimental protein Unknown Aliivibrio fischeri strain ES401 chromosome (NZ_SRJG01000005) 373862..374311 (+) WP_012535053.1 hcp promotor (↓)

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Regulator ID Locus tag (Gene) Related T6SS Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)
REG0020 experimental Qrr4 T6SS01061 experimental ncRNA Unknown Vibrio cholerae 2740-80 chromosome (NZ_CP016325) - - VCA0107 mRNA (↑)