Detailed information of regulator
Summary
| Regulator ID | REG0051  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | Unknown |
| KEGG pathway (determined by BlastKOALA) | Sulfur relay system (map04122) |
| Related T6SS | T6SS00003 (Type i3) |
| Strain | Pseudomonas aeruginosa PAO1 |
| Replicon | chromosome |
| Sequence | Protein sequence (84 a.a.); Nucleotide sequence (252 bp) |
| Description | The ΔPA1006 mutant displayed reduced expression of several Type-VI Secretion System components (PA0074-75, PA0077-78, PA0085, PA0090, PA0262, and PA3294) by microarray analysis |
| Reference |
External database links
| Locus tag (Gene) | PA1006 |
| Coordinates (Strand) | 1090606..1090857 (+) |
| NCBI ID | 15596203 |
| RefSeq | NC_002516 |
| Uniprot ID | Q9I4W7_PSEAE |
| KEGG ID | pae:PA1006 |
| KEGG pathway (determined by BlastKOALA) | map04122 |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| T6SS transcripts | ↓ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| TusA | PF01206.19 | 3.1e-21 | 14..82 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-83 | MTDNDSSPLVCDAELDASGLNCPLPLLKAKLELNRLPSGGVLKVIATDAGSQRDFRAFAQLAGHELLREEAAEGVYRYWLRKR |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9942 | - | - |
Protein sequence of regulator: 84 a.a. .
>REG0051 NC_002516:1090606-1090857 [Pseudomonas aeruginosa PAO1]
MTDNDSSPLVCDAELDASGLNCPLPLLKAKLELNRLPSGGVLKVIATDAGSQRDFRAFAQLAGHELLREEAAEGVYRYWL
RKR*
MTDNDSSPLVCDAELDASGLNCPLPLLKAKLELNRLPSGGVLKVIATDAGSQRDFRAFAQLAGHELLREEAAEGVYRYWL
RKR*
Nucleotide sequence of regulator: 252 bp .
>REG0051 NC_002516:1090606-1090857 [Pseudomonas aeruginosa PAO1]
ATGACGGATAACGATTCATCCCCCCTGGTATGTGACGCGGAGCTGGATGCCAGTGGTCTCAATTGTCCGCTGCCCCTGCT
AAAGGCCAAGCTGGAGCTGAACCGCCTGCCCAGCGGCGGGGTGCTCAAGGTGATCGCCACCGATGCCGGGTCGCAGCGAG
ACTTCCGGGCCTTCGCCCAGCTCGCCGGCCATGAACTGCTGCGCGAAGAGGCCGCCGAAGGCGTCTATCGATACTGGCTG
CGCAAGCGTTAG
ATGACGGATAACGATTCATCCCCCCTGGTATGTGACGCGGAGCTGGATGCCAGTGGTCTCAATTGTCCGCTGCCCCTGCT
AAAGGCCAAGCTGGAGCTGAACCGCCTGCCCAGCGGCGGGGTGCTCAAGGTGATCGCCACCGATGCCGGGTCGCAGCGAG
ACTTCCGGGCCTTCGCCCAGCTCGCCGGCCATGAACTGCTGCGCGAAGAGGCCGCCGAAGGCGTCTATCGATACTGGCTG
CGCAAGCGTTAG