Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00076  |
| T6SS type | Type i3 |
| Strain | Burkholderia pseudomallei K96243 |
| Replicon (RefSeq) | chromosome II (NC_006351) |
| Location | 2831227..2856994 |
| Function | - |
| Comment | - |
| References | [1] Burtnick MN et al (2011) The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 79(4):1512-25. [PudMed:21300775] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BPS_RS32170 | 2826777..2827034 | + | 258 | WP_004548749.1 | transposase | ||
| BPS_RS30210 | 2827811..2828551 | + | 741 | WP_004524822.1 | hypothetical protein | ||
| BPS_RS30215 | 2828980..2829328 | + | 349 | pseudogene | recombinase family protein | ||
| BPS_RS30220 | 2829283..2829711 | - | 429 | WP_009941143.1 | DUF746 domain-containing protein | ||
| BPS_RS30225 | 2829708..2830541 | - | 834 | WP_045606131.1 | RHS repeat protein | ||
| BPS_RS30230 | 2830501..2831211 | - | 711 | WP_004539259.1 | hypothetical protein | ||
| T6CP000673 | TssI | BPS_RS30235 (tssI) | 2831227..2833431 | - | 2205 | WP_004203275.1 | type VI secretion system tip protein VgrG |
| T6CP000674 | TssH | BPS_RS30240 (tssH) | 2833428..2836094 | - | 2667 | WP_004529320.1 | type VI secretion system ATPase TssH |
| T6CP000675 | TssG | BPS_RS30245 (tssG) | 2836073..2837551 | - | 1479 | WP_004540225.1 | type VI secretion system baseplate subunit TssG |
| T6CP000676 | TssF | BPS_RS30250 (tssF) | 2837548..2839419 | - | 1872 | WP_004524812.1 | type VI secretion system baseplate subunit TssF |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0132 | BPSL2246 (PpiB) | protein | Unknown | Burkholderia pseudomallei K96243 | chromosome (NC_006350) | 2708622..2709113 (+) | 53719855 | T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||