Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00077 insolico
T6SS type Type i4b
Strain Burkholderia pseudomallei K96243
Replicon (RefSeq) chromosome I (NC_006350)
Location 3697190..3717176
Function -
Comment -
References
[1] Burtnick MN et al (2011) The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 79(4):1512-25. [PudMed:21300775]
insolico Bioinformatics investigation has been performed.

T6SS components and genome coordinates

ComponentTagLTssATssBTssCTssDTssETssFTssGTssHTssJTssKTssLTssM
Number1111111111111


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Component ID
Component
Locus tag (Gene)
Coordinate
Strand
Size (bp)
NCBI ID
Product
BPS_RS166703693290..3694738+1449WP_009938786.1TolC family type I secretion outer membrane protein
BPS_RS166753694948..3695934-987WP_004555447.1hypothetical protein
BPS_RS166803696060..3696911+852WP_004199998.1M15 family metallopeptidase
T6CP000613TssMBPS_RS16690 (tssM)3697190..3701083+3894WP_004555848.1type VI secretion system membrane subunit TssM
BPS_RS16695 (tagF)3701080..3702069+990WP_004200003.1type VI secretion system-associated protein TagF
T6CP011469TagLBPS_RS167003702074..3703006+933WP_011205261.1OmpA family protein
T6CP000614TssABPS_RS16705 (tssA)3703205..3704326-1122WP_004549922.1type VI secretion system protein TssA
T6CP000615TssHBPS_RS16710 (tssH)3704416..3707085-2670WP_004549921.1type VI secretion system ATPase TssH
T6CP000616TssGBPS_RS16715 (tssG)3707119..3708219-1101WP_004200010.1type VI secretion system baseplate subunit TssG
T6CP000617TssFBPS_RS16720 (tssF)3708183..3710021-1839WP_004527836.1type VI secretion system baseplate subunit TssF
Showing 1 to 10 of 23 rows rows per page
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
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Regulator ID
Locus tag (Gene)
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
REG0132 experimentalBPSL2246 (PpiB)proteinUnknownBurkholderia pseudomallei K96243chromosome (NC_006350)2708622..2709113 (+)53719855T6SS-3 (BPSS2099/TssCIII and BPSS2098/HcpIII) expression (↑); T6SS-6 (hcp6) transcript (↓)
REG0133 experimentalBPSS1504proteinUnknownBurkholderia pseudomallei K96243chromosome (NC_006351)2052905..2055547 (+)499518990hcp1 secretion
REG0134 experimentalBPSS1546 (BsaN)proteinBsaN regulonBurkholderia pseudomallei K96243chromosome (NC_006351)2100565..2101230 (-)490660320BPSS1495 (virA) promotor (↓)
REG0135 experimentalBPS_RS27070 (bicA)proteinBsaN regulonBurkholderia pseudomallei K96243chromosome (NC_006351)2087441..2087956 (-)490293043BPSS 1495(virA) (↓)
REG0136 experimentalBPS_RS27175 (bprP)proteinBsaN regulonBurkholderia pseudomallei K96243chromosome (NC_006351)2105881..2106081 (+)490293055BPSS1546 (BsaN) (↓)
REG0137 experimentalBPSS1495 (virA)proteinTCS-RR; BsaN regulonBurkholderia pseudomallei K96243chromosome (NC_006351)2038711..2040555 (-)499518988T6SS-1 transpript (↓)
REG0138 experimentalBPSS1494 (virG)proteinTCS-HK; BsaN regulonBurkholderia pseudomallei K96243chromosome (NC_006351)2037977..2038714 (-)490663798BPSS1495 (virA) (↓)
REG0139 experimentalBPSL1105 (bprP)proteinbspR-dependent signalling cascadeBurkholderia pseudomallei K96243chromosome (NC_006350)1275668..1276300 (+)490290369tssA expression (↓)
REG0144 experimentalBPSS1520 (bprC)proteinbspR-dependent signalling cascadeBurkholderia pseudomallei K96243chromosome (NC_006351)2072125..2073186 (-)499518995tssA expression (↓)
REG0145 experimentalBPSS1495 (virA)proteinTCS-HKBurkholderia pseudomallei K96243chromosome (NC_006351)2038711..2040555 (-)53722517hcp1 expression (↓)
Showing 1 to 10 of 11 rows rows per page

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
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Effector ID
Locus tag (Gene)
Classification
Cognate immunity protein
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
No matching records found

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
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Immunity protein ID
Locus tag (Gene)
Cognate effector
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
No matching records found

experimental Experimental investigation has been performed.
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Accessory protein ID
Locus tag (Gene)
Type            
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Related structure protein
Related effector
No matching records found