Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00077  |
| T6SS type | Type i4b |
| Strain | Burkholderia pseudomallei K96243 |
| Replicon (RefSeq) | chromosome I (NC_006350) |
| Location | 3697190..3717176 |
| Function | - |
| Comment | - |
| References | [1] Burtnick MN et al (2011) The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 79(4):1512-25. [PudMed:21300775] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TagL | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BPS_RS16670 | 3693290..3694738 | + | 1449 | WP_009938786.1 | TolC family type I secretion outer membrane protein | ||
| BPS_RS16675 | 3694948..3695934 | - | 987 | WP_004555447.1 | hypothetical protein | ||
| BPS_RS16680 | 3696060..3696911 | + | 852 | WP_004199998.1 | M15 family metallopeptidase | ||
| T6CP000613 | TssM | BPS_RS16690 (tssM) | 3697190..3701083 | + | 3894 | WP_004555848.1 | type VI secretion system membrane subunit TssM |
| BPS_RS16695 (tagF) | 3701080..3702069 | + | 990 | WP_004200003.1 | type VI secretion system-associated protein TagF | ||
| T6CP011469 | TagL | BPS_RS16700 | 3702074..3703006 | + | 933 | WP_011205261.1 | OmpA family protein |
| T6CP000614 | TssA | BPS_RS16705 (tssA) | 3703205..3704326 | - | 1122 | WP_004549922.1 | type VI secretion system protein TssA |
| T6CP000615 | TssH | BPS_RS16710 (tssH) | 3704416..3707085 | - | 2670 | WP_004549921.1 | type VI secretion system ATPase TssH |
| T6CP000616 | TssG | BPS_RS16715 (tssG) | 3707119..3708219 | - | 1101 | WP_004200010.1 | type VI secretion system baseplate subunit TssG |
| T6CP000617 | TssF | BPS_RS16720 (tssF) | 3708183..3710021 | - | 1839 | WP_004527836.1 | type VI secretion system baseplate subunit TssF |
| T6CP000618 | TssE | BPS_RS16725 (tssE) | 3710101..3710583 | - | 483 | WP_004204912.1 | type VI secretion system baseplate subunit TssE |
| T6CP000619 | TssD | BPS_RS16730 | 3710641..3711144 | - | 504 | WP_004527837.1 | type VI secretion system tube protein Hcp |
| T6CP000620 | TssC | BPS_RS16735 (tssC) | 3711217..3712707 | - | 1491 | WP_004521953.1 | type VI secretion system contractile sheath large subunit |
| T6CP000621 | TssB | BPS_RS16740 (tssB) | 3712724..3713242 | - | 519 | WP_004521952.1 | type VI secretion system contractile sheath small subunit |
| BPS_RS16745 | 3713279..3713950 | - | 672 | WP_004531875.1 | tetratricopeptide repeat protein | ||
| T6CP000622 | TssJ | BPS_RS16750 (tssJ) | 3714325..3714939 | + | 615 | WP_004521950.1 | type VI secretion system lipoprotein TssJ |
| T6CP000623 | TssK | BPS_RS16755 (tssK) | 3715048..3716394 | + | 1347 | WP_004521949.1 | type VI secretion system baseplate subunit TssK |
| T6CP000624 | TssL | BPS_RS16760 | 3716391..3717176 | + | 786 | WP_004521948.1 | type IVB secretion system protein IcmH/DotU |
| BPS_RS16765 | 3717661..3717999 | - | 339 | WP_004535002.1 | Arm DNA-binding domain-containing protein | ||
| BPS_RS16770 | 3718434..3719234 | + | 801 | WP_009932052.1 | hypothetical protein | ||
| BPS_RS16775 | 3719241..3720311 | + | 1071 | WP_004535005.1 | ImmA/IrrE family metallo-endopeptidase | ||
| BPS_RS16780 | 3720594..3721714 | + | 1121 | WP_038802333.1 | IS3 family transposase | ||
| BPS_RS16785 | 3721847..3722107 | + | 261 | WP_076802946.1 | tyrosine-type recombinase/integrase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed. Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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