Regulators of regulatory pathway: TCS-HK

All displayed regulators are experimentally validated.


Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
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Regulator ID
Locus tag (Gene)
Related T6SS
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
REG0003 experimentalRT90_01105 (rcsC)T6SS01264 experimentalproteinTCS-HKSerratia marcescens strain RM66262chromosome (JWLO01000001)232638..235499 (+)735006326RT90_01115 (rcsB) (↑)
REG0045 experimentalPA0610 (prtN)T6SS00003 experimentalproteinTCS-HKPseudomonas aeruginosa PAO1chromosome (NC_002516)672777..673091 (-)15595807PA0611 (prtR) (↑)
REG0084 experimentalchvGT6SS00016 experimentalproteinTCS-HKAgrobacterium fabrum str. C58chromosome (NC_003062)34679..36469 (-)chvI (↓)
REG0100 experimentalVP_RS12495 (barA)T6SS00043 experimental; T6SS00044 experimentalproteinTCS-HKVibrio parahaemolyticus RIMD 2210633chromosome (NC_004603)2712492..2715290 (+)491625032Hcp expression and secretion (↓)
REG0128 experimentalBMAA0745 (VirA)T6SS00070 experimentalproteinTCS-HKBurkholderia mallei ATCC 23344chromosome (NC_006349)762932..764776 (+)490305845Hcp1 (BMAA0742) expression (↓)
REG0130 experimentalBMAA0745 (VirA)T6SS00070 experimentalproteinTCS-HKBurkholderia mallei ATCC 23344chromosome (NC_006349)763148..764776 (+)53717365BMAA0746 (VirG) (↓)
REG0138 experimentalBPSS1494 (virG)T6SS00077 insolicoproteinTCS-HK; BsaN regulonBurkholderia pseudomallei K96243chromosome (NC_006351)2037977..2038714 (-)490663798BPSS1495 (virA) (↓)
REG0145 experimentalBPSS1495 (virA)T6SS00077 insolicoproteinTCS-HKBurkholderia pseudomallei K96243chromosome (NC_006351)2038711..2040555 (-)53722517hcp1 expression (↓)
REG0150 experimentalPsyr_3698 (gacS)T6SS00086 experimentalproteinTCS-HKPseudomonas syringae pv. syringae B728achromosome (NC_007005)4385550..4388303 (+)499587812T6SS transcription (↓)
REG0175 experimentalFTN_RS08805 (KdpD)T6SS00158 experimentalproteinTCS-HKFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1838601..1841282 (-)489131611FTN_1465 (pmrA) (↓)
Showing 1 to 10 of 16 rows rows per page

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Loading, please wait
Regulator ID
Locus tag (Gene)
Related T6SS
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
REG0003 experimentalRT90_01105 (rcsC)T6SS01264 experimentalproteinTCS-HKSerratia marcescens strain RM66262chromosome (JWLO01000001)232638..235499 (+)735006326RT90_01115 (rcsB) (↑)
REG0045 experimentalPA0610 (prtN)T6SS00003 experimentalproteinTCS-HKPseudomonas aeruginosa PAO1chromosome (NC_002516)672777..673091 (-)15595807PA0611 (prtR) (↑)
REG0084 experimentalchvGT6SS00016 experimentalproteinTCS-HKAgrobacterium fabrum str. C58chromosome (NC_003062)34679..36469 (-)chvI (↓)
REG0100 experimentalVP_RS12495 (barA)T6SS00043 experimental; T6SS00044 experimentalproteinTCS-HKVibrio parahaemolyticus RIMD 2210633chromosome (NC_004603)2712492..2715290 (+)491625032Hcp expression and secretion (↓)
REG0128 experimentalBMAA0745 (VirA)T6SS00070 experimentalproteinTCS-HKBurkholderia mallei ATCC 23344chromosome (NC_006349)762932..764776 (+)490305845Hcp1 (BMAA0742) expression (↓)
REG0130 experimentalBMAA0745 (VirA)T6SS00070 experimentalproteinTCS-HKBurkholderia mallei ATCC 23344chromosome (NC_006349)763148..764776 (+)53717365BMAA0746 (VirG) (↓)
REG0138 experimentalBPSS1494 (virG)T6SS00077 insolicoproteinTCS-HK; BsaN regulonBurkholderia pseudomallei K96243chromosome (NC_006351)2037977..2038714 (-)490663798BPSS1495 (virA) (↓)
REG0145 experimentalBPSS1495 (virA)T6SS00077 insolicoproteinTCS-HKBurkholderia pseudomallei K96243chromosome (NC_006351)2038711..2040555 (-)53722517hcp1 expression (↓)
REG0150 experimentalPsyr_3698 (gacS)T6SS00086 experimentalproteinTCS-HKPseudomonas syringae pv. syringae B728achromosome (NC_007005)4385550..4388303 (+)499587812T6SS transcription (↓)
REG0175 experimentalFTN_RS08805 (KdpD)T6SS00158 experimentalproteinTCS-HKFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1838601..1841282 (-)489131611FTN_1465 (pmrA) (↓)
Showing 1 to 10 of 16 rows rows per page

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
Loading, please wait
Regulator ID
Locus tag (Gene)
Related T6SS
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
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