SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP000614
Component protein type	TssA
T6SS ID (Type)	T6SS00077 (Type i4b)
Strain	Burkholderia pseudomallei K96243
Replicon	chromosome I
Sequence	Protein sequence (374 a.a.); Nucleotide sequence (1122 bp)
Reference	[1] Burtnick MN, Brett PJ, Harding SV, et al. The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 2011 Apr;79(4):1512-25. doi: 10.1128/IAI.01218-10. Epub 2011 Feb 7. PMID: 21300775

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	BPS_RS16705
Coordinate (Strand)	3703205..3704326 (-)
NCBI ID	WP_004549922.1
RefSeq	NC_006350
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

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Domain	Pfam ID	E-value	Aligned region
ImpA_N	PF06812.14	6.1e-37	9..131

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Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

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Prediction	Region	Sequence
No matching records found

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

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Prediction	Probability	Cleavage site	Signal peptide sequence
		-	-

Protein sequence: 374 a.a.

						>T6CP000614 NC_006350:c3704326-3703205 [Burkholderia pseudomallei K96243] [TssA]
MPTNLTELLTPISEASPCGDDLLFSAEFDAIQHARKFDDPSLDQGEWITDIKEADWGFVVEQASALLRERTKDLRLAVWL
TEALAIEDGIGGLTQGYTLLTSLCRQFWDHVHPLPDGDDAEYRLGNVAWLAGRTVDLLRAVPLTDGAANAFSELDWDVAQ
HVAQAIRRDPEQASEIARGKPSVEQIEASKRMTPVAFYARLLGELKAFQAALDALEQELDGRAGDAAPSFRQARDAYETV
YRLAERFAKEQGYSADAQPQAVAPPAPSERAEPSFKTPLHSEEPVPRHAHAPSAPAPIVIAGIQNRAQAVEQLRAVAKYF
RGTEPHSPVAYLADKAAEWADMPLHQWLASVVKDDGSLAHIRELLGLKPDDNA*					

Nucleotide sequence: 1122 bp

						>T6CP000614 NC_006350:c3704326-3703205 [Burkholderia pseudomallei K96243] [TssA]
ATGCCGACCAACCTCACCGAGCTGCTGACGCCGATCAGCGAAGCGTCGCCGTGCGGCGACGATCTCCTGTTCTCCGCCGA
ATTCGACGCGATCCAGCACGCGCGCAAGTTCGACGATCCGTCGCTCGACCAGGGCGAATGGATCACCGATATCAAGGAAG
CGGACTGGGGCTTCGTCGTCGAGCAAGCGAGCGCGCTGTTGCGCGAGCGCACGAAGGATCTGCGGCTCGCGGTATGGCTG
ACCGAGGCGCTCGCGATCGAGGACGGCATCGGTGGGCTCACGCAGGGCTACACGCTGCTCACGAGCCTCTGCCGGCAGTT
CTGGGACCACGTGCATCCGCTGCCCGACGGCGACGACGCCGAATACCGGCTCGGCAACGTCGCGTGGCTCGCCGGGCGCA
CGGTCGATCTGCTGCGCGCGGTGCCGCTCACCGACGGCGCGGCGAATGCGTTCAGCGAGCTCGACTGGGACGTCGCGCAA
CACGTCGCGCAGGCGATCCGGCGCGATCCCGAACAGGCGAGCGAGATCGCGCGCGGCAAGCCGTCCGTCGAGCAGATCGA
GGCGTCGAAGCGGATGACGCCCGTGGCGTTCTACGCGCGGCTGCTCGGCGAGCTGAAAGCGTTCCAGGCGGCGCTCGACG
CGCTCGAGCAGGAACTCGACGGGCGGGCGGGCGACGCGGCGCCGAGCTTCCGGCAGGCGCGCGACGCGTACGAAACCGTC
TACCGGCTCGCCGAACGCTTCGCGAAGGAGCAGGGCTACTCGGCCGACGCGCAGCCGCAGGCCGTCGCGCCGCCCGCGCC
GAGCGAGCGCGCGGAGCCGAGCTTCAAGACGCCGCTTCATTCGGAGGAACCCGTGCCGAGACACGCACACGCGCCGTCCG
CGCCCGCGCCGATCGTGATCGCCGGCATTCAGAATCGCGCGCAGGCCGTCGAGCAACTGCGCGCGGTCGCGAAATATTTC
CGCGGAACCGAGCCGCACAGCCCCGTCGCGTATCTCGCCGACAAGGCGGCCGAATGGGCGGACATGCCGCTGCATCAATG
GCTTGCGTCGGTCGTCAAGGACGACGGCTCGCTCGCGCATATCCGCGAGCTGCTCGGCCTGAAGCCGGACGATAACGCGT
GA					