Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01061  |
| T6SS type | Type i1 |
| Strain | Vibrio cholerae 2740-80 |
| Replicon (RefSeq) | chromosome (NZ_CP016325) |
| Location | 116326..135495 |
| Function | - |
| Comment | - |
| References | [1] Szwedziak P, Pilhofer M. et al (2019) Bidirectional contraction of a type six secretion system.. Nat Commun. 10(1):1565. [PudMed:30952865] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BBB50_RS14405 | 112171..113850 | - | 1680 | WP_001275247.1 | RluA family pseudouridine synthase | ||
| BBB50_RS14410 | 114622..114906 | + | 285 | WP_000526403.1 | type VI secretion system PAAR protein | ||
| BBB50_RS14415 | 114974..115894 | + | 921 | WP_001901866.1 | sel1 repeat family protein | ||
| T6CP013707 | TssB | BBB50_RS14420 (tssB) | 116326..116832 | + | 507 | WP_000031391.1 | type VI secretion system contractile sheath small subunit |
| T6CP013708 | TssC | BBB50_RS14425 (tssC) | 116876..118351 | + | 1476 | WP_000108140.1 | type VI secretion system contractile sheath large subunit |
| T6CP013709 | TssE | BBB50_RS14430 (tssE) | 118354..118791 | + | 438 | WP_000221000.1 | type VI secretion system baseplate subunit TssE |
| T6CP013710 | TssF | BBB50_RS14435 (tssF) | 118797..120566 | + | 1770 | WP_000189792.1 | type VI secretion system baseplate subunit TssF |
| T6CP013711 | TssG | BBB50_RS14440 (tssG) | 120530..121546 | + | 1017 | WP_000510181.1 | type VI secretion system baseplate subunit TssG |
| BBB50_RS14445 (tagH) | 121549..123036 | + | 1488 | WP_001089704.1 | type VI secretion system-associated FHA domain protein TagH | ||
| T6CP013712 | TssJ | BBB50_RS14450 (tssJ) | 123039..123515 | + | 477 | WP_001045311.1 | type VI secretion system lipoprotein TssJ |
| T6CP013713 | TssK | BBB50_RS14455 (tssK) | 123522..124856 | + | 1335 | WP_000458007.1 | type VI secretion system baseplate subunit TssK |
| T6CP013714 | TssL | BBB50_RS14460 | 124859..125632 | + | 774 | WP_000083409.1 | type IVB secretion system protein IcmH/DotU |
| T6CP013715 | TssH | BBB50_RS14465 (tssH) | 125658..128267 | + | 2610 | WP_000619136.1 | type VI secretion system ATPase TssH |
| BBB50_RS14470 (vasH) | 128270..129862 | + | 1593 | WP_000084793.1 | sigma-54 dependent T6SS transcriptional regulator VasH | ||
| BBB50_RS14475 (tagO) | 129859..130515 | + | 657 | WP_001223388.1 | type VI secretion system-associated protein TagO | ||
| T6CP013716 | TssA | BBB50_RS14480 (vasJ) | 130525..131934 | + | 1410 | WP_000426093.1 | TssA family type VI secretion system protein VasJ |
| T6CP013717 | TssM | BBB50_RS14485 (tssM) | 131995..135495 | + | 3501 | WP_000225015.1 | type VI secretion system membrane subunit TssM |
| BBB50_RS14490 | 135546..136808 | + | 1263 | WP_000073077.1 | ImpA family type VI secretion system protein | ||
| BBB50_RS14500 (tssI) | 137061..140114 | + | 3054 | WP_000113295.1 | type VI secretion system tip protein VgrG | ||
| BBB50_RS14505 | 140111..140479 | + | 369 | WP_001061295.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0020 |
Qrr4 | ncRNA | Unknown | Vibrio cholerae 2740-80 | chromosome (NZ_CP016325) | - | - | VCA0107 mRNA (↑) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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