Detailed information of component protein


Summary

Component ID T6CP013716
Component protein type TssA
T6SS ID (Type) T6SS01061 experimental (Type i1)
Strain Vibrio cholerae 2740-80
Replicon chromosome
Sequence Protein sequence (470 a.a.); Nucleotide sequence (1410 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) BBB50_RS14480
Coordinate (Strand) 130525..131934 (+)
NCBI ID WP_000426093.1
RefSeq NZ_CP016325
Uniprot ID Q9KN46_VIBCH, A0A0X1L1Y9_VIBCO, A0A0H3AGW2_VIBC3, A0A0K9UXP5_VIBCL, A0A7U8WPS9_VIBCL, A0A0H3Q279_VIBCL, C3LUE3_VIBCM, A0A023PTI1_VIBCL
KEGG ID vcq:EN18_04320, vch:VCA0119, vcm:VCM66_A0117, vco:VC0395_0018
PDB ID 6RIU
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_VasJ PF16989.7 1.8e-74 216..464
ImpA_N PF06812.14 9.6e-25 12..125
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-469 MEMTEYRQCVAKPISSSNPVGERLVDHPLFDFIEDQMMKVGSLSHASVQWDEVEHSTLKLLGEQSKDIKLLVYLLQCLHNQVTPTRLITSFAVMSEFLNQYWNDSYPAPGPRGNLPRRKFFSQMAQRFTTVIEKFDFHHLDEADRQALQAAVEEWQQAVEKQGLSSELVESVVVRITAEIKRAEQRQQVTAQSSAERETPSAATPSPAASMVVDHSSDKAAKQTLLKVADFLAEQEFGIALSIRLRRFAVWGSITSLPDHKPDGETLLRGMQADRVKDYQDQLRHPDLALWRKVEQSLTMAPYWFEGQWMSYTIAQQLGKSDWCQAIAEETQQFLRRLPSLLELKFKGGEPFVSDSVKEWLASVGQSQGAAGQSVGGDWQEKRKEAFQLAKEGGIAVALSMLNDGLVSAVEPRDKFYWRLLSADLLRANHLDAMAGEQYQTLLNQVTTLSVPEWEPSLVEQIQRYTTSE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9958 - -


  Protein sequence: 470 a.a.    

>T6CP013716 NZ_CP016325:130525-131934 [Vibrio cholerae 2740-80] [TssA]
MEMTEYRQCVAKPISSSNPVGERLVDHPLFDFIEDQMMKVGSLSHASVQWDEVEHSTLKLLGEQSKDIKLLVYLLQCLHN
QVTPTRLITSFAVMSEFLNQYWNDSYPAPGPRGNLPRRKFFSQMAQRFTTVIEKFDFHHLDEADRQALQAAVEEWQQAVE
KQGLSSELVESVVVRITAEIKRAEQRQQVTAQSSAERETPSAATPSPAASMVVDHSSDKAAKQTLLKVADFLAEQEFGIA
LSIRLRRFAVWGSITSLPDHKPDGETLLRGMQADRVKDYQDQLRHPDLALWRKVEQSLTMAPYWFEGQWMSYTIAQQLGK
SDWCQAIAEETQQFLRRLPSLLELKFKGGEPFVSDSVKEWLASVGQSQGAAGQSVGGDWQEKRKEAFQLAKEGGIAVALS
MLNDGLVSAVEPRDKFYWRLLSADLLRANHLDAMAGEQYQTLLNQVTTLSVPEWEPSLVEQIQRYTTSE*

  Nucleotide sequence: 1410 bp    

>T6CP013716 NZ_CP016325:130525-131934 [Vibrio cholerae 2740-80] [TssA]
ATGGAAATGACTGAATACCGTCAGTGTGTGGCCAAACCGATCAGCAGTAGCAATCCTGTCGGAGAGCGGCTAGTCGATCA
CCCACTGTTTGATTTTATTGAGGATCAGATGATGAAAGTGGGCTCTCTCTCTCACGCTTCAGTGCAGTGGGATGAAGTGG
AGCACAGCACTCTCAAACTGCTTGGTGAACAGAGTAAAGACATCAAGCTTTTGGTTTACCTGCTGCAGTGTCTGCATAAC
CAAGTTACCCCGACGCGCCTTATTACCTCGTTTGCGGTGATGAGTGAGTTCCTCAATCAATATTGGAACGACAGTTATCC
AGCGCCGGGCCCACGTGGCAATCTGCCGCGACGTAAATTTTTCAGCCAGATGGCGCAACGTTTTACCACGGTGATCGAAA
AGTTCGATTTTCATCATCTGGATGAAGCGGATCGCCAAGCGCTACAAGCGGCGGTTGAAGAGTGGCAACAAGCCGTTGAG
AAACAAGGGCTCTCTTCTGAGTTGGTGGAGTCTGTGGTGGTGCGAATTACCGCGGAGATCAAACGCGCAGAGCAGCGCCA
GCAAGTGACGGCGCAAAGCAGCGCGGAGCGTGAAACACCAAGTGCTGCAACGCCTTCTCCTGCGGCGAGTATGGTGGTGG
ATCATTCGAGTGACAAAGCAGCGAAACAAACCCTACTCAAAGTGGCAGATTTTCTTGCCGAACAAGAGTTTGGTATCGCT
CTTTCGATTCGTCTGCGCCGCTTTGCGGTGTGGGGCAGCATTACCTCATTGCCCGATCATAAACCCGATGGTGAAACACT
GCTGCGTGGAATGCAGGCGGATCGCGTCAAGGATTACCAAGATCAACTTCGTCACCCCGATTTAGCCTTGTGGCGCAAAG
TCGAACAGAGCTTAACCATGGCTCCTTATTGGTTTGAAGGACAGTGGATGAGTTACACCATTGCCCAGCAACTCGGCAAA
AGTGATTGGTGTCAGGCGATTGCCGAAGAAACACAACAGTTTTTACGTCGTTTGCCTTCGCTGCTTGAGCTCAAATTCAA
AGGCGGAGAGCCGTTTGTCAGCGATTCGGTCAAAGAGTGGCTGGCGAGCGTAGGTCAGAGCCAAGGTGCTGCGGGGCAAT
CGGTCGGCGGAGATTGGCAAGAGAAGCGTAAAGAGGCGTTTCAACTGGCTAAAGAAGGTGGAATCGCGGTGGCACTTTCC
ATGCTCAATGATGGCTTGGTCAGTGCGGTGGAGCCGCGAGACAAATTTTACTGGCGATTGCTATCGGCAGATCTGCTGCG
GGCAAATCATCTCGATGCGATGGCTGGTGAACAGTATCAAACTCTGCTCAATCAGGTAACGACGCTGTCTGTTCCTGAGT
GGGAACCGAGTTTAGTGGAACAAATTCAAAGATATACAACGTCAGAGTAA