Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00074  |
| T6SS type | Type i3 |
| Strain | Burkholderia pseudomallei K96243 |
| Replicon (RefSeq) | chromosome II (NC_006351) |
| Location | 702116..728854 |
| Function | - |
| Comment | - |
| References | [1] Burtnick MN et al (2011) The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 79(4):1512-25. [PudMed:21300775] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BPS_RS21480 | 697828..698517 | - | 690 | WP_004188272.1 | CDP-alcohol phosphatidyltransferase family protein | ||
| BPS_RS21485 | 698882..700396 | + | 1515 | WP_004188420.1 | acetyl-CoA hydrolase/transferase family protein | ||
| T6CP000651 | TssA | BPS_RS21490 | 702116..703054 | + | 939 | WP_004525545.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP000652 | TssB | BPS_RS21495 (tssB) | 703088..703636 | + | 549 | WP_004202234.1 | type VI secretion system contractile sheath small subunit |
| T6CP000653 | TssC | BPS_RS21500 (tssC) | 703639..705144 | + | 1506 | WP_004190846.1 | type VI secretion system contractile sheath large subunit |
| T6CP000654 | TssD | BPS_RS21505 | 705288..705815 | + | 528 | WP_004530039.1 | type VI secretion system tube protein Hcp |
| T6CP000655 | TssE | BPS_RS21510 | 705895..706326 | + | 432 | WP_004190879.1 | GPW/gp25 family protein |
| T6CP000656 | TssF | BPS_RS21515 (tssF) | 706340..708202 | + | 1863 | WP_004196180.1 | type VI secretion system baseplate subunit TssF |
| T6CP000657 | TssG | BPS_RS21520 (tssG) | 708199..709188 | + | 990 | WP_004190851.1 | type VI secretion system baseplate subunit TssG |
| T6CP000658 | TssH | BPS_RS21525 (tssH) | 709191..712061 | + | 2871 | WP_004525547.1 | type VI secretion system ATPase TssH |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0131 | BPSL3431 (TctR) | protein | Unknown | Burkholderia pseudomallei K96243 | chromosome (NC_006350) | 4073388..4074029 (-) | 53721038 | T6SS-2 (hcp2) transcript (↑) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||