SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP000651
Component protein type	TssA
T6SS ID (Type)	T6SS00074 (Type i3)
Strain	Burkholderia pseudomallei K96243
Replicon	chromosome II
Sequence	Protein sequence (313 a.a.); Nucleotide sequence (939 bp)
Reference	[1] Burtnick MN, Brett PJ, Harding SV, et al. The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 2011 Apr;79(4):1512-25. doi: 10.1128/IAI.01218-10. Epub 2011 Feb 7. PMID: 21300775

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	BPS_RS21490
Coordinate (Strand)	702116..703054 (+)
NCBI ID	WP_004525545.1
RefSeq	NC_006351
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
ImpA_N	PF06812.14	3.1e-14	14..108

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-312	MNNDALPGHSPDLLDFDEDFIKIDAAICEYDSVGYAPQRKGESAFQWASIETGCLALLKKAKDVRVGIWHLRACIARRGLSGLADGVRSLADLMSAPVEELHPRALPDESPGETLLIHLGWLAGPQFLHQLGSSRFEDRDATLNDLIGGRAAAIVEDRDYRLRANTLVHDIQDSLSRIRESIAAAEQELNVSRALDLLSVAASRLTQAQAGGADGASVESDAPVDAPAGASAPGAQQPMAGPGGVLRSRQEVGAALDRIVEYFRVHEPSHPAPIFLSRIQRMLGAGFEEVMAELYPEAASLVAQLSRPQSSK

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9936	-	-

Protein sequence: 313 a.a.

						>T6CP000651 NC_006351:702116-703054 [Burkholderia pseudomallei K96243] [TssA]
MNNDALPGHSPDLLDFDEDFIKIDAAICEYDSVGYAPQRKGESAFQWASIETGCLALLKKAKDVRVGIWHLRACIARRGL
SGLADGVRSLADLMSAPVEELHPRALPDESPGETLLIHLGWLAGPQFLHQLGSSRFEDRDATLNDLIGGRAAAIVEDRDY
RLRANTLVHDIQDSLSRIRESIAAAEQELNVSRALDLLSVAASRLTQAQAGGADGASVESDAPVDAPAGASAPGAQQPMA
GPGGVLRSRQEVGAALDRIVEYFRVHEPSHPAPIFLSRIQRMLGAGFEEVMAELYPEAASLVAQLSRPQSSK*					

Nucleotide sequence: 939 bp

						>T6CP000651 NC_006351:702116-703054 [Burkholderia pseudomallei K96243] [TssA]
ATGAACAACGATGCACTCCCGGGCCATTCGCCGGATTTGCTGGATTTCGACGAAGACTTTATCAAGATCGACGCAGCCAT
CTGCGAATACGATTCCGTCGGTTACGCGCCGCAACGCAAAGGAGAGAGTGCGTTCCAGTGGGCGTCCATCGAAACGGGAT
GTCTCGCTTTGTTGAAGAAGGCGAAGGATGTCCGGGTCGGCATTTGGCATCTGCGCGCATGCATCGCGCGGCGCGGGCTG
AGCGGGCTGGCAGACGGCGTTCGATCGCTGGCCGATCTGATGAGTGCGCCCGTCGAGGAATTGCATCCTCGCGCGCTGCC
TGACGAATCGCCCGGCGAAACCCTCCTGATTCATCTCGGCTGGCTTGCGGGCCCGCAGTTCCTGCATCAGCTCGGCAGTT
CCCGGTTCGAAGACCGGGACGCAACCCTCAACGATCTGATCGGCGGGCGCGCCGCGGCGATCGTGGAGGATCGCGACTAT
CGCCTTAGAGCGAATACTCTTGTACATGACATTCAGGATTCCTTATCGCGAATTCGGGAATCGATCGCCGCGGCCGAGCA
AGAGCTCAACGTCTCGCGCGCGCTCGACCTGTTGAGCGTCGCGGCGTCTCGGCTCACGCAGGCACAAGCCGGCGGCGCGG
ACGGCGCAAGCGTCGAGAGCGACGCGCCGGTCGATGCGCCGGCCGGCGCGTCCGCGCCCGGCGCGCAGCAGCCGATGGCG
GGGCCGGGCGGCGTGTTGAGGTCGAGACAGGAGGTCGGCGCGGCGCTCGATCGGATCGTGGAGTACTTCCGCGTGCACGA
GCCGAGCCATCCGGCGCCGATCTTCCTGTCGCGGATTCAACGAATGCTGGGGGCGGGTTTCGAGGAAGTGATGGCGGAGC
TCTATCCCGAGGCGGCATCTCTCGTGGCCCAACTGAGCCGGCCGCAGAGTTCCAAGTAA					