Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00530  |
| T6SS type | Type i1 |
| Strain | Vibrio furnissii NCTC 11218 |
| Replicon (RefSeq) | chromosome II (NC_016628) |
| Location | 1232863..1256775 |
| Function | - |
| Comment | - |
| References | - |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | PAAR | TssA | TssB | TssC | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM | VasH |
| Number | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| VFU_RS20980 (dmeF) | 1228279..1229184 | + | 906 | WP_041943455.1 | CDF family Co(II)/Ni(II) efflux transporter DmeF | ||
| VFU_RS20985 | 1229195..1229611 | + | 417 | WP_004727200.1 | MarR family transcriptional regulator | ||
| VFU_RS20990 | 1229619..1230206 | - | 588 | WP_004727199.1 | LysE family translocator | ||
| VFU_RS20995 | 1230316..1230759 | + | 444 | WP_014257992.1 | Lrp/AsnC family transcriptional regulator | ||
| T6CP011967 | PAAR | VFU_RS21000 | 1231183..1231467 | + | 285 | WP_004727197.1 | type VI secretion system PAAR protein |
| VFU_RS21005 | 1231451..1232458 | + | 1008 | WP_004727196.1 | sel1 repeat family protein | ||
| T6CP005619 | TssB | VFU_RS21010 (tssB) | 1232863..1233372 | + | 510 | WP_004727195.1 | type VI secretion system contractile sheath small subunit |
| T6CP005620 | TssC | VFU_RS21015 (tssC) | 1233419..1234894 | + | 1476 | WP_004727194.1 | type VI secretion system contractile sheath large subunit |
| T6CP008958 | TssE | VFU_RS21020 (tssE) | 1234897..1235334 | + | 438 | WP_004727193.1 | type VI secretion system baseplate subunit TssE |
| T6CP005621 | TssF | VFU_RS21025 (tssF) | 1235340..1237109 | + | 1770 | WP_014257993.1 | type VI secretion system baseplate subunit TssF |
| T6CP005622 | TssG | VFU_RS21030 (tssG) | 1237073..1238089 | + | 1017 | WP_086027303.1 | type VI secretion system baseplate subunit TssG |
| T6CP011966 | FHA | VFU_RS21035 (tagH) | 1238093..1239580 | + | 1488 | WP_014257994.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP005623 | TssJ | VFU_RS21040 (tssJ) | 1239583..1240059 | + | 477 | WP_004727189.1 | type VI secretion system lipoprotein TssJ |
| T6CP005624 | TssK | VFU_RS21045 (tssK) | 1240066..1241400 | + | 1335 | WP_014257995.1 | type VI secretion system baseplate subunit TssK |
| T6CP005625 | TssL | VFU_RS21050 (vasF) | 1241403..1242176 | + | 774 | WP_014257996.1 | type VI protein secretion system protein VasF |
| T6CP005626 | TssH | VFU_RS21055 (tssH) | 1242203..1244815 | + | 2613 | WP_014257997.1 | type VI secretion system ATPase TssH |
| T6CP012521 | VasH | VFU_RS21060 | 1244818..1246407 | + | 1590 | WP_004727185.1 | sigma-54-dependent Fis family transcriptional regulator |
| VFU_RS21065 (tagO) | 1246452..1247063 | + | 612 | WP_014257998.1 | type VI secretion system-associated protein TagO | ||
| T6CP008959 | TssA | VFU_RS21070 (tssA) | 1247073..1248473 | + | 1401 | WP_014257999.1 | type VI secretion system protein TssA |
| T6CP005627 | TssM | VFU_RS21075 (tssM) | 1248537..1252037 | + | 3501 | WP_193386135.1 | type VI secretion system membrane subunit TssM |
| T6CP008960 | TssA | VFU_RS21080 | 1252090..1253367 | + | 1278 | WP_014258001.1 | ImpA family type VI secretion system protein |
| T6CP005628 | TssI | VFU_RS21085 (tssI) | 1253554..1256775 | + | 3222 | WP_014258002.1 | type VI secretion system tip protein VgrG |
| VFU_RS21090 | 1256781..1257362 | + | 582 | WP_041943306.1 | hypothetical protein | ||
| VFU_RS21095 | 1257464..1257727 | - | 264 | WP_038152245.1 | DUF3012 domain-containing protein | ||
| VFU_RS21100 (rbsD) | 1258136..1258555 | + | 420 | WP_041943457.1 | D-ribose pyranase | ||
| VFU_RS21105 (rbsA) | 1258587..1260092 | + | 1506 | WP_014258006.1 | ribose ABC transporter ATP-binding protein RbsA | ||
| VFU_RS21110 (rbsC) | 1260089..1261072 | + | 984 | WP_014258007.1 | ribose ABC transporter permease |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0001 |
vfu_A02134 (ihfA) | protein | Transcription regulator | Vibrio furnissii NCTC 11218 | chromosome (NC_016602) | 2226951..2227244 (-) | 490864172 | tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓) |
| REG0002 |
vfu_A02422 (ihfB) | protein | Transcription regulator | Vibrio furnissii NCTC 11218 | chromosome (NC_016602) | 2516092..2516376 (-) | 490864456 | tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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