Detailed information of regulator


Summary

Regulator ID REG0114 experimental
Regulator type protein
Regulatory pathway (from literatures) Transcription regulator
KEGG pathway (determined by BlastKOALA) Biofilm formation - Vibrio cholerae (map05111)
Related T6SS T6SS00043 experimental (Type i1)
Strain Vibrio parahaemolyticus RIMD 2210633
Replicon chromosome
Sequence Protein sequence (293 a.a.); Nucleotide sequence (879 bp)
Description ToxR represses the transcription of VP1400-1406 and VP1409-1407 in a direct manner.
Reference
External database links

Locus tag (Gene) VP0820 (ToxR)
Coordinates (Strand) 847892..848770 (-)
NCBI ID 28897594
RefSeq NC_004603
Uniprot ID TOXR_VIBPA
KEGG ID vpa:VP0820
KEGG pathway (determined by BlastKOALA) map05111
PDB ID -
  Target
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Target
Regulation (↓/↑)
Target sequence
VP1400 promotor↑ACGTTGTTGAAATTTTAATTTCTAAAACAACGTAATTCAGGTAGTGAAAAGCGTAAGTCAAAGAGTCTAATAACTTAGTAATTATAACTAAAATAATAGGC
VP1409 promotor↑GAATACAATAAAAAAATCTATCTTTATTATTTTATTAT
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Pfam domain hit(s) of regulator

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Domain
Pfam ID
E-value
Aligned region
Trans_reg_CPF00486.301e-1931..107
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Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

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Prediction                
Region    
Sequence
Outside1-292MTNIGTKFLLAQRFTFDPNSNSLADQQSGNEVVRLGSNESRILLMLAERPNEVLTRNELHEFVWREQGFEVDDSSLTQAISTLRKMLKDSTKSPEFVKTVPKRGYQLICTVERLSPLSSDSSSIEVEEPASDNNDASANEVETIVEPSLATTSDAIVEPEAPVVPEKAPVASAVNPWIPRVILFLALLLPICVLLFTNPAESQFRQIGEYQNVPVMTPVNHPQINNWLPSIEQCIERYVKHHAEDSLPVEVIATGGQNNQLILNYIHDSNHSYENVTLRIFAGQNDPTDICK


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
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Prediction       
Probability
Cleavage site
Signal peptide sequence
Other0.9893--


  Protein sequence of regulator: 293 a.a.    .

>REG0114 NC_004603:c848770-847892 [Vibrio parahaemolyticus RIMD 2210633]
MTNIGTKFLLAQRFTFDPNSNSLADQQSGNEVVRLGSNESRILLMLAERPNEVLTRNELHEFVWREQGFEVDDSSLTQAI
STLRKMLKDSTKSPEFVKTVPKRGYQLICTVERLSPLSSDSSSIEVEEPASDNNDASANEVETIVEPSLATTSDAIVEPE
APVVPEKAPVASAVNPWIPRVILFLALLLPICVLLFTNPAESQFRQIGEYQNVPVMTPVNHPQINNWLPSIEQCIERYVK
HHAEDSLPVEVIATGGQNNQLILNYIHDSNHSYENVTLRIFAGQNDPTDICK*

  Nucleotide sequence of regulator: 879 bp    .

>REG0114 NC_004603:c848770-847892 [Vibrio parahaemolyticus RIMD 2210633]
ATGACTAACATCGGCACCAAATTTCTACTTGCTCAAAGGTTTACCTTTGATCCAAATAGTAATTCGCTCGCTGACCAACA
AAGCGGCAACGAAGTTGTACGATTAGGAAGCAACGAAAGCCGTATACTCCTGATGTTGGCGGAGAGACCAAACGAAGTTT
TAACCCGTAACGAGCTTCACGAGTTTGTTTGGCGTGAGCAAGGTTTTGAGGTGGATGACTCAAGCCTGACTCAAGCGATT
TCTACTCTGCGTAAGATGTTGAAGGATTCAACCAAATCTCCAGAGTTTGTTAAAACCGTTCCAAAACGAGGCTATCAACT
CATTTGTACTGTTGAACGCCTAAGCCCGCTTTCTTCAGACTCAAGCTCAATTGAAGTTGAAGAGCCAGCTTCTGATAACA
ATGACGCCTCTGCTAATGAGGTAGAAACAATCGTAGAGCCGTCTTTAGCGACGACTTCTGACGCAATCGTTGAACCAGAA
GCGCCAGTAGTACCTGAAAAAGCACCTGTGGCTTCTGCTGTGAATCCTTGGATTCCACGCGTTATTTTATTTTTGGCACT
ATTACTACCGATTTGCGTACTGCTGTTTACAAACCCAGCGGAATCTCAGTTCCGTCAGATTGGTGAGTATCAGAACGTAC
CAGTGATGACACCTGTAAATCACCCGCAAATCAACAACTGGTTGCCTTCTATTGAGCAGTGCATTGAACGCTACGTTAAG
CACCATGCAGAAGACTCGTTACCAGTGGAAGTAATTGCCACTGGCGGACAAAATAACCAGCTGATTTTGAACTACATTCA
TGACAGCAACCACTCGTATGAGAACGTGACATTGCGTATTTTCGCAGGTCAAAATGATCCAACAGACATCTGCAAATAA