Detailed information of regulator
Summary
Regulator ID | REG0114 |
Regulator type | protein |
Regulatory pathway (from literatures) | Transcription regulator |
KEGG pathway (determined by BlastKOALA) | Biofilm formation - Vibrio cholerae (map05111) |
Related T6SS | T6SS00043 (Type i1) |
Strain | Vibrio parahaemolyticus RIMD 2210633 |
Replicon | chromosome |
Sequence | Protein sequence (293 a.a.); Nucleotide sequence (879 bp) |
Description | ToxR represses the transcription of VP1400-1406 and VP1409-1407 in a direct manner. |
Reference |
External database links
Locus tag (Gene) | VP0820 (ToxR) |
Coordinates (Strand) | 847892..848770 (-) |
NCBI ID | 28897594 |
RefSeq | NC_004603 |
Uniprot ID | TOXR_VIBPA |
KEGG ID | vpa:VP0820 |
KEGG pathway (determined by BlastKOALA) | map05111 |
PDB ID | - |
Target
Target | Regulation (↓/↑) | Target sequence |
---|---|---|
VP1400 promotor | ↑ | ACGTTGTTGAAATTTTAATTTCTAAAACAACGTAATTCAGGTAGTGAAAAGCGTAAGTCAAAGAGTCTAATAACTTAGTAATTATAACTAAAATAATAGGC |
VP1409 promotor | ↑ | GAATACAATAAAAAAATCTATCTTTATTATTTTATTAT |
Pfam domain hit(s) of regulator
Domain | Pfam ID | E-value | Aligned region |
---|---|---|---|
Trans_reg_C | PF00486.30 | 1e-19 | 31..107 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
Prediction | Region | Sequence |
---|---|---|
Outside | 1-292 | MTNIGTKFLLAQRFTFDPNSNSLADQQSGNEVVRLGSNESRILLMLAERPNEVLTRNELHEFVWREQGFEVDDSSLTQAISTLRKMLKDSTKSPEFVKTVPKRGYQLICTVERLSPLSSDSSSIEVEEPASDNNDASANEVETIVEPSLATTSDAIVEPEAPVVPEKAPVASAVNPWIPRVILFLALLLPICVLLFTNPAESQFRQIGEYQNVPVMTPVNHPQINNWLPSIEQCIERYVKHHAEDSLPVEVIATGGQNNQLILNYIHDSNHSYENVTLRIFAGQNDPTDICK |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction | Probability | Cleavage site | Signal peptide sequence |
---|---|---|---|
Other | 0.9893 | - | - |
Protein sequence of regulator: 293 a.a. .
>REG0114 NC_004603:c848770-847892 [Vibrio parahaemolyticus RIMD 2210633]
MTNIGTKFLLAQRFTFDPNSNSLADQQSGNEVVRLGSNESRILLMLAERPNEVLTRNELHEFVWREQGFEVDDSSLTQAI
STLRKMLKDSTKSPEFVKTVPKRGYQLICTVERLSPLSSDSSSIEVEEPASDNNDASANEVETIVEPSLATTSDAIVEPE
APVVPEKAPVASAVNPWIPRVILFLALLLPICVLLFTNPAESQFRQIGEYQNVPVMTPVNHPQINNWLPSIEQCIERYVK
HHAEDSLPVEVIATGGQNNQLILNYIHDSNHSYENVTLRIFAGQNDPTDICK*
MTNIGTKFLLAQRFTFDPNSNSLADQQSGNEVVRLGSNESRILLMLAERPNEVLTRNELHEFVWREQGFEVDDSSLTQAI
STLRKMLKDSTKSPEFVKTVPKRGYQLICTVERLSPLSSDSSSIEVEEPASDNNDASANEVETIVEPSLATTSDAIVEPE
APVVPEKAPVASAVNPWIPRVILFLALLLPICVLLFTNPAESQFRQIGEYQNVPVMTPVNHPQINNWLPSIEQCIERYVK
HHAEDSLPVEVIATGGQNNQLILNYIHDSNHSYENVTLRIFAGQNDPTDICK*
Nucleotide sequence of regulator: 879 bp .
>REG0114 NC_004603:c848770-847892 [Vibrio parahaemolyticus RIMD 2210633]
ATGACTAACATCGGCACCAAATTTCTACTTGCTCAAAGGTTTACCTTTGATCCAAATAGTAATTCGCTCGCTGACCAACA
AAGCGGCAACGAAGTTGTACGATTAGGAAGCAACGAAAGCCGTATACTCCTGATGTTGGCGGAGAGACCAAACGAAGTTT
TAACCCGTAACGAGCTTCACGAGTTTGTTTGGCGTGAGCAAGGTTTTGAGGTGGATGACTCAAGCCTGACTCAAGCGATT
TCTACTCTGCGTAAGATGTTGAAGGATTCAACCAAATCTCCAGAGTTTGTTAAAACCGTTCCAAAACGAGGCTATCAACT
CATTTGTACTGTTGAACGCCTAAGCCCGCTTTCTTCAGACTCAAGCTCAATTGAAGTTGAAGAGCCAGCTTCTGATAACA
ATGACGCCTCTGCTAATGAGGTAGAAACAATCGTAGAGCCGTCTTTAGCGACGACTTCTGACGCAATCGTTGAACCAGAA
GCGCCAGTAGTACCTGAAAAAGCACCTGTGGCTTCTGCTGTGAATCCTTGGATTCCACGCGTTATTTTATTTTTGGCACT
ATTACTACCGATTTGCGTACTGCTGTTTACAAACCCAGCGGAATCTCAGTTCCGTCAGATTGGTGAGTATCAGAACGTAC
CAGTGATGACACCTGTAAATCACCCGCAAATCAACAACTGGTTGCCTTCTATTGAGCAGTGCATTGAACGCTACGTTAAG
CACCATGCAGAAGACTCGTTACCAGTGGAAGTAATTGCCACTGGCGGACAAAATAACCAGCTGATTTTGAACTACATTCA
TGACAGCAACCACTCGTATGAGAACGTGACATTGCGTATTTTCGCAGGTCAAAATGATCCAACAGACATCTGCAAATAA
ATGACTAACATCGGCACCAAATTTCTACTTGCTCAAAGGTTTACCTTTGATCCAAATAGTAATTCGCTCGCTGACCAACA
AAGCGGCAACGAAGTTGTACGATTAGGAAGCAACGAAAGCCGTATACTCCTGATGTTGGCGGAGAGACCAAACGAAGTTT
TAACCCGTAACGAGCTTCACGAGTTTGTTTGGCGTGAGCAAGGTTTTGAGGTGGATGACTCAAGCCTGACTCAAGCGATT
TCTACTCTGCGTAAGATGTTGAAGGATTCAACCAAATCTCCAGAGTTTGTTAAAACCGTTCCAAAACGAGGCTATCAACT
CATTTGTACTGTTGAACGCCTAAGCCCGCTTTCTTCAGACTCAAGCTCAATTGAAGTTGAAGAGCCAGCTTCTGATAACA
ATGACGCCTCTGCTAATGAGGTAGAAACAATCGTAGAGCCGTCTTTAGCGACGACTTCTGACGCAATCGTTGAACCAGAA
GCGCCAGTAGTACCTGAAAAAGCACCTGTGGCTTCTGCTGTGAATCCTTGGATTCCACGCGTTATTTTATTTTTGGCACT
ATTACTACCGATTTGCGTACTGCTGTTTACAAACCCAGCGGAATCTCAGTTCCGTCAGATTGGTGAGTATCAGAACGTAC
CAGTGATGACACCTGTAAATCACCCGCAAATCAACAACTGGTTGCCTTCTATTGAGCAGTGCATTGAACGCTACGTTAAG
CACCATGCAGAAGACTCGTTACCAGTGGAAGTAATTGCCACTGGCGGACAAAATAACCAGCTGATTTTGAACTACATTCA
TGACAGCAACCACTCGTATGAGAACGTGACATTGCGTATTTTCGCAGGTCAAAATGATCCAACAGACATCTGCAAATAA