Detailed information of regulator


Summary

Regulator ID REG0030 experimental
Regulator type protein
Regulatory pathway (from literatures) Global regulator
KEGG pathway (determined by BlastKOALA) Biofilm formation - Escherichia coli (map02026)
Related T6SS T6SS01168 experimental (Type i1)
Strain Vibrio cholerae C6706
Replicon chromosome
Sequence Protein sequence (215 a.a.); Nucleotide sequence (645 bp)
Description T6SS-mediated killing are positively regulated by CytR, TfoX, HapR, and QstR.
Reference

External database links

Locus tag (Gene) GPY04_RS13825 (QstR)
Coordinates (Strand) 2994333..2994977 (-)
NCBI ID 447111060
RefSeq NZ_CP046844
Uniprot ID Q9KUW3_VIBCH, A0A0X1L2N3_VIBCO, A0A0H3ALH4_VIBC3, D7HD98_VIBCL, A0A0K9UMZ8_VIBCL, A0A0H3Q739_VIBCL, C3LRC7_VIBCM, A0A0H6R3E4_VIBCL
KEGG ID vco:VC0395_A2814, vcq:EN18_18975, vch:VC0396, vcm:VCM66_0381
KEGG pathway (determined by BlastKOALA) map02026
PDB ID -

  Target
Target Regulation (↓/↑) Target sequence
Unknown -

Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
GerE PF00196.21 3e-20 155..208

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-214 MQRANYARTIYLLTTQPKALHPSIQAAIEQLNLPVPVIEPERLLREYQSDKHKILLLDHAENGLIRQQLGPLKLTSPYFETILFNVEKRLRTEDLLTFGNLKGLFYANEDTGFIAHGLGEIINGQNWLPRHVSSQLLHYYRYAFQSHQVQATVDLTAREIQILRCLQTGASNMQIAENLFISEFTVKSHLYQIFKKLNVKNRVKAIAWVNQNLL



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8457 - -



  Protein sequence of regulator: 215 a.a.    .

>REG0030 NZ_CP046844:c2994977-2994333 [Vibrio cholerae C6706]
MQRANYARTIYLLTTQPKALHPSIQAAIEQLNLPVPVIEPERLLREYQSDKHKILLLDHAENGLIRQQLGPLKLTSPYFE
TILFNVEKRLRTEDLLTFGNLKGLFYANEDTGFIAHGLGEIINGQNWLPRHVSSQLLHYYRYAFQSHQVQATVDLTAREI
QILRCLQTGASNMQIAENLFISEFTVKSHLYQIFKKLNVKNRVKAIAWVNQNLL*

  Nucleotide sequence of regulator: 645 bp    .

>REG0030 NZ_CP046844:c2994977-2994333 [Vibrio cholerae C6706]
ATGCAACGAGCCAACTATGCACGCACGATTTATTTATTAACGACACAGCCAAAAGCGTTACATCCCAGTATTCAAGCCGC
CATTGAGCAGTTGAATCTGCCCGTCCCGGTGATTGAACCAGAACGCTTATTGCGCGAGTATCAATCCGATAAACACAAAA
TATTGTTGCTCGACCATGCGGAAAATGGCCTGATTCGCCAGCAATTGGGTCCCCTAAAGCTTACCAGCCCGTACTTCGAA
ACCATCTTGTTTAATGTCGAGAAACGGTTAAGAACAGAAGATCTGCTCACTTTTGGCAACCTCAAAGGTCTGTTTTATGC
CAATGAAGACACAGGCTTTATTGCCCACGGTCTTGGGGAGATCATTAATGGCCAAAACTGGCTACCTCGCCATGTCAGCA
GTCAGTTGCTGCATTACTATCGTTACGCTTTCCAAAGCCATCAAGTTCAAGCCACGGTCGATTTGACTGCACGTGAAATT
CAGATCCTGCGCTGTTTACAAACTGGCGCATCGAATATGCAAATCGCTGAGAATTTATTTATTAGTGAGTTCACGGTGAA
ATCGCATCTTTATCAGATATTTAAAAAGCTAAACGTGAAAAATCGAGTCAAAGCGATCGCTTGGGTTAATCAAAATTTAC
TGTAA