Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01251  |
| T6SS type | Type i1 |
| Strain | Vibrio parahaemolyticus strain D4 |
| Replicon (RefSeq) | chromosome (NZ_NNJE01000075) |
| Location | 1500..20954 |
| Function | anti-bacterial |
| Comment | T6SS can secrete hcp at 27°C, T6SS1 can secrete VGRG and show bactericidal activity. |
| References | [1] Li P, Kinch LN, Ray A, Dalia AB, Cong Q, Nunan LM, Camilli A, Grishin NV, Salomon D, Orth K. et al (2017) Acute Hepatopancreatic Necrosis Disease-Causing Vibrio parahaemolyticus Strains Maintain an Antibacterial Type VI Secretion System with Versatile Effector Repertoires.. Appl Environ Microbiol. 83(13). [PudMed:28432099] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssI | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| CGI87_RS23430 | 168..1478 | + | 1311 | 657846575 | type VI secretion system ImpA family N-terminal domain-containing protein | ||
| T6CP015674 | TssM | CGI87_RS23435 (tssM) | 1500..4889 | + | 3390 | 527097408 | type VI secretion system membrane subunit TssM |
| CGI87_RS23440 | 4922..5374 | + | 453 | 491623128 | Lrp/AsnC family transcriptional regulator | ||
| T6CP015675 | TssG | CGI87_RS23445 (tssG) | 5438..6436 | - | 999 | 505109571 | type VI secretion system baseplate subunit TssG |
| T6CP015676 | TssF | CGI87_RS23450 (tssF) | 6433..8181 | - | 1749 | 491623126 | type VI secretion system baseplate subunit TssF |
| T6CP015677 | TssE | CGI87_RS23455 (tssE) | 8192..8602 | - | 411 | 491623044 | type VI secretion system baseplate subunit TssE |
| T6CP015678 | TssC | CGI87_RS23460 (tssC) | 8664..10139 | - | 1476 | 491623191 | type VI secretion system contractile sheath large subunit |
| T6CP015679 | TssB | CGI87_RS23465 (tssB) | 10148..10654 | - | 507 | 527097409 | type VI secretion system contractile sheath small subunit |
| T6CP015680 | TssA | CGI87_RS23470 (tssA) | 10681..12255 | - | 1575 | 527097410 | type VI secretion system protein TssA |
| CGI87_RS23475 | 12255..14258 | - | 2004 | 657846570 | protein kinase family protein | ||
| CGI87_RS23480 | 14493..15437 | - | 945 | 527097412 | hypothetical protein | ||
| CGI87_RS23485 | 15430..16422 | - | 993 | 527097413 | DUF2169 domain-containing protein | ||
| CGI87_RS23490 | 16403..17722 | - | 1320 | 527097414 | hypothetical protein | ||
| CGI87_RS23495 | 17800..18285 | - | 486 | 527097415 | hypothetical protein | ||
| T6CP015681 | TssI | CGI87_RS23500 (tssI) | 18285..20363 | - | 2079 | 527097416 | type VI secretion system tip protein VgrG |
| T6CP015682 | TssD | CGI87_RS23505 | 20436..20954 | - | 519 | 491623110 | Hcp family type VI secretion system effector |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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