Detailed information of regulator


Summary

Regulator ID REG0115 experimental
Regulator type protein
Regulatory pathway (from literatures) Transcription regulator
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00044 experimental (Type i5)
Strain Vibrio parahaemolyticus RIMD 2210633
Replicon chromosome
Sequence Protein sequence (320 a.a.); Nucleotide sequence (960 bp)
Description CalR activates the promoter activities of T6SS2 genes,and antagonise H-NS.
Reference
External database links

Locus tag (Gene) VP0350 (CalR/LeuO)
Coordinates (Strand) 344763..345722 (+)
NCBI ID 28897124
RefSeq NC_004603
Uniprot ID Q87SS2_VIBPA
KEGG ID vpa:VP0350
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
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Target
Regulation (↓/↑)
Target sequence
VPA1027 (hcp2) promotor↓tgcttcacggtccattgctgtacccgtgtaagaagaaatttcacgaccaacactccaatctacagatagtagtgtaattaaatccttatattgttccgctgtcgcttcacctttaatatctgcgtatttaagatacgtattagactgcatgctaatctcctagagcattattaattgacatatttcgtattaattaaattatctgaataatgataattaatgattgatgtatcaaaaacttcattttaaatacgctcctttatatctttaaattagatttaaattaagcgatatttataactaataatagttattatgaagcaactctcaattattatttacagagttaaacttgttaaataagtgagacttctagttctttaattgaacctctaacattaatttcatcgaacgtcttaccattaagaattgcattcaatatttcatgagaaattttaggaagtaaattattttcaatggtggtttgaactacacgagcaccacttcctgactcattactattgtctacaatgtcattaattagttgttcatcaaaatacaaccctgccgaataatgttttcggatacggttagatactttgttgagttttaacttagttatttccgttaggacttcttttccgagaggcaagtaaggtaata
VPA1043 (Fha) promotor↓tgagcgtccgaaggttacctttgcatgctcatcacttgattcaaacacaaactcactctctatttccggagtaaatttgtggaaactcgttatggtcaataccaatttcatgaaaaacctcgccaaagacctgctaaatatttatatatcgatttttataattagatttgaagctttaattattaacattaagattaatagagttcttatagctgttataaaaactattgacggcataatgaatcatttttttatcaaagcaatcatgaattgttgaacaattttaaatatccaaccaggttcaaatttttgacactcaaactttcacccgtcaaaaaaccgatgttagtttggccgagaaaatctaaccgaagtatttttcatttagcaggaatatatatattaaccccatcatttatatggagtccttgtgatggaagaaaaaaataaagacaaatctataaatagcagcgatagcggagataaaacaaaaattgtaaagactcaaaaaagagaaaatgcaattgaacccgctaaaaacgttaataaacaagactccgctgaaaatataaatgaaacggatacaaaactgtctcaaaaagaaaacacaataccacctatcaacaaa
VP1133 (H-NS)↓-
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Pfam domain hit(s) of regulator

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Domain
Pfam ID
E-value
Aligned region
LysR_substratePF03466.221.1e-23119..307
HTH_1PF00126.295.2e-1825..83
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Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

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Prediction                
Region    
Sequence
Outside1-319MLEKKDAMSAIASYRMESTLRGVDLNLLTVFDAVMQEQNITRAAHNLGMSQPAVSNAVARLKVMFNDELFMRQGRGIQPTQRARQLFGPIRQALQLIRNELPSSVFQPESSTRLFKLAICSPCDMRFAPKIMAKINQQAPNVQLHLDAEFDRLLSERMRYQEIDFVIDYARFDEQGFSSTEIFKDELVVIASKTHPRIQGGVSAEQLINEKHAKLSKVHGQRSFSEQAYRELDCQAAYEGSSLSNLLYVVSQSELVTIAPRWMAENAVNSDQLQILDFPFANKEISGFLSWHESSEKDKGHIWLRDQLMVTCGEVVASK


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
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Prediction       
Probability
Cleavage site
Signal peptide sequence
Other0.9881--


  Protein sequence of regulator: 320 a.a.    .

>REG0115 NC_004603:344763-345722 [Vibrio parahaemolyticus RIMD 2210633]
MLEKKDAMSAIASYRMESTLRGVDLNLLTVFDAVMQEQNITRAAHNLGMSQPAVSNAVARLKVMFNDELFMRQGRGIQPT
QRARQLFGPIRQALQLIRNELPSSVFQPESSTRLFKLAICSPCDMRFAPKIMAKINQQAPNVQLHLDAEFDRLLSERMRY
QEIDFVIDYARFDEQGFSSTEIFKDELVVIASKTHPRIQGGVSAEQLINEKHAKLSKVHGQRSFSEQAYRELDCQAAYEG
SSLSNLLYVVSQSELVTIAPRWMAENAVNSDQLQILDFPFANKEISGFLSWHESSEKDKGHIWLRDQLMVTCGEVVASK*

  Nucleotide sequence of regulator: 960 bp    .

>REG0115 NC_004603:344763-345722 [Vibrio parahaemolyticus RIMD 2210633]
ATGTTAGAGAAGAAAGATGCGATGAGCGCAATTGCTAGCTACCGTATGGAAAGCACTTTGCGTGGTGTAGATTTGAACCT
ACTGACTGTATTTGATGCTGTGATGCAAGAGCAAAATATCACTCGTGCAGCACACAACTTAGGCATGTCTCAACCGGCAG
TAAGTAATGCCGTGGCACGTCTAAAAGTGATGTTTAACGATGAACTGTTCATGCGTCAGGGCCGTGGTATTCAACCAACT
CAACGTGCGCGTCAACTGTTTGGCCCTATCCGCCAAGCATTGCAACTGATCCGTAACGAATTGCCAAGCTCGGTATTCCA
ACCAGAGTCGTCAACTCGTCTATTCAAGCTGGCGATTTGCAGCCCATGTGACATGCGCTTTGCTCCAAAAATCATGGCGA
AGATTAATCAACAAGCGCCAAACGTTCAGCTACATCTAGACGCGGAATTTGACCGTCTTCTTTCTGAGCGCATGCGTTAC
CAAGAAATCGACTTCGTGATCGATTACGCTCGTTTTGATGAGCAAGGTTTCTCAAGCACAGAAATTTTCAAAGATGAATT
GGTGGTTATCGCTTCGAAAACGCACCCACGTATTCAAGGTGGCGTAAGCGCCGAGCAGCTAATTAACGAAAAGCACGCGA
AACTGTCTAAAGTTCACGGTCAACGTAGCTTCTCTGAGCAGGCGTACCGCGAGCTTGACTGCCAAGCTGCGTACGAAGGT
TCAAGCCTAAGCAACTTGCTTTACGTCGTTAGCCAATCTGAGTTAGTGACTATCGCACCACGCTGGATGGCGGAAAATGC
GGTGAACAGTGACCAACTGCAGATTCTAGACTTCCCATTTGCGAACAAAGAAATCAGCGGCTTCCTTAGCTGGCATGAAT
CAAGTGAAAAAGACAAAGGCCACATTTGGCTACGTGACCAGCTAATGGTGACGTGTGGTGAAGTGGTCGCATCAAAATAA