Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01254  |
| T6SS type | Type i1 |
| Strain | Vibrio parahaemolyticus strain 12-009A/1335 |
| Replicon (RefSeq) | chromosome (NZ_MYFF01000478) |
| Location | 10921..33508 |
| Function | anti-bacterial |
| Comment | T6SS1 can secrete VGRG and the activity was required for the observed bactericidal activity at 30°C |
| References | [1] Li P, Kinch LN, Ray A, Dalia AB, Cong Q, Nunan LM, Camilli A, Grishin NV, Salomon D, Orth K. et al (2017) Acute Hepatopancreatic Necrosis Disease-Causing Vibrio parahaemolyticus Strains Maintain an Antibacterial Type VI Secretion System with Versatile Effector Repertoires.. Appl Environ Microbiol. 83(13). [PudMed:28432099] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| B5C29_RS17055 | 9303..10934 | - | 1632 | 686279246 | sigma-54-dependent Fis family transcriptional regulator | ||
| T6CP015712 | TssH | B5C29_RS17060 (tssH) | 10921..13599 | - | 2679 | 1189147610 | type VI secretion system ATPase TssH |
| T6CP015713 | TssD | B5C29_RS17065 | 14054..14572 | + | 519 | 491623110 | Hcp family type VI secretion system effector |
| T6CP015714 | TssI | B5C29_RS17070 (tssI) | 14645..16723 | + | 2079 | 686279245 | type VI secretion system tip protein VgrG |
| B5C29_RS17075 | 16723..17208 | + | 486 | 527097415 | hypothetical protein | ||
| B5C29_RS17080 | 17286..18605 | + | 1320 | 658972708 | hypothetical protein | ||
| B5C29_RS17085 | 18586..19578 | + | 993 | 647015937 | DUF2169 domain-containing protein | ||
| B5C29_RS17090 | 19571..20515 | + | 945 | 1189147605 | hypothetical protein | ||
| B5C29_RS17095 | 20750..22753 | + | 2004 | 646736342 | protein kinase family protein | ||
| T6CP015715 | TssA | B5C29_RS17100 (tssA) | 22753..24327 | + | 1575 | 1189147606 | type VI secretion system protein TssA |
| T6CP015716 | TssB | B5C29_RS17105 (tssB) | 24354..24860 | + | 507 | 491623049 | type VI secretion system contractile sheath small subunit |
| T6CP015717 | TssC | B5C29_RS17110 (tssC) | 24869..26344 | + | 1476 | 686279244 | type VI secretion system contractile sheath large subunit |
| T6CP015718 | TssE | B5C29_RS17115 (tssE) | 26406..26816 | + | 411 | 491623044 | type VI secretion system baseplate subunit TssE |
| T6CP015719 | TssF | B5C29_RS17120 (tssF) | 26827..28575 | + | 1749 | 491623126 | type VI secretion system baseplate subunit TssF |
| T6CP015720 | TssG | B5C29_RS17125 (tssG) | 28572..29570 | + | 999 | 646487891 | type VI secretion system baseplate subunit TssG |
| B5C29_RS17130 | 29634..30086 | - | 453 | 491623128 | Lrp/AsnC family transcriptional regulator | ||
| T6CP015721 | TssM | B5C29_RS17135 (tssM) | 30119..33508 | - | 3390 | 1189147607 | type VI secretion system membrane subunit TssM |
| B5C29_RS17140 | 33530..34825 | - | 1296 | 646452597 | type VI secretion system ImpA family N-terminal domain-containing protein | ||
| B5C29_RS17145 | 35345..35944 | + | 600 | 646480479 | hypothetical protein | ||
| B5C29_RS17150 | 35954..36714 | + | 761 | 1691674928 | FHA domain-containing protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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