Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00084  |
| T6SS type | Type i1 |
| Strain | Aliivibrio fischeri ES114 |
| Replicon (RefSeq) | chromosome I (NC_006840) |
| Location | 1087244..1118010 |
| Function | anti-bacterial |
| Comment | T6SS is a functional antibacterial system. |
| References | [1] Guckes KR, Cecere AG, Wasilko NP, Williams AL, Bultman KM, Mandel MJ, Miyashiro T. et al (2019) Incompatibility of Vibrio fischeri Strains during Symbiosis Establishment Depends on Two Functionally Redundant hcp Genes.. J Bacteriol. 201(19). [PudMed:31331977] [2] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TssB | TssC | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| VF_RS05155 | 1085721..1087673 | + | 1953 | WP_011261623.1 | methyl-accepting chemotaxis protein | ||
| VF_RS05165 | 1088147..1088896 | + | 750 | WP_011261624.1 | DUF481 domain-containing protein | ||
| VF_RS05170 | 1089083..1090978 | + | 1896 | WP_011261625.1 | sensor domain-containing diguanylate cyclase | ||
| VF_RS05175 | 1090979..1091938 | - | 960 | WP_011261626.1 | serine/threonine protein kinase | ||
| VF_RS05180 | 1091935..1092606 | - | 672 | WP_005418697.1 | serine/threonine-protein phosphatase | ||
| T6CP000746 | TssM | VF_RS05185 (tssM) | 1092603..1096124 | - | 3522 | WP_011261627.1 | type VI secretion system membrane subunit TssM |
| T6CP000747 | TssL | VF_RS05190 (icmH) | 1096135..1096968 | - | 834 | WP_005418702.1 | type IVB secretion system protein IcmH/DotU |
| T6CP000748 | TssK | VF_RS05195 (tssK) | 1096970..1098292 | - | 1323 | WP_011261628.1 | type VI secretion system baseplate subunit TssK |
| T6CP000749 | TssJ | VF_RS05200 (tssJ) | 1098304..1098795 | - | 492 | WP_011261629.1 | type VI secretion system lipoprotein TssJ |
| T6CP011472 | FHA | VF_RS05205 (tagH) | 1098832..1100142 | - | 1311 | WP_011261630.1 | type VI secretion system-associated FHA domain protein TagH |
| VF_RS05210 | 1100277..1101845 | - | 1569 | WP_011261631.1 | sigma-54 dependent transcriptional regulator | ||
| T6CP000750 | TssH | VF_RS05215 (tssH) | 1101851..1104433 | - | 2583 | WP_011261632.1 | type VI secretion system ATPase TssH |
| T6CP000751 | TssG | VF_RS05220 (tssG) | 1104430..1105470 | - | 1041 | WP_011261633.1 | type VI secretion system baseplate subunit TssG |
| T6CP000752 | TssF | VF_RS05225 (tssF) | 1105434..1107185 | - | 1752 | WP_011261634.1 | type VI secretion system baseplate subunit TssF |
| T6CP008464 | TssE | VF_RS05230 (tssE) | 1107182..1107607 | - | 426 | WP_011261635.1 | type VI secretion system baseplate subunit TssE |
| T6CP000753 | TssC | VF_RS05235 (tssC) | 1107697..1109172 | - | 1476 | WP_011261636.1 | type VI secretion system contractile sheath large subunit |
| T6CP000754 | TssB | VF_RS05240 (tssB) | 1109176..1109676 | - | 501 | WP_005418723.1 | type VI secretion system contractile sheath small subunit |
| VF_RS05245 (tssA) | 1109692..1111242 | - | 1551 | WP_011261637.1 | type VI secretion system protein TssA | ||
| VF_RS05250 (rsmS) | 1111465..1111671 | - | 207 | WP_011261638.1 | pleiotropic regulatory protein RsmS | ||
| VF_RS05255 | 1111664..1112215 | - | 552 | WP_011261639.1 | primosomal replication protein | ||
| VF_RS05260 | 1112226..1112996 | - | 771 | WP_011261640.1 | TSUP family transporter | ||
| VF_RS05265 (dinG) | 1113065..1115149 | - | 2085 | WP_011261641.1 | ATP-dependent DNA helicase DinG | ||
| VF_RS05270 | 1115673..1116692 | + | 1020 | WP_047863458.1 | porin | ||
| VF_RS05275 | 1117330..1118388 | + | 1059 | WP_011261643.1 | porin | ||
| VF_RS05280 (hisG) | 1118853..1119749 | + | 897 | WP_011261645.1 | ATP phosphoribosyltransferase | ||
| VF_RS05285 (hisD) | 1119755..1121074 | + | 1320 | WP_011261646.1 | histidinol dehydrogenase | ||
| VF_RS05290 | 1121084..1122124 | + | 1041 | WP_011261647.1 | histidinol-phosphate transaminase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0122 |
VF2177 (LitR) | protein | QS regulatory pathway | Aliivibrio fischeri ES114 | chromosome (NC_006840) | 2446537..2447142 (+) | 59712784 | Unknown (↓) |
| REG0123 |
VF0896 (TfoX) | protein | Global regulator | Aliivibrio fischeri ES114 | chromosome (NC_006840) | 986000..986629 (+) | 59711503 | T6SS transcripts (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|