Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01280  |
| T6SS type | Type i5 |
| Strain | Vibrio coralliilyticus OCN008 |
| Replicon (RefSeq) | chromosome I (NZ_CP048693) |
| Location | 2761384..2787511 |
| Function | anti-bacterial |
| Comment | V. coralliilyticus has a functional which showed effective at killing V.cholerae and required for resistance to T6SS-mediated killing by V.cholerae |
| References | [1] Guillemette R, Ushijima B, Jalan M, H |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| G3U99_RS13095 (prpC) | 2757248..2758375 | - | 1128 | WP_021458179.1 | 2-methylcitrate synthase | ||
| G3U99_RS13100 (prpB) | 2758498..2759394 | - | 897 | WP_021458178.1 | methylisocitrate lyase | ||
| G3U99_RS13105 | 2759407..2760111 | - | 705 | WP_021458177.1 | GntR family transcriptional regulator | ||
| G3U99_RS13110 | 2760393..2761190 | + | 798 | WP_165579724.1 | hypothetical protein | ||
| T6CP015896 | TssI | G3U99_RS13115 (tssI) | 2761384..2763366 | + | 1983 | WP_021458175.1 | type VI secretion system tip protein VgrG |
| G3U99_RS13120 | 2763368..2763940 | + | 573 | WP_029236348.1 | hypothetical protein | ||
| G3U99_RS13125 | 2763937..2764239 | + | 303 | WP_019278072.1 | PAAR domain-containing protein | ||
| T6CP015897 | TssA | G3U99_RS13130 | 2764636..2766039 | + | 1404 | WP_021458174.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP015898 | TssD | G3U99_RS13135 | 2766074..2766595 | + | 522 | WP_006962090.1 | type VI secretion system tube protein Hcp |
| T6CP015899 | TssB | G3U99_RS13140 (tssB) | 2766615..2767121 | + | 507 | WP_006962089.1 | type VI secretion system contractile sheath small subunit |
| T6CP015900 | TssC | G3U99_RS13145 (tssC) | 2767118..2768596 | + | 1479 | WP_006962088.1 | type VI secretion system contractile sheath large subunit |
| G3U99_RS13150 | 2768658..2770052 | + | 1395 | WP_165579638.1 | type VI secretion system contractile sheath large subunit | ||
| T6CP015901 | TssE | G3U99_RS13155 (tssE) | 2770052..2770474 | + | 423 | WP_021457559.1 | type VI secretion system baseplate subunit TssE |
| T6CP015902 | TssF | G3U99_RS13160 (tssF) | 2770467..2772218 | + | 1752 | WP_021457560.1 | type VI secretion system baseplate subunit TssF |
| T6CP015903 | TssG | G3U99_RS13165 | 2772239..2773168 | + | 930 | WP_006962084.1 | type VI secretion system baseplate subunit TssG |
| T6CP015904 | TssH | G3U99_RS13170 (tssH) | 2773243..2775855 | + | 2613 | WP_165579639.1 | type VI secretion system ATPase TssH |
| G3U99_RS13175 | 2775875..2778424 | + | 2550 | WP_031343067.1 | MFS transporter | ||
| G3U99_RS13180 | 2778421..2779422 | + | 1002 | WP_006962081.1 | ABC transporter substrate-binding protein | ||
| G3U99_RS13185 | 2779410..2780132 | + | 723 | WP_021457562.1 | transporter substrate-binding domain-containing protein | ||
| G3U99_RS13190 | 2780136..2781080 | + | 945 | WP_031343071.1 | FHA domain-containing protein | ||
| T6CP015905 | TssJ | G3U99_RS13195 (tssJ) | 2781080..2781562 | + | 483 | WP_006962078.1 | type VI secretion system lipoprotein TssJ |
| T6CP015906 | TssK | G3U99_RS13200 (tssK) | 2781583..2782914 | + | 1332 | WP_006962077.1 | type VI secretion system baseplate subunit TssK |
| T6CP015907 | TssL | G3U99_RS13205 (icmH) | 2782920..2784125 | + | 1206 | WP_031343073.1 | type IVB secretion system protein IcmH/DotU |
| T6CP015908 | TssM | G3U99_RS13210 (tssM) | 2784128..2787511 | + | 3384 | WP_021457565.1 | type VI secretion system membrane subunit TssM |
| G3U99_RS13215 | 2787514..2788260 | + | 747 | WP_165579640.1 | hypothetical protein | ||
| G3U99_RS13220 | 2788226..2791267 | - | 3042 | WP_096325389.1 | transporter substrate-binding domain-containing protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0355 |
N779_15250 (VtpR) | protein | QS regulatory pathway | Vibrio coralliilyticus OCN008 | chromosome (AVOO01000045) | 7579..8184 (-) | 536747482 | Unknown (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|