Detailed information of regulator

Summary

Regulator ID	REG0299
Regulator type	protein
Regulatory pathway (from literatures)	QS regulatory pathway
KEGG pathway (determined by BlastKOALA)	RNA degradation (map03018); Quorum sensing (map02024); Biofilm formation - Vibrio cholerae (map05111)
Related T6SS	T6SS01112 (Type i1)
Strain	Vibrio cholerae strain A1552
Replicon	chromosome
Sequence	Protein sequence (88 a.a.); Nucleotide sequence (264 bp)
Description	In the Δhfq mutant the expression of Hcp was increased at the earlier growth phase to the same extent as in the case of the ΔluxO mutant
Reference	[1] Ishikawa T, Rompikuntal PK, Lindmark B, et al. Quorum sensing regulation of the two hcp alleles in Vibrio cholerae O1 strains. PLoS One. 2009 Aug 24;4(8):e6734. doi: 10.1371/journal.pone.0006734. PMID: 19701456

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External database links

Locus tag (Gene)	VCA1552_RS00505 (hfq)
Coordinates (Strand)	92673..92936 (+)
NCBI ID	446974616
RefSeq	NZ_CP024867
Uniprot ID	A0A067BLS3_VIBMT, HFQ_VIBCH, A0A0X1L5K7_VIBCO, HFQ_VIBC3, D7HI07_VIBCL, A0A0K9UGM0_VIBCL, A0A0H3QAM2_VIBCL, HFQ_VIBCM, A0A085SA74_VIBCL, D0ID29_9VIBR
KEGG ID	vcr:VC395_0390, vcq:EN18_18670, vco:VC0395_A2758, vcm:VCM66_0331, vch:VC0347, vcz:VAB027_3485
KEGG pathway (determined by BlastKOALA)	map03018; map02024; map05111
PDB ID	-

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  Target

Target	Regulation (↓/↑)	Target sequence
VCA1552_00351 (HapR)	↑	-

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Pfam domain hit(s) of regulator

Domain	Pfam ID	E-value	Aligned region
Hfq	PF17209.5	2.4e-31	7..69

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Transmembrane helices

• Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-87	MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARPVSHHSGDRPASDRPAEKSEE

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Signal peptides

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9902	-	-

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  Protein sequence of regulator: 88 a.a.    .Download


  Nucleotide sequence of regulator: 264 bp    .Download