Detailed information of regulator
Summary
| Regulator ID | REG0118  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | Global regulator |
| KEGG pathway (determined by BlastKOALA) | Two-component system (map02020); Quorum sensing (map02024); Biofilm formation - Vibrio cholerae (map05111) |
| Related T6SS | T6SS00043 (Type i1) |
| Strain | Vibrio parahaemolyticus RIMD 2210633 |
| Replicon | chromosome |
| Sequence | Protein sequence (205 a.a.); Nucleotide sequence (615 bp) |
| Description | TfoX-mediated T6SS induction in V. parahaemolyticus requires co-regulation by OpaR. |
| Reference |
External database links
| Locus tag (Gene) | VP2516 (OpaR) |
| Coordinates (Strand) | 2653215..2653829 (+) |
| NCBI ID | 28899290 |
| RefSeq | NC_004603 |
| Uniprot ID | Q79YV4_VIBPA |
| KEGG ID | vpa:VP2516 |
| KEGG pathway (determined by BlastKOALA) | map02020; map02024; map05111 |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| T6SS1 | ↓ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| TetR_N | PF00440.25 | 1.8e-09 | 22..67 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-204 | MDSIAKRPRTRLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDEVLNHVVRQFSNFLSDNIDLDIHARENIANITNAMIELVSQDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLVQNMFIKAIERGEVCDQHDSEHLANLFHGICYSLFVQANRFKGEAELKELVSAYLDMLCIYNREH |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9920 | - | - |
Protein sequence of regulator: 205 a.a. .
>REG0118 NC_004603:2653215-2653829 [Vibrio parahaemolyticus RIMD 2210633]
MDSIAKRPRTRLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDEVLNHVVRQFSNFLS
DNIDLDIHARENIANITNAMIELVSQDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLVQNMFIKAIERGEVCDQHDSE
HLANLFHGICYSLFVQANRFKGEAELKELVSAYLDMLCIYNREH*
MDSIAKRPRTRLSPLKRKQQLMEIALEVFARRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDEVLNHVVRQFSNFLS
DNIDLDIHARENIANITNAMIELVSQDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLVQNMFIKAIERGEVCDQHDSE
HLANLFHGICYSLFVQANRFKGEAELKELVSAYLDMLCIYNREH*
Nucleotide sequence of regulator: 615 bp .
>REG0118 NC_004603:2653215-2653829 [Vibrio parahaemolyticus RIMD 2210633]
ATGGACTCAATTGCAAAGAGACCTAGAACTAGGCTTTCTCCTCTTAAACGTAAGCAACAACTCATGGAAATCGCGTTAGA
AGTATTTGCACGCCGTGGTATTGGCCGTGGTGGTCACGCAGATATTGCTGAAATTGCGCAAGTGTCTGTTGCAACCGTTT
TTAACTACTTCCCAACTCGCGAAGATTTGGTTGATGAAGTTCTCAACCATGTTGTCCGTCAGTTCTCGAATTTCCTTTCG
GACAATATCGACCTAGACATACACGCTCGTGAAAACATCGCAAACATCACCAATGCGATGATCGAGCTTGTAAGCCAAGA
TTGTCACTGGCTGAAAGTTTGGTTCGAGTGGAGCGCATCAACTCGTGATGAAGTTTGGCCTCTATTTGTGTCTACCAACC
GCACTAACCAATTATTGGTTCAAAACATGTTCATTAAAGCGATTGAACGCGGTGAAGTGTGTGATCAACACGATTCAGAA
CACTTGGCAAACCTATTCCACGGTATTTGTTACTCGCTGTTCGTACAAGCAAACCGCTTCAAAGGTGAAGCCGAGTTGAA
AGAGCTCGTGAGCGCTTACCTAGATATGCTTTGCATCTACAATCGCGAACACTAA
ATGGACTCAATTGCAAAGAGACCTAGAACTAGGCTTTCTCCTCTTAAACGTAAGCAACAACTCATGGAAATCGCGTTAGA
AGTATTTGCACGCCGTGGTATTGGCCGTGGTGGTCACGCAGATATTGCTGAAATTGCGCAAGTGTCTGTTGCAACCGTTT
TTAACTACTTCCCAACTCGCGAAGATTTGGTTGATGAAGTTCTCAACCATGTTGTCCGTCAGTTCTCGAATTTCCTTTCG
GACAATATCGACCTAGACATACACGCTCGTGAAAACATCGCAAACATCACCAATGCGATGATCGAGCTTGTAAGCCAAGA
TTGTCACTGGCTGAAAGTTTGGTTCGAGTGGAGCGCATCAACTCGTGATGAAGTTTGGCCTCTATTTGTGTCTACCAACC
GCACTAACCAATTATTGGTTCAAAACATGTTCATTAAAGCGATTGAACGCGGTGAAGTGTGTGATCAACACGATTCAGAA
CACTTGGCAAACCTATTCCACGGTATTTGTTACTCGCTGTTCGTACAAGCAAACCGCTTCAAAGGTGAAGCCGAGTTGAA
AGAGCTCGTGAGCGCTTACCTAGATATGCTTTGCATCTACAATCGCGAACACTAA