Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01028  |
| T6SS type | Type i1 |
| Strain | Vibrio fluvialis 85003 |
| Replicon (GenBank) | chromosome (KY319183) |
| Location | 2525..21696 |
| Function | anti-bacterial |
| Comment | V.fluvialis 85003 can secrete hcp and shows VflT6SS2-dependent competition with E.coli strain MG1655. |
| References | [1] Huang Y, Du P, Zhao M, Liu W, Du Y, Diao B, Li J, Kan B, Liang W. et al (2017) Functional Characterization and Conditional Regulation of the Type VI Secretion System in Vibrio fluvialis.. Front Microbiol. 0.7. [PudMed:28424671] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| Locus_01 | 1..444 | + | 444 | 1185549741 | AsnC family transcriptional regulator | ||
| Locus_02 | 868..1152 | + | 285 | 1185549742 | uropathogenic-specific protein | ||
| Locus_03 | 1097..2143 | + | 1047 | 1185549743 | hypothetical protein | ||
| T6CP013332 | TssB | Locus_04 (tssB2) | 2525..3034 | + | 510 | 1185549744 | putative protein ImpB |
| T6CP013333 | TssC | Locus_05 (tssC2) | 3081..4556 | + | 1476 | 1185549745 | putative protein ImpC |
| T6CP013334 | TssE | Locus_06 (tssE2) | 4559..4996 | + | 438 | 1185549746 | ImpF-like protein |
| T6CP013335 | TssF | Locus_07 (tssF2) | 5002..6771 | + | 1770 | 1185549747 | ImpG/VasA |
| T6CP013336 | TssG | Locus_08 (tssG2) | 6735..7751 | + | 1017 | 1185549748 | putative protein ImpH/VasB |
| Locus_09 (tagH2) | 7755..9233 | + | 1479 | 1185549749 | putative protein ImpI/VasC | ||
| T6CP013337 | TssJ | Locus_10 (tssJ2) | 9236..9712 | + | 477 | 1185549750 | type VI secretion lipoprotein VasD |
| T6CP013338 | TssK | Locus_11 (tssK2) | 9719..11053 | + | 1335 | 1185549751 | putative protein ImpJ/VasE |
| T6CP013339 | TssL | Locus_12 (tssL2) | 11056..11829 | + | 774 | 1185549752 | outer membrane protein ImpK/VasF |
| T6CP013340 | TssH | Locus_13 (tssH2) | 11856..14468 | + | 2613 | 1185549753 | ClpB protein |
| Locus_14 (vasH) | 14471..16066 | + | 1596 | 1185549754 | sigma-54 dependent transcriptional regulator | ||
| Locus_15 (vasI) | 16063..16722 | + | 660 | 1185549755 | type VI secretion protein VasI | ||
| T6CP013341 | TssA | Locus_16 (tssA2) | 16732..18132 | + | 1401 | 1185549756 | putative protein ImpA |
| T6CP013342 | TssM | Locus_17 (tssM2) | 18151..21696 | + | 3546 | 1185549757 | IcmF-related protein |
| Locus_18 (vasL) | 21749..23026 | + | 1278 | 1185549758 | type VI secretion-related protein VasL | ||
| Locus_19 (tssI2) | 23213..26251 | + | 3039 | 1185549759 | VgrG protein | ||
| Locus_20 (tsiI2) | 26248..26631 | + | 384 | 1185549760 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0373 |
hapR | protein | QS regulatory pathway | Vibrio fluvialis 85003 | chromosome (KY319184) | - | - | vgrG (↓) |
| REG0374 |
ihfA | protein | QS regulatory pathway | Vibrio fluvialis 85003 | chromosome (KY319184) | - | - | vgrG (↓) |
| REG0375 |
ihfB | protein | QS regulatory pathway | Vibrio fluvialis 85003 | chromosome (KY319184) | - | - | vgrG (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF18629 |
tssD2_a | - | IMU17309 |
Vibrio fluvialis strain 85003 | chromosome (KY319185) | 1820..2338 (+) | ARK19412.1 |
| EFF18630 |
tssD2_b | - | IMU17310 |
Vibrio fluvialis strain 85003 | chromosome (KY319186) | 2484..3002 (+) | ARK19415.1 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU17309 |
tssI2_a | EFF18629 |
Vibrio fluvialis strain 85003 | chromosome (KY319185) | 2490..4556 (+) | ARK19413.1 |
| IMU17310 |
tssI2_b | EFF18630 |
Vibrio fluvialis strain 85003 | chromosome (KY319186) | 3154..5250 (+) | ARK19416.1 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|