Detailed information of regulator
Summary
| Regulator ID | REG0180  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | Global regulator |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00208  (Type i1); T6SS00487 (Type Unknown) |
| Strain | Vibrio cholerae O395 |
| Replicon | chromosome |
| Sequence | Protein sequence (95 a.a.); Nucleotide sequence (285 bp) |
| Description | - |
| Reference |
External database links
| Locus tag (Gene) | VC0395_RS17530 (TsrA) |
| Coordinates (Strand) | 2598392..2598676 (-) |
| NCBI ID | 445982516 |
| RefSeq | NC_009457 |
| Uniprot ID | Q9KVR9_VIBCH, A0A0X1L4V1_VIBCO, A0A0H3AMG6_VIBC3, D7HGY5_VIBCL, A0A0K9UN17_VIBCL, A0A0H3Q5F4_VIBCL, C3LPR2_VIBCM, A0A1X1LD77_VIBCL |
| KEGG ID | vch:VC0070, vcm:VCM66_0070, vcx:VAA049_62, vcz:VAB027_62, vcq:EN18_17180, vco:VC0395_A2444 |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| T6SS Transciption | ↑ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-94 | MSLTTYEMARILEQLDESPEKVMYGKLLNELGNQSSERIRSAAKQVPLTVLRDLVYQFQQVIESRKGEQVETMAKELAKQGISAEELLNYLQKR |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9967 | - | - |
Protein sequence of regulator: 95 a.a. .
>REG0180 NC_009457:c2598676-2598392 [Vibrio cholerae O395]
MSLTTYEMARILEQLDESPEKVMYGKLLNELGNQSSERIRSAAKQVPLTVLRDLVYQFQQVIESRKGEQVETMAKELAKQ
GISAEELLNYLQKR*
MSLTTYEMARILEQLDESPEKVMYGKLLNELGNQSSERIRSAAKQVPLTVLRDLVYQFQQVIESRKGEQVETMAKELAKQ
GISAEELLNYLQKR*
Nucleotide sequence of regulator: 285 bp .
>REG0180 NC_009457:c2598676-2598392 [Vibrio cholerae O395]
ATGTCTCTAACCACCTATGAAATGGCTCGCATTCTGGAACAACTTGATGAATCTCCAGAAAAGGTGATGTATGGCAAGTT
GCTTAATGAATTAGGCAATCAAAGCAGTGAACGTATTCGCAGTGCGGCCAAGCAAGTGCCACTGACCGTGCTACGCGATC
TGGTTTACCAGTTCCAGCAAGTGATCGAGTCACGCAAGGGCGAGCAAGTCGAAACCATGGCTAAAGAACTCGCTAAACAG
GGCATCTCTGCGGAAGAGCTTCTGAATTACTTACAAAAACGCTAA
ATGTCTCTAACCACCTATGAAATGGCTCGCATTCTGGAACAACTTGATGAATCTCCAGAAAAGGTGATGTATGGCAAGTT
GCTTAATGAATTAGGCAATCAAAGCAGTGAACGTATTCGCAGTGCGGCCAAGCAAGTGCCACTGACCGTGCTACGCGATC
TGGTTTACCAGTTCCAGCAAGTGATCGAGTCACGCAAGGGCGAGCAAGTCGAAACCATGGCTAAAGAACTCGCTAAACAG
GGCATCTCTGCGGAAGAGCTTCTGAATTACTTACAAAAACGCTAA