Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


T6SS ID T6SS01286 experimental
T6SS type Type Unknown
Strain Vibrio fischeri EBS004
Replicon (GenBank) (-)
Location -
Function anti-bacterial
Comment When incubated with either wild-type FQ-A001 or the vasA_1 mutant, ES114 was killed by 5 h and not visibly de- tected at 15 h. In contrast, when incubated with the vasA_2 mutant, ES114 was able to grow after 5 h and was visibly detectable in the mixed colony after 15 h. When vasA_2 was complemented in trans using an isopropyl-D-thio- galactopyranoside (IPTG)-inducible expression vector, killing was restored in an IPTG-dependent manner show that FQ-A001 uses T6SS2 to kill ES114 and T6SS2 encodes the necessary components to assemble a sheath, which is dependent on the baseplate component VasA_2
[1] Speare L, Cecere AG, Guckes KR, Smith S, Wollenberg MS, Mandel MJ, Miyashiro T, Septer AN. et al (2018) Bacterial symbionts use a type VI secretion system to eliminate competitors in their natural host.. Proc Natl Acad Sci U S A. 115(36):E8528-E8537. [PudMed:30127013]
experimental Experimental investigation has been performed.