Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS01253 experimental
T6SS type Type i5
Strain Vibrio parahaemolyticus strain 12-009A/1335
Replicon (RefSeq) chromosome (NZ_MYFF01000494)
Location 7384..30649
Function anti-bacterial
Comment T6SS1 can secrete VGRG and the activity was required for the observed bactericidal activity at 30°C
References
[1] Li P, Kinch LN, Ray A, Dalia AB, Cong Q, Nunan LM, Camilli A, Grishin NV, Salomon D, Orth K. et al (2017) Acute Hepatopancreatic Necrosis Disease-Causing Vibrio parahaemolyticus Strains Maintain an Antibacterial Type VI Secretion System with Versatile Effector Repertoires.. Appl Environ Microbiol. 83(13). [PudMed:28432099]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentTagFTagHTssATssBTssCTssDTssETssFTssGTssHTssITssJTssKTssLTssM
Number111121111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
B5C29_RS20050 5007..6140 - 1134 1189147650 exonuclease SbcCD subunit D
B5C29_RS20055 6237..7079 - 843 1189147651 transhydrogenase beta subunit
B5C29_RS20060 7080..7370 - 291 491641481 PAAR domain-containing protein
T6CP015696 TssI B5C29_RS20065 (tssI) 7384..9219 - 1836 646568991 type VI secretion system tip protein VgrG
T6CP015697 TssD B5C29_RS20070 9277..9756 - 480 491518336 type VI secretion system tube protein Hcp
T6CP015698 TssH B5C29_RS20075 (tssH) 9962..12529 - 2568 686278494 type VI secretion system ATPase TssH
T6CP015699 TssG B5C29_RS20080 (tssG) 12540..13505 - 966 686278493 type VI secretion system baseplate subunit TssG
T6CP015700 TssF B5C29_RS20085 (tssF) 13502..15325 - 1824 646403521 type VI secretion system baseplate subunit TssF
T6CP015701 TssE B5C29_RS20090 (tssE) 15322..15786 - 465 505126202 type VI secretion system baseplate subunit TssE
B5C29_RS20095 15795..16592 - 798 686278492 protein of avirulence locus
T6CP015702 TssC B5C29_RS20100 (tssC) 16603..18114 - 1512 686278491 type VI secretion system contractile sheath large subunit
T6CP015703 TssC B5C29_RS20105 (tssC) 18170..19663 - 1494 491606251 type VI secretion system contractile sheath large subunit
T6CP015704 TssB B5C29_RS20110 (tssB) 19663..20193 - 531 491606249 type VI secretion system contractile sheath small subunit
T6CP015705 TssA B5C29_RS20115 (tssA) 20209..21330 - 1122 659012108 type VI secretion system protein TssA
B5C29_RS20120 21327..22115 - 789 491606245 serine/threonine-protein phosphatase
T6CP015706 TagF B5C29_RS20125 (tagF) 22126..22821 - 696 686278490 type VI secretion system-associated protein TagF
T6CP015707 TssM B5C29_RS20130 (tssM) 22803..26321 - 3519 686278489 type VI secretion system membrane subunit TssM
T6CP015708 TssL B5C29_RS20135 (tssL) 26337..27629 - 1293 516016889 type VI secretion system protein TssL, long form
T6CP015709 TssK B5C29_RS20140 (tssK) 27641..28966 - 1326 516016888 type VI secretion system baseplate subunit TssK
T6CP015710 TssJ B5C29_RS20145 (tssJ) 28988..29443 - 456 491606235 type VI secretion system lipoprotein TssJ
T6CP015711 TagH B5C29_RS20150 (tagH) 29453..30649 - 1197 491606233 type VI secretion system-associated FHA domain protein TagH
B5C29_RS20160 30972..33113 + 2142 686278487 serine/threonine protein kinase
B5C29_RS20165 33225..34760 + 1536 686278486 response regulator
B5C29_RS20170 34763..35098 + 336 686278485 hypothetical protein
B5C29_RS27745 35134..35325 + 192 639576797 hypothetical protein
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector