Detailed information of regulator
Summary
Regulator ID | REG0320 |
Regulator type | protein |
Regulatory pathway (from literatures) | Transcription regulator |
KEGG pathway (determined by BlastKOALA) | - |
Related T6SS | T6SS00002 (Type i1) |
Strain | Vibrio cholerae O1 biovar El Tor str. N16961 |
Replicon | chromosome |
Sequence | Protein sequence (81 a.a.); Nucleotide sequence (243 bp) |
Description | β-galactosidase activity assay show VCA0122 controls Hcp expression at the transcriptional level |
Reference |
External database links
Locus tag (Gene) | VC_A0122 |
Coordinates (Strand) | 137379..137621 (+) |
NCBI ID | 9657509 |
RefSeq | NC_002506 |
Uniprot ID | Q9KN43_VIBCH |
KEGG ID | vch:VCA0122 |
KEGG pathway (determined by BlastKOALA) | - |
PDB ID | - |
Target
Target | Regulation (↓/↑) | Target sequence |
---|---|---|
hcp-2 expression | ↓ | - |
Pfam domain hit(s) of regulator
Domain | Pfam ID | E-value | Aligned region |
---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
Prediction | Region | Sequence |
---|---|---|
Outside | 1-80 | MIGARDCSVIRVNPGAKQGKVDKKLALSLPLTATQYFQRTIFNEPFSSNLRWPHIECYRRKKEQGKQHGKVTVSIKGGWP |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction | Probability | Cleavage site | Signal peptide sequence |
---|---|---|---|
Other | 0.9767 | - | - |
Protein sequence of regulator: 81 a.a. .
>REG0320 NC_002506:137379-137621 [Vibrio cholerae O1 biovar El Tor str. N16961]
MIGARDCSVIRVNPGAKQGKVDKKLALSLPLTATQYFQRTIFNEPFSSNLRWPHIECYRRKKEQGKQHGKVTVSIKGGWP
*
MIGARDCSVIRVNPGAKQGKVDKKLALSLPLTATQYFQRTIFNEPFSSNLRWPHIECYRRKKEQGKQHGKVTVSIKGGWP
*
Nucleotide sequence of regulator: 243 bp .
>REG0320 NC_002506:137379-137621 [Vibrio cholerae O1 biovar El Tor str. N16961]
TTGATTGGGGCAAGGGATTGCTCAGTGATAAGAGTTAACCCTGGTGCGAAACAGGGAAAAGTAGACAAAAAGCTGGCATT
GAGTTTGCCATTGACTGCCACACAATATTTTCAACGCACCATTTTCAACGAACCATTTTCATCGAACTTAAGATGGCCAC
ATATCGAGTGCTATCGTCGAAAAAAAGAACAAGGAAAACAGCATGGCAAGGTTACAGTTTCAATTAAAGGTGGATGGCCT
TGA
TTGATTGGGGCAAGGGATTGCTCAGTGATAAGAGTTAACCCTGGTGCGAAACAGGGAAAAGTAGACAAAAAGCTGGCATT
GAGTTTGCCATTGACTGCCACACAATATTTTCAACGCACCATTTTCAACGAACCATTTTCATCGAACTTAAGATGGCCAC
ATATCGAGTGCTATCGTCGAAAAAAAGAACAAGGAAAACAGCATGGCAAGGTTACAGTTTCAATTAAAGGTGGATGGCCT
TGA