Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01277  |
| T6SS type | Type i1 |
| Strain | Aliivibrio fischeri strain FQ-A001 |
| Replicon (RefSeq) | chromosome (NZ_SJSX01000002) |
| Location | 747470..766109 |
| Function | anti-bacterial |
| Comment | T6SS is a functional antibacterial system |
| References | [1] Guckes KR, Cecere AG, Wasilko NP, Williams AL, Bultman KM, Mandel MJ, Miyashiro T. et al (2019) Incompatibility of Vibrio fischeri Strains during Symbiosis Establishment Depends on Two Functionally Redundant hcp Genes.. J Bacteriol. 201(19). [PudMed:31331977] [2] Speare L, Cecere AG, Guckes KR, Smith S, Wollenberg MS, Mandel MJ, Miyashiro T, Septer AN. et al (2018) Bacterial symbionts use a type VI secretion system to eliminate competitors in their natural host.. Proc Natl Acad Sci U S A. 115(36):E8528-E8537. [PudMed:30127013] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagH | TssA | TssB | TssC | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| VFFQA001_RS05415 | 743013..743762 | + | 750 | 1027729110 | DUF481 domain-containing protein | ||
| VFFQA001_RS05420 | 743950..745845 | + | 1896 | 1597592720 | diguanylate cyclase | ||
| VFFQA001_RS05425 | 745846..746805 | - | 960 | 1597592721 | serine/threonine protein kinase | ||
| VFFQA001_RS05430 | 746802..747473 | - | 672 | 491561111 | serine/threonine-protein phosphatase | ||
| T6CP015871 | TssM | VFFQA001_RS05435 (tssM) | 747470..750991 | - | 3522 | 1597592722 | type VI secretion system membrane subunit TssM |
| T6CP015872 | TssL | VFFQA001_RS05440 | 751002..751835 | - | 834 | 491561116 | type IVB secretion system protein IcmH/DotU |
| T6CP015873 | TssK | VFFQA001_RS05445 (tssK) | 751837..753159 | - | 1323 | 1597592723 | type VI secretion system baseplate subunit TssK |
| T6CP015874 | TssJ | VFFQA001_RS05450 (tssJ) | 753171..753662 | - | 492 | 499580846 | type VI secretion system lipoprotein TssJ |
| T6CP015875 | TagH | VFFQA001_RS05455 (tagH) | 753699..755009 | - | 1311 | 1597592724 | type VI secretion system-associated FHA domain protein TagH |
| VFFQA001_RS05465 | 755144..756712 | - | 1569 | 1597592725 | sigma-54-dependent Fis family transcriptional regulator |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0124 | VFFQA001_02105 (rpoN) | protein | Global regulator | Aliivibrio fischeri strain FQ-A001 | chromosome (NZ_SJSX01000002) | 62995..64464 (-) | 501526930 | hcp1/hcp transcript (↓) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||