Detailed information of immunity protein


Summary

Immunity protein ID IMU00351 experimental
Cognate effector EFF01530 experimental
Related T6SS (Type) T6SS01262 experimental (Type i1)
Strain Vibrio parahaemolyticus strain 12-297/B C4271
Replicon chromosome
Sequence Protein sequence (328 a.a.); Nucleotide sequence (984 bp)
Description V12_14460 contains a domain of unknown function 1911 (DUF1911),which are often accompanied by DUF1910, provide immunity against PoNe-containing DNase toxins
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) B5C30_RS14460
Coordinates (Strand) 17970..18953 (-)
NCBI ID 639578399
RefSeq NZ_MYFG01000470
Uniprot ID UPI00040290AE
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
DUF1911 PF08929.12 2.8e-26 159..254
DUF1910 PF08928.12 1.3e-08 13..123
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-327 VNTNEMKFTQSRRDPLLELGVYEEVNNYFSKDKTPRFEKMKDPTKSLTNRSRISWSITLNCFEHAILSYSGGQAMESVLDLTEVALKALERHKNDFPHKSYLFWEPDSFQFLLWCLSFVALTGKTEYLSTITRMYGTSPEVSGEACMAQLFRLFNVHGIPDSTEEALVFPDSYQHLYNAIKTGPLEPSKKEREESVKTYLRGWYKGMKDCYWHNRHKARFPTFFGYWALEAAMITLLFDLDDTGYNHLPYYPKDWVAEARKQGFDKLILKANLPSIQVAFPETMCPMTGEWQSNLSSEVLSLKEGEIMPGPLQDENETSYFWVLQEA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9858 - -


  Protein sequence: 328 a.a.    .

>IMU00351 NZ_MYFG01000470:c18953-17970 [Vibrio parahaemolyticus]
VNTNEMKFTQSRRDPLLELGVYEEVNNYFSKDKTPRFEKMKDPTKSLTNRSRISWSITLNCFEHAILSYSGGQAMESVLD
LTEVALKALERHKNDFPHKSYLFWEPDSFQFLLWCLSFVALTGKTEYLSTITRMYGTSPEVSGEACMAQLFRLFNVHGIP
DSTEEALVFPDSYQHLYNAIKTGPLEPSKKEREESVKTYLRGWYKGMKDCYWHNRHKARFPTFFGYWALEAAMITLLFDL
DDTGYNHLPYYPKDWVAEARKQGFDKLILKANLPSIQVAFPETMCPMTGEWQSNLSSEVLSLKEGEIMPGPLQDENETSY
FWVLQEA*

  Nucleotide sequence: 984 bp    .

>IMU00351 NZ_MYFG01000470:c18953-17970 [Vibrio parahaemolyticus]
GTGAATACAAATGAAATGAAGTTTACTCAATCTAGACGAGACCCATTACTTGAGTTAGGTGTGTATGAGGAAGTCAATAA
TTATTTCAGTAAAGATAAGACCCCTCGTTTTGAAAAGATGAAAGATCCAACCAAAAGTCTTACAAATCGATCTAGGATAA
GCTGGAGTATAACGCTCAATTGTTTTGAGCATGCCATATTGAGTTACTCTGGCGGACAAGCGATGGAAAGCGTATTGGAT
CTCACCGAGGTTGCATTAAAAGCATTAGAAAGACACAAAAATGATTTTCCCCATAAATCCTACTTGTTTTGGGAACCTGA
CTCTTTCCAGTTCTTATTATGGTGTTTAAGTTTTGTTGCACTAACTGGAAAAACAGAGTACCTATCAACTATCACTCGCA
TGTATGGAACGTCACCGGAAGTGAGTGGTGAGGCTTGCATGGCTCAGTTGTTCCGCTTGTTTAATGTTCATGGTATTCCA
GATAGCACTGAAGAAGCTCTGGTCTTTCCCGACAGCTACCAGCATTTGTATAACGCGATAAAAACGGGTCCACTGGAGCC
GAGTAAAAAAGAGCGTGAAGAAAGCGTTAAAACTTACCTTCGCGGTTGGTATAAAGGCATGAAAGATTGTTATTGGCATA
ATAGACACAAAGCACGTTTTCCAACGTTTTTTGGTTATTGGGCATTGGAAGCCGCCATGATCACTTTGCTATTTGATTTA
GATGATACTGGTTACAATCATTTGCCTTATTACCCGAAGGATTGGGTAGCAGAAGCACGTAAACAAGGTTTTGATAAGTT
GATACTGAAGGCTAATTTACCGTCTATCCAAGTCGCATTTCCTGAAACAATGTGCCCAATGACAGGGGAATGGCAATCTA
ACCTTTCTTCTGAGGTGCTTTCTCTCAAAGAAGGAGAAATAATGCCGGGTCCACTACAAGATGAAAATGAAACCTCTTAC
TTTTGGGTTTTACAGGAAGCTTGA