Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01281  |
| T6SS type | Type i1 |
| Strain | Vibrio coralliilyticus OCN008 |
| Replicon (RefSeq) | chromosome II (NZ_CP048694) |
| Location | 1627613..1656598 |
| Function | anti-bacterial |
| Comment | V. coralliilyticus has a functional which showed effective at killing V.cholerae and required for resistance to T6SS-mediated killing by V.cholerae |
| References | [1] Guillemette R, Ushijima B, Jalan M, H |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagH | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| G3U99_RS23790 | 1624691..1625836 | + | 1146 | WP_031342768.1 | hypothetical protein | ||
| G3U99_RS23795 | 1625989..1627626 | - | 1638 | WP_021456527.1 | sigma-54 dependent transcriptional regulator | ||
| T6CP015909 | TssH | G3U99_RS23800 (tssH) | 1627613..1630285 | - | 2673 | WP_165579905.1 | type VI secretion system ATPase TssH |
| T6CP015910 | TssD | G3U99_RS23805 | 1630748..1631266 | + | 519 | WP_006961152.1 | Hcp family type VI secretion system effector |
| T6CP015911 | TssI | G3U99_RS23810 (tssI) | 1631338..1633416 | + | 2079 | WP_040121702.1 | type VI secretion system tip protein VgrG |
| G3U99_RS23815 | 1633416..1633901 | + | 486 | WP_021457337.1 | hypothetical protein | ||
| G3U99_RS23820 | 1633921..1635240 | + | 1320 | WP_021457338.1 | hypothetical protein | ||
| G3U99_RS23825 | 1635221..1636204 | + | 984 | WP_165579906.1 | DUF2169 domain-containing protein | ||
| G3U99_RS23830 | 1636201..1637154 | + | 954 | WP_021457341.1 | hypothetical protein | ||
| G3U99_RS23835 | 1637366..1639360 | + | 1995 | WP_021457342.1 | protein kinase | ||
| T6CP015912 | TssA | G3U99_RS23840 (tssA) | 1639364..1640929 | + | 1566 | WP_165579907.1 | type VI secretion system protein TssA |
| T6CP015913 | TssB | G3U99_RS23845 (tssB) | 1640957..1641466 | + | 510 | WP_006961144.1 | type VI secretion system contractile sheath small subunit |
| T6CP015914 | TssC | G3U99_RS23850 (tssC) | 1641476..1642951 | + | 1476 | WP_006961143.1 | type VI secretion system contractile sheath large subunit |
| T6CP015915 | TssE | G3U99_RS23855 (tssE) | 1643015..1643425 | + | 411 | WP_019277706.1 | type VI secretion system baseplate subunit TssE |
| T6CP015916 | TssF | G3U99_RS23860 (tssF) | 1643444..1645192 | + | 1749 | WP_006961141.1 | type VI secretion system baseplate subunit TssF |
| T6CP015917 | TssG | G3U99_RS23865 (tssG) | 1645189..1646187 | + | 999 | WP_165579908.1 | type VI secretion system baseplate subunit TssG |
| G3U99_RS23870 | 1646256..1646708 | - | 453 | WP_019277704.1 | Lrp/AsnC family transcriptional regulator | ||
| T6CP015918 | TssM | G3U99_RS23875 (tssM) | 1646746..1650141 | - | 3396 | WP_165579909.1 | type VI secretion system membrane subunit TssM |
| T6CP015919 | TssA | G3U99_RS23880 | 1650144..1651451 | - | 1308 | WP_165579910.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| G3U99_RS23885 | 1651980..1652582 | + | 603 | WP_006961135.1 | hypothetical protein | ||
| T6CP015920 | TagH | G3U99_RS23890 (tagH) | 1652595..1653980 | + | 1386 | WP_021457349.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP015921 | TssJ | G3U99_RS23895 (tssJ) | 1653973..1654473 | + | 501 | WP_019277701.1 | type VI secretion system lipoprotein TssJ |
| T6CP015922 | TssK | G3U99_RS23900 (tssK) | 1654485..1655810 | + | 1326 | WP_021457350.1 | type VI secretion system baseplate subunit TssK |
| T6CP015923 | TssL | G3U99_RS23905 (icmH) | 1655807..1656598 | + | 792 | WP_021457351.1 | type IVB secretion system protein IcmH/DotU |
| G3U99_RS23910 | 1657069..1660116 | + | 3048 | WP_021457352.1 | beta-galactosidase | ||
| G3U99_RS23915 (melB) | 1660197..1661549 | + | 1353 | WP_021457353.1 | melibiose:sodium transporter MelB |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0355 |
N779_15250 (VtpR) | protein | QS regulatory pathway | Vibrio coralliilyticus OCN008 | chromosome (AVOO01000045) | 7579..8184 (-) | 536747482 | Unknown (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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