Detailed information of regulator


Summary

Regulator ID REG0117 experimental
Regulator type protein
Regulatory pathway (from literatures) c-di-GMP regulatory pathway
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00043 experimental (Type i1)
Strain Vibrio parahaemolyticus RIMD 2210633
Replicon chromosome
Sequence Protein sequence (457 a.a.); Nucleotide sequence (1371 bp)
Description c-di-GMP-producing diguanylate cyclase.
Reference

External database links

Locus tag (Gene) VPA0739 (vdcA)
Coordinates (Strand) 772439..773809 (+)
NCBI ID 28900594
RefSeq NC_004605
Uniprot ID Q87I67_VIBPA
KEGG ID vpa:VPA0739
KEGG pathway (determined by BlastKOALA) -
PDB ID -

  Target
Target Regulation (↓/↑) Target sequence
VP1028 (TfoY) -

Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
GGDEF PF00990.23 2.4e-33 307..453

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-6 MTFKSI
Transmembrane helix 7-29 ALSFFVATLLFATSTMMIGAVLI
Outside 30-265 SYEVKQFNTYANNLAKIKQKVILMGLLTEAKLEQYKGLSVDEVEAQTEFSFQDAIYSLSPYEKLNYVEAVARKSLHQAEAYLSNAFNRQNAIMYFRSYTGSKLILERPIKALEGVKATFDVDWCKSNYSCVLAAWKEQLTDRVLFSLPFKTTYSDDMAISIMSPVYFQGELVGEFSEQLYLSSLYNEGKAVDVQISNGNKQMVIYFSGYPWPSFAYTQSFVADNNNLIVYMYPFSK
Transmembrane helix 266-285 VMVDYSFLFVIFFLATLAYY
Inside 286-456 NKAHESKESKLRLATALTNVTKDDLTGLLNRRVFKDSEFKRRLKTAPYSVIAIDGDRIKRINDRYGHHVGDEVIEIIADAMRKVFRTSDYLVRTGGDEFIAILPGCSISQSSMLAKKLRSFVKDNRLKTLDIEVSVSTGVAANESHESLQDVIVRADEDLYEMKKRRQHSQ



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8201 - -



  Protein sequence of regulator: 457 a.a.    .

>REG0117 NC_004605:772439-773809 [Vibrio parahaemolyticus RIMD 2210633]
MTFKSIALSFFVATLLFATSTMMIGAVLISYEVKQFNTYANNLAKIKQKVILMGLLTEAKLEQYKGLSVDEVEAQTEFSF
QDAIYSLSPYEKLNYVEAVARKSLHQAEAYLSNAFNRQNAIMYFRSYTGSKLILERPIKALEGVKATFDVDWCKSNYSCV
LAAWKEQLTDRVLFSLPFKTTYSDDMAISIMSPVYFQGELVGEFSEQLYLSSLYNEGKAVDVQISNGNKQMVIYFSGYPW
PSFAYTQSFVADNNNLIVYMYPFSKVMVDYSFLFVIFFLATLAYYNKAHESKESKLRLATALTNVTKDDLTGLLNRRVFK
DSEFKRRLKTAPYSVIAIDGDRIKRINDRYGHHVGDEVIEIIADAMRKVFRTSDYLVRTGGDEFIAILPGCSISQSSMLA
KKLRSFVKDNRLKTLDIEVSVSTGVAANESHESLQDVIVRADEDLYEMKKRRQHSQ*

  Nucleotide sequence of regulator: 1371 bp    .

>REG0117 NC_004605:772439-773809 [Vibrio parahaemolyticus RIMD 2210633]
ATGACATTTAAAAGCATCGCGCTGTCTTTCTTTGTGGCGACGTTACTGTTTGCGACTTCAACAATGATGATAGGCGCTGT
GTTGATTTCTTATGAAGTAAAGCAGTTCAACACCTACGCAAATAACCTAGCCAAAATAAAGCAAAAAGTCATTTTAATGG
GGCTGCTGACGGAAGCGAAGCTTGAACAATACAAAGGCTTGAGCGTGGATGAAGTAGAAGCTCAAACTGAGTTCAGCTTC
CAAGACGCGATTTACTCGCTGTCACCGTACGAAAAGCTGAATTACGTTGAAGCCGTCGCACGCAAATCGCTGCATCAAGC
CGAAGCGTATTTATCGAATGCGTTTAATCGACAAAATGCCATTATGTACTTTCGCTCTTATACTGGGAGCAAGTTGATTT
TAGAGCGACCAATCAAAGCGTTAGAAGGTGTGAAGGCCACATTCGATGTCGATTGGTGCAAGAGCAACTACTCTTGCGTT
CTGGCTGCGTGGAAAGAACAACTGACTGATCGCGTGTTGTTTTCTCTGCCGTTTAAAACCACCTACTCGGATGACATGGC
AATAAGCATCATGAGCCCGGTTTATTTCCAAGGTGAGCTAGTCGGCGAGTTTTCAGAACAGCTCTATCTTTCATCACTTT
ATAACGAAGGGAAAGCCGTCGACGTACAGATCTCCAATGGTAACAAGCAAATGGTGATCTATTTTTCGGGTTATCCGTGG
CCATCGTTCGCGTACACCCAATCTTTTGTGGCAGACAACAACAACTTGATTGTCTACATGTACCCGTTTAGTAAAGTGAT
GGTGGATTACAGCTTTCTGTTTGTTATTTTCTTTTTGGCAACCTTGGCGTATTACAACAAAGCGCATGAATCCAAAGAGA
GCAAACTTCGTCTGGCGACGGCACTGACGAATGTGACAAAAGACGATTTAACCGGGTTACTTAACCGCAGAGTCTTTAAA
GATAGCGAATTCAAACGCCGCTTGAAAACGGCCCCTTATTCCGTCATTGCCATTGATGGCGACAGGATCAAGCGAATCAA
TGATCGCTATGGTCATCACGTTGGGGACGAGGTTATCGAGATCATTGCCGATGCGATGCGTAAAGTGTTCAGAACCAGCG
ATTATCTCGTCCGAACTGGGGGCGATGAGTTTATCGCAATCTTGCCGGGGTGCAGCATCAGTCAGTCTTCGATGTTGGCG
AAAAAGTTACGTAGCTTTGTCAAAGACAACCGACTTAAAACGTTAGACATTGAAGTCAGCGTAAGCACTGGCGTTGCGGC
AAACGAATCACACGAATCACTGCAAGATGTTATCGTTCGAGCAGATGAAGATCTCTATGAGATGAAAAAACGCAGACAAC
ACTCACAGTAA