Detailed information of immunity protein
Summary
| Immunity protein ID | IMU00172  |
| Cognate effector | EFF00005 |
| Related T6SS (Type) | T6SS00002 (Type i1) |
| Strain | Vibrio cholerae O1 biovar El Tor str. N16961 |
| Replicon | chromosome |
| Sequence | Protein sequence (123 a.a.); Nucleotide sequence (369 bp) |
| Description | TsiV3 |
| Reference | - |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | VCA0124 (TsiV3) |
| Coordinates (Strand) | 140631..140999 (+) |
| NCBI ID | 15600895 |
| RefSeq | NC_002506 |
| Uniprot ID | TSIV3_VIBCH |
| KEGG ID | vch:VCA0124 |
| PDB ID | 4NOO, 4NSR, 4NSO |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-3 | MNN |
| Transmembrane helix | 4-23 | LLSAYVTMLLILLSISGGAI |
| Inside | 24-122 | ASENCNDTSGVHQKILVCIQNEIAKSETQIRNNISSKSIDYGFPDDFYSKQRLAIHEKCMLYINVGGQRGELLMNQCELSMLQGLDIYIQQYIEDVDNS |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| SP(Sec/SPI) | 0.9771 | pos: 24-25. AIA-SE. | MNNLLSAYVTMLLILLSISGGAIA |
Protein sequence: 123 a.a. .
>IMU00172 NC_002506:140631-140999 [Vibrio cholerae O1 biovar El Tor str. N16961]
MNNLLSAYVTMLLILLSISGGAIASENCNDTSGVHQKILVCIQNEIAKSETQIRNNISSKSIDYGFPDDFYSKQRLAIHE
KCMLYINVGGQRGELLMNQCELSMLQGLDIYIQQYIEDVDNS*
MNNLLSAYVTMLLILLSISGGAIASENCNDTSGVHQKILVCIQNEIAKSETQIRNNISSKSIDYGFPDDFYSKQRLAIHE
KCMLYINVGGQRGELLMNQCELSMLQGLDIYIQQYIEDVDNS*
Nucleotide sequence: 369 bp .
>IMU00172 NC_002506:140631-140999 [Vibrio cholerae O1 biovar El Tor str. N16961]
ATGAATAACTTGCTTTCTGCGTATGTAACTATGCTGTTGATATTATTAAGTATTAGTGGTGGCGCTATTGCTAGTGAAAA
CTGCAATGATACATCTGGAGTGCATCAAAAAATTCTAGTGTGTATCCAAAATGAGATAGCTAAGTCAGAGACTCAGATTA
GAAATAATATTTCTTCTAAGTCTATAGATTATGGCTTTCCTGATGATTTCTACAGCAAGCAAAGATTAGCTATTCATGAA
AAGTGTATGCTTTATATAAATGTCGGTGGCCAACGTGGTGAATTGCTAATGAACCAATGTGAACTTTCGATGCTACAAGG
CCTTGATATTTACATTCAACAGTATATAGAGGATGTTGATAATAGTTAG
ATGAATAACTTGCTTTCTGCGTATGTAACTATGCTGTTGATATTATTAAGTATTAGTGGTGGCGCTATTGCTAGTGAAAA
CTGCAATGATACATCTGGAGTGCATCAAAAAATTCTAGTGTGTATCCAAAATGAGATAGCTAAGTCAGAGACTCAGATTA
GAAATAATATTTCTTCTAAGTCTATAGATTATGGCTTTCCTGATGATTTCTACAGCAAGCAAAGATTAGCTATTCATGAA
AAGTGTATGCTTTATATAAATGTCGGTGGCCAACGTGGTGAATTGCTAATGAACCAATGTGAACTTTCGATGCTACAAGG
CCTTGATATTTACATTCAACAGTATATAGAGGATGTTGATAATAGTTAG