Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00529  |
| T6SS type | Type i5 |
| Strain | Vibrio furnissii NCTC 11218 |
| Replicon (RefSeq) | chromosome II (NC_016628) |
| Location | 808587..832165 |
| Function | - |
| Comment | - |
| References | - |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | PAAR | TssA | TssB | TssC | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| VFU_RS19110 | 803889..804182 | - | 294 | WP_004727586.1 | hypothetical protein | ||
| VFU_RS19115 | 804418..805266 | + | 849 | WP_014257716.1 | pirin family protein | ||
| VFU_RS19120 | 805426..806112 | - | 687 | WP_014257717.1 | response regulator | ||
| VFU_RS23920 | 806392..807249 | - | 858 | WP_202944803.1 | HAMP domain-containing protein | ||
| VFU_RS23925 | 807188..807793 | - | 606 | WP_014257719.1 | hypothetical protein | ||
| VFU_RS19130 | 807787..808509 | - | 723 | WP_041943437.1 | protein kinase family protein | ||
| T6CP005606 | TssM | VFU_RS19135 (tssM) | 808587..811997 | - | 3411 | WP_014257721.1 | type VI secretion system membrane subunit TssM |
| T6CP005607 | TssL | VFU_RS19140 (icmH) | 812010..813227 | - | 1218 | WP_014257722.1 | type IVB secretion system protein IcmH/DotU |
| T6CP005608 | TssK | VFU_RS19145 (tssK) | 813232..814521 | - | 1290 | WP_014257723.1 | type VI secretion system baseplate subunit TssK |
| T6CP005609 | TssJ | VFU_RS19150 (tssJ) | 814568..815083 | - | 516 | WP_004727578.1 | type VI secretion system lipoprotein TssJ |
| T6CP011964 | FHA | VFU_RS19155 | 815080..816069 | - | 990 | WP_014257724.1 | FHA domain-containing protein |
| VFU_RS19160 | 816078..816812 | - | 735 | WP_014257725.1 | transporter substrate-binding domain-containing protein | ||
| VFU_RS19165 (tssH) | 816809..819427 | - | 2619 | pseudogene | type VI secretion system ATPase TssH | ||
| T6CP005612 | TssG | VFU_RS19170 | 819393..820418 | - | 1026 | WP_004727574.1 | type VI secretion system baseplate subunit TssG |
| T6CP005613 | TssF | VFU_RS19175 (tssF) | 820409..822184 | - | 1776 | WP_014257728.1 | type VI secretion system baseplate subunit TssF |
| T6CP008957 | TssE | VFU_RS19180 (tssE) | 822177..822599 | - | 423 | WP_004727572.1 | type VI secretion system baseplate subunit TssE |
| T6CP005614 | TssC | VFU_RS19185 | 822596..824020 | - | 1425 | WP_014257729.1 | type VI secretion system contractile sheath large subunit |
| T6CP005615 | TssC | VFU_RS19190 (tssC) | 824049..825527 | - | 1479 | WP_014257730.1 | type VI secretion system contractile sheath large subunit |
| T6CP005616 | TssB | VFU_RS19195 (tssB) | 825524..826030 | - | 507 | WP_004727570.1 | type VI secretion system contractile sheath small subunit |
| VFU_RS19200 | 826054..826578 | - | 525 | WP_004727569.1 | type VI secretion system tube protein Hcp | ||
| T6CP005617 | TssA | VFU_RS19205 | 826729..828063 | - | 1335 | WP_014257731.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| VFU_RS19210 | 828096..829175 | - | 1080 | WP_004727567.1 | hypothetical protein | ||
| T6CP011965 | PAAR | VFU_RS19215 | 829228..829518 | - | 291 | WP_014257732.1 | PAAR domain-containing protein |
| VFU_RS19220 | 829518..830099 | - | 582 | WP_014257733.1 | hypothetical protein | ||
| T6CP005618 | TssI | VFU_RS19225 (tssI) | 830102..832165 | - | 2064 | WP_014257734.1 | type VI secretion system tip protein VgrG |
| VFU_RS19230 | 832205..833212 | - | 1008 | WP_014257735.1 | ABC transporter substrate-binding protein | ||
| VFU_RS19235 | 833209..835320 | - | 2112 | WP_014257736.1 | MFS transporter | ||
| VFU_RS19240 | 835317..836123 | - | 807 | WP_014257737.1 | hypothetical protein | ||
| VFU_RS19245 | 836508..836789 | - | 282 | WP_004727560.1 | DUF1255 family protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0001 |
vfu_A02134 (ihfA) | protein | Transcription regulator | Vibrio furnissii NCTC 11218 | chromosome (NC_016602) | 2226951..2227244 (-) | 490864172 | tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓) |
| REG0002 |
vfu_A02422 (ihfB) | protein | Transcription regulator | Vibrio furnissii NCTC 11218 | chromosome (NC_016602) | 2516092..2516376 (-) | 490864456 | tssD2_a promoter (↓); VflT6SS2 major cluster promoter (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|