Detailed information of effector
Summary
| Effector ID | EFF76626  |
| Effector type | Tae |
| Cognate immunity protein | IMU38206 |
| Related T6SS (Type) | T6SS00790 (Type i1) |
| Strain | Vibrio cholerae V52 |
| Replicon | chromosome |
| Sequence | Protein sequence (224 a.a.); Nucleotide sequence (672 bp) |
| Description | - |
| Reference | - |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | VCV52_RS00220 |
| Coordinates (Strand) | 32099..32770 (-) |
| NCBI ID | WP_000132861.1 |
| RefSeq | NZ_KQ410497 |
| Uniprot ID | Q9KMN9_VIBCH, A0A0X1L2B8_VIBCO, A0A0H3AEA5_VIBC3, A0A0K9UY08_VIBCL, A0A7U8ZNG3_VIBCL, A0A0H3Q2N3_VIBCL, C3LUV6_VIBCM, A0A0H7IDZ2_VIBCL |
| KEGG ID | vcm:VCM66_A0284, vcq:EN18_00150, vcx:VAA049_1600, vco:VC0395_0944, vch:VCA0285 |
| PDB ID | 6V98 |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-223 | MTDTVSSTPVADTTPYEIFLSGNDDFLIPVVFPDYLISVADEQSFELWGVKIKTPAVKAPYLGHAGVILINGETGVTRYYEYGRYKNPKSDIPGNVRKVGVSNVTIKSGLITESSLLKVLKEVSLRSGQEGRISGVVLRGKFFSEADSWLRGKMDLNNSPDKIPYDLDSHNCMTFVIDLADAMGLDPAWKPPVVVPSAYIEQFQLSEIDLDYDYKTNKLTVSE |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9894 | - | - |
Protein sequence: 224 a.a. .
>EFF76626 NZ_KQ410497:c32770-32099 Type VI Amidase Effector (Tae) [Vibrio cholerae V52]
MTDTVSSTPVADTTPYEIFLSGNDDFLIPVVFPDYLISVADEQSFELWGVKIKTPAVKAPYLGHAGVILINGETGVTRYY
EYGRYKNPKSDIPGNVRKVGVSNVTIKSGLITESSLLKVLKEVSLRSGQEGRISGVVLRGKFFSEADSWLRGKMDLNNSP
DKIPYDLDSHNCMTFVIDLADAMGLDPAWKPPVVVPSAYIEQFQLSEIDLDYDYKTNKLTVSE*
MTDTVSSTPVADTTPYEIFLSGNDDFLIPVVFPDYLISVADEQSFELWGVKIKTPAVKAPYLGHAGVILINGETGVTRYY
EYGRYKNPKSDIPGNVRKVGVSNVTIKSGLITESSLLKVLKEVSLRSGQEGRISGVVLRGKFFSEADSWLRGKMDLNNSP
DKIPYDLDSHNCMTFVIDLADAMGLDPAWKPPVVVPSAYIEQFQLSEIDLDYDYKTNKLTVSE*
Nucleotide sequence: 672 bp .
>EFF76626 NZ_KQ410497:c32770-32099 Type VI Amidase Effector (Tae) [Vibrio cholerae V52]
ATGACTGACACTGTATCATCAACTCCAGTAGCCGATACAACTCCATATGAGATATTTCTTTCAGGTAATGACGATTTTTT
GATACCTGTAGTATTTCCTGACTACCTAATCTCAGTCGCAGATGAACAATCTTTTGAGTTATGGGGTGTAAAAATAAAAA
CTCCTGCAGTGAAGGCCCCCTACCTTGGTCACGCTGGAGTTATTTTGATTAATGGTGAAACAGGTGTTACTCGCTATTAT
GAGTATGGCCGTTACAAGAACCCTAAATCGGATATCCCAGGAAATGTGAGGAAGGTTGGGGTATCAAATGTAACTATAAA
AAGTGGTCTAATTACTGAAAGCTCGTTACTGAAGGTTCTTAAAGAAGTGTCCCTACGTTCTGGACAGGAGGGGAGAATTT
CGGGAGTGGTATTAAGAGGAAAGTTTTTCTCTGAAGCAGATTCATGGTTAAGGGGAAAAATGGATCTTAATAATAGCCCT
GATAAGATACCTTATGACTTGGATAGCCATAACTGCATGACATTTGTCATAGATTTAGCTGATGCAATGGGGTTAGACCC
GGCTTGGAAACCTCCTGTTGTTGTACCAAGCGCGTATATTGAACAGTTTCAGTTAAGTGAAATTGATTTAGATTATGACT
ATAAGACCAACAAATTAACGGTATCTGAGTGA
ATGACTGACACTGTATCATCAACTCCAGTAGCCGATACAACTCCATATGAGATATTTCTTTCAGGTAATGACGATTTTTT
GATACCTGTAGTATTTCCTGACTACCTAATCTCAGTCGCAGATGAACAATCTTTTGAGTTATGGGGTGTAAAAATAAAAA
CTCCTGCAGTGAAGGCCCCCTACCTTGGTCACGCTGGAGTTATTTTGATTAATGGTGAAACAGGTGTTACTCGCTATTAT
GAGTATGGCCGTTACAAGAACCCTAAATCGGATATCCCAGGAAATGTGAGGAAGGTTGGGGTATCAAATGTAACTATAAA
AAGTGGTCTAATTACTGAAAGCTCGTTACTGAAGGTTCTTAAAGAAGTGTCCCTACGTTCTGGACAGGAGGGGAGAATTT
CGGGAGTGGTATTAAGAGGAAAGTTTTTCTCTGAAGCAGATTCATGGTTAAGGGGAAAAATGGATCTTAATAATAGCCCT
GATAAGATACCTTATGACTTGGATAGCCATAACTGCATGACATTTGTCATAGATTTAGCTGATGCAATGGGGTTAGACCC
GGCTTGGAAACCTCCTGTTGTTGTACCAAGCGCGTATATTGAACAGTTTCAGTTAAGTGAAATTGATTTAGATTATGACT
ATAAGACCAACAAATTAACGGTATCTGAGTGA