Detailed information of immunity protein
Summary
| Immunity protein ID | IMU00156  |
| Cognate effector | EFF00008 |
| Related T6SS (Type) | T6SS00002 (Type i1) |
| Strain | Vibrio cholerae O1 biovar El Tor str. N16961 |
| Replicon | chromosome |
| Sequence | Protein sequence (248 a.a.); Nucleotide sequence (744 bp) |
| Description | TsiV1 |
| Reference | - |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | VC1419 (TsiV1) |
| Coordinates (Strand) | 1516533..1517276 (+) |
| NCBI ID | 15641430 |
| RefSeq | NC_002505 |
| Uniprot ID | TSIV1_VIBCH |
| KEGG ID | vch:VC1419 |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Inside | 1-11 | MKLLNNLAIKK |
| Transmembrane helix | 12-30 | LISVVVLFIALFFLGYDYY |
| Outside | 31-247 | QTSQPNIWGDEPDESYITISGKKPIDAYLEVWTHFWVTGDECEAYSYDLFGQKAHQGGKISQKITHDFAKDGSNFEFRIPYQTYKNSQNCIVELRDFSIQAHNDFDTVGFAQLRFSPAGREYYNREVDLNSLITADNCNSDIFKSIRKEWAGAIGCHFYVDGKKKTKDEEFNAYTIYYDFSKFNNDTVIHYDILAGENYRSEPLSSAQKTAVVSDDN |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9251 | - | - |
Protein sequence: 248 a.a. .
>IMU00156 NC_002505:1516533-1517276 [Vibrio cholerae O1 biovar El Tor str. N16961]
MKLLNNLAIKKLISVVVLFIALFFLGYDYYQTSQPNIWGDEPDESYITISGKKPIDAYLEVWTHFWVTGDECEAYSYDLF
GQKAHQGGKISQKITHDFAKDGSNFEFRIPYQTYKNSQNCIVELRDFSIQAHNDFDTVGFAQLRFSPAGREYYNREVDLN
SLITADNCNSDIFKSIRKEWAGAIGCHFYVDGKKKTKDEEFNAYTIYYDFSKFNNDTVIHYDILAGENYRSEPLSSAQKT
AVVSDDN*
MKLLNNLAIKKLISVVVLFIALFFLGYDYYQTSQPNIWGDEPDESYITISGKKPIDAYLEVWTHFWVTGDECEAYSYDLF
GQKAHQGGKISQKITHDFAKDGSNFEFRIPYQTYKNSQNCIVELRDFSIQAHNDFDTVGFAQLRFSPAGREYYNREVDLN
SLITADNCNSDIFKSIRKEWAGAIGCHFYVDGKKKTKDEEFNAYTIYYDFSKFNNDTVIHYDILAGENYRSEPLSSAQKT
AVVSDDN*
Nucleotide sequence: 744 bp .
>IMU00156 NC_002505:1516533-1517276 [Vibrio cholerae O1 biovar El Tor str. N16961]
ATGAAGTTATTGAATAATCTTGCAATAAAAAAGCTAATCTCAGTTGTTGTACTATTCATTGCATTATTTTTTCTTGGGTA
TGACTATTACCAGACTTCTCAACCTAATATTTGGGGTGATGAACCTGATGAGTCCTATATTACTATATCAGGCAAAAAGC
CTATAGATGCTTATTTAGAAGTGTGGACTCATTTTTGGGTGACAGGAGATGAGTGTGAAGCTTATTCCTACGATTTATTT
GGTCAAAAAGCCCATCAAGGAGGAAAAATAAGCCAGAAGATTACGCATGATTTTGCTAAAGATGGTTCAAATTTTGAATT
TAGAATTCCTTACCAAACGTATAAGAACTCACAAAATTGTATAGTGGAATTAAGAGACTTTTCCATACAAGCTCATAATG
ATTTTGATACCGTAGGTTTTGCTCAGTTGCGATTTTCTCCAGCAGGCAGAGAATATTACAATCGAGAGGTTGATCTAAAC
TCATTGATTACAGCAGATAATTGCAATAGTGATATATTTAAAAGTATAAGAAAAGAGTGGGCAGGAGCCATTGGTTGTCA
TTTTTATGTCGATGGAAAGAAAAAGACTAAAGATGAAGAATTCAACGCTTACACCATCTACTACGATTTTTCGAAATTCA
ATAATGACACCGTGATTCATTACGATATTTTAGCCGGTGAAAACTATCGGTCAGAGCCTTTGTCCTCAGCTCAAAAGACA
GCAGTGGTATCTGATGATAATTAA
ATGAAGTTATTGAATAATCTTGCAATAAAAAAGCTAATCTCAGTTGTTGTACTATTCATTGCATTATTTTTTCTTGGGTA
TGACTATTACCAGACTTCTCAACCTAATATTTGGGGTGATGAACCTGATGAGTCCTATATTACTATATCAGGCAAAAAGC
CTATAGATGCTTATTTAGAAGTGTGGACTCATTTTTGGGTGACAGGAGATGAGTGTGAAGCTTATTCCTACGATTTATTT
GGTCAAAAAGCCCATCAAGGAGGAAAAATAAGCCAGAAGATTACGCATGATTTTGCTAAAGATGGTTCAAATTTTGAATT
TAGAATTCCTTACCAAACGTATAAGAACTCACAAAATTGTATAGTGGAATTAAGAGACTTTTCCATACAAGCTCATAATG
ATTTTGATACCGTAGGTTTTGCTCAGTTGCGATTTTCTCCAGCAGGCAGAGAATATTACAATCGAGAGGTTGATCTAAAC
TCATTGATTACAGCAGATAATTGCAATAGTGATATATTTAAAAGTATAAGAAAAGAGTGGGCAGGAGCCATTGGTTGTCA
TTTTTATGTCGATGGAAAGAAAAAGACTAAAGATGAAGAATTCAACGCTTACACCATCTACTACGATTTTTCGAAATTCA
ATAATGACACCGTGATTCATTACGATATTTTAGCCGGTGAAAACTATCGGTCAGAGCCTTTGTCCTCAGCTCAAAAGACA
GCAGTGGTATCTGATGATAATTAA