Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01029  |
| T6SS type | Type i5 |
| Strain | Vibrio fluvialis 85003 |
| Replicon (GenBank) | chromosome (KY319184) |
| Location | 1341..24915 |
| Function | anti-bacterial |
| Comment | V.fluvialis 85003 can secrete hcp and shows VflT6SS2-dependent competition with E.coli strain MG1655. |
| References | [1] Huang Y, Du P, Zhao M, Liu W, Du Y, Diao B, Li J, Kan B, Liang W. et al (2017) Functional Characterization and Conditional Regulation of the Type VI Secretion System in Vibrio fluvialis.. Front Microbiol. 0.7. [PudMed:28424671] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssF | TssG | TssH | TssI | TssJ | TssK | TssM |
| Number | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| Locus_01 | 1..547 | - | 547 | 1185549765 | periplasmic sensor signal transduction histidine kinase | ||
| Locus_02 | 547..1287 | - | 741 | 1185549766 | cyclic nucleotide-binding protein kinase | ||
| T6CP013343 | TssM | Locus_03 (tssM1) | 1341..4751 | - | 3411 | 1185549767 | type VI secretion system protein ImpL |
| Locus_04 (tssL1) | 4764..5984 | - | 1221 | 1185549768 | type VI secretion system protein ImpK | ||
| T6CP013344 | TssK | Locus_05 (tssK1) | 5989..7278 | - | 1290 | 1185549769 | type VI secretion system protein ImpJ |
| T6CP013345 | TssJ | Locus_06 (tssJ1) | 7325..7840 | - | 516 | 1185549770 | type VI secretion system protein VasD |
| Locus_07 (tagH1) | 7837..8826 | - | 990 | 1185549771 | type VI secretion system protein ImpI/VasC | ||
| Locus_08 | 8835..9569 | - | 735 | 1185549772 | hypothetical protein | ||
| T6CP013346 | TssH | Locus_09 (tssH1) | 9566..12184 | - | 2619 | 1185549773 | ClpB protein |
| T6CP013347 | TssG | Locus_10 (tssG1) | 12150..13175 | - | 1026 | 1185549774 | type VI secretion system protein ImpH |
| T6CP013348 | TssF | Locus_11 (tssF1) | 13166..14941 | - | 1776 | 1185549775 | type VI secretion system protein ImpG/VasA |
| Locus_12 (tssE1) | 14934..15356 | - | 423 | 1185549776 | ImpF-like protein | ||
| T6CP013349 | TssC | Locus_13 (impD) | 15353..16777 | - | 1425 | 1185549777 | type VI secretion system protein ImpD |
| T6CP013350 | TssC | Locus_14 (tssC1) | 16806..18284 | - | 1479 | 1185549778 | type VI secretion system protein ImpC |
| T6CP013351 | TssB | Locus_15 (tssB1) | 18284..18787 | - | 504 | 1185549779 | type VI secretion system protein ImpB |
| T6CP013352 | TssD | Locus_16 (tssD1) | 18811..19335 | - | 525 | 1185549780 | type VI secretion system secreted protein Hcp |
| T6CP013353 | TssA | Locus_17 (tssA1) | 19486..20811 | - | 1326 | 1185549781 | type VI secretion system protein ImpA |
| Locus_18 | 20844..21923 | - | 1080 | 1185549782 | hypothetical protein | ||
| Locus_19 (paar) | 21984..22268 | - | 285 | 1185549783 | PAAR repeat-containing protein | ||
| Locus_20 | 22268..22849 | - | 582 | 1185549784 | hypothetical protein | ||
| T6CP013354 | TssI | Locus_21 (rhs) | 22852..24915 | - | 2064 | 1185549785 | Rhs element Vgr family protein |
| Locus_22 | 24955..25962 | - | 1008 | 1185549786 | ABC-type uncharacterized transport system periplasmic component | ||
| Locus_23 | 25959..28070 | - | 2112 | 1185549787 | MFS transporter | ||
| Locus_24 | 28067..28873 | - | 807 | 1185549788 | hypothetical protein | ||
| Locus_25 | 29409..29690 | - | 282 | 1185549789 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0373 |
hapR | protein | QS regulatory pathway | Vibrio fluvialis 85003 | chromosome (KY319184) | - | - | vgrG (↓) |
| REG0374 |
ihfA | protein | QS regulatory pathway | Vibrio fluvialis 85003 | chromosome (KY319184) | - | - | vgrG (↓) |
| REG0375 |
ihfB | protein | QS regulatory pathway | Vibrio fluvialis 85003 | chromosome (KY319184) | - | - | vgrG (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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